Cancer Grand Challenges: Operations Management Application

癌症大挑战：运营管理应用

• 批准号: 10283383
• 负责人: David Scott
• 金额: $ 91.36万
• 依托单位: CANCER RESEARCH UNITED KINGDOM
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-10 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10283383
• 关键词: Cancer; Grand; Challenges; Operations; Management

Cancer Research UK (CRUK) established its ‘Grand Challenge’ initiative in 2015 to support international, interdisciplinary teams of elite scientists and clinicians to address some of the biggest problems in cancer research. Following positive and productive discussions between CRUK and NCI in 2019, it was agreed that a partnership would be formed to evolve CRUK Grand Challenge into Cancer Grand Challenges (CGC). The two organisations signed a Memorandum of Understanding (MoU) in February 2020 committing to partner in funding four new teams biennially over three cycles. The partners agreed a number of guiding principles, namely that CGC will: Tackle important challenges in cancer that require a multi-disciplinary approach to solve, and span discovery, clinical and population sciences; Be developed and shaped in consultation with the global cancer research community; Be international, and enable the best scientists to collaborate irrespective of geographical boundaries; Provide funding at scale in order to enable imaginative thinking; Embrace partnerships with other funding agencies, commercial organisations and private philanthropists. The MoU also provided that CRUK would lead on the delivery of the operations for CGC, moreover that NCI would support through an other transactions agreement 50% of the properly vouchered costs per year (including the cost of time incurred by CRUK employees) incurred by CRUK in its role as operational manager, subject to available funds. This other transactions application/award details CRUK’s responsibilities, specifically coordinating: The challenge-setting process; The two-stage application process for each round of CGC; Meetings of the CGC Joint Steering Committee and Scientific Committee; The release of funding by CRUK and NCI to each participating institution; Annual and end-of-grant scientific and financial reporting from funded teams; The delivery of an annual Scientific Summit and trainee meeting; CGC advocacy activity; Efforts to market the initiative and communicate its impact. In delivering all of the above, CRUK will work in close collaboration and consultation with NCI.

英国癌症研究中心(CRUK)于2015年设立了“大挑战”计划，以支持由精英科学家和临床医生组成的国际跨学科团队，以解决癌症研究中的一些最大问题。 在CRUK和NCI在2019年进行了积极和富有成效的讨论后，双方同意建立合作伙伴关系，将CRUK大挑战演变为癌症大挑战(CGC)。这两个组织在2020年2月签署了一份谅解备忘录(MoU)，承诺在三个周期内每两年资助四个新团队。 合作伙伴商定了一些指导原则，即CGC将： 应对癌症方面的重大挑战，这些挑战需要多学科方法来解决，并跨越发现、临床和人口科学； 与全球癌症研究界协商制定和形成； 国际化，使最优秀的科学家能够不分地域进行合作； 大规模提供资金，以促进想象力思维； 接受与其他资助机构、商业组织和私人慈善家的伙伴关系。 谅解备忘录亦规定，华润置地将牵头为华润置业有限公司提供营运服务，此外，在可用资金的规限下，华润置业将透过其他交易协议，支持华润置业有限公司在担任营运经理期间每年所招致的适当凭单成本的50%(包括华润置地雇员所招致的时间成本)。 该其他交易申请/裁决详细说明了CRUK的职责，特别是协调： 挑战设定过程； 每一轮CGC的两阶段申请程序； CGC联合指导委员会和科学委员会的会议； CRUK和NCI向每个参与机构发放资金； 受资助团队的年度和赠款终了科学和财务报告； 举办年度科学首脑会议和实习生会议； CGC宣传活动； 努力推销这一倡议并传达其影响。 在实现上述所有目标的过程中，CRUK将与NCI密切合作和协商。