COVID - Spplement VACCINE ADJ DISCOVERY PROGRAM (VADP)
COVID - Spplement VACCINE ADJ DISCOVERY PROGRAM (VADP)
批准号:
10301500
负责人:
JAY EVANS
金额:
$369.97万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-09-30 至 2020-09-29
关键词:
2019-nCoVAdjuvantAntibodiesAntibody titer measurementAntigensBaculovirus Expression SystemCellsCellular ImmunityContractsDevelopmentDiseaseEquipmentEvaluationFerretsFormulationHumanHuman ResourcesHumoral ImmunitiesInfectionLeadLengthModelingMucous MembraneMusParticle SizeProductionProteinsRecombinant ProteinsRecombinantsResourcesSARS coronavirusSerumSideT cell responseTestingTransgenic MiceVaccine AdjuvantVaccine ProductionVaccinescoronavirus diseasecytokineeffector T cellimmunogenicityin vivoin vivo evaluationprogramsreceptorreceptor bindingvaccine candidatevaccine efficacyvaccine evaluationvaccine safety
中文摘要
为了确定重组SARS-CoV2疫苗的最佳佐剂,并确定预防SARS-CoV2感染或疾病的相关因素,将用一组不同的疫苗佐剂配制实验性SARS-CoV2疫苗,并并排测试免疫原性和有效性。
英文摘要
To identify the optimal adjuvant for recombinant SARS-CoV2 vaccines, and to identify correlates of protection against SARS-CoV2 infection or disease, experimental SARS-CoV2 vaccines will be formulated with a panel of different vaccine adjuvants and tested side-by-side for immunogenicity and efficacy.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
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依托单位:
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依托单位:
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依托单位:
海外基金