Cancer Grand Challenges: Operations Management Application

癌症大挑战：运营管理应用

• 批准号: 10893060
• 负责人: David Scott
• 金额: $ 111.38万
• 依托单位: CANCER RESEARCH UNITED KINGDOM
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-10 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10893060
• 关键词: Cancer; Grand; Challenges; Operations; Management

Cancer Research UK (CRUK) established its ‘Grand Challenge’ initiative in 2015 to support international, interdisciplinary teams of elite scientists and clinicians to address some of the biggest problems in cancer research. Following positive and productive discussions between CRUK and NCI in 2019, it was agreed that a partnership would be formed to evolve CRUK Grand Challenge into Cancer Grand Challenges (CGC). The two organisations signed a Memorandum of Understanding (MoU) in February 2020 committing to partner in funding four new teams biennially over three cycles. The partners agreed a number of guiding principles, namely that CGC will: Tackle important challenges in cancer that require a multi-disciplinary approach to solve, and span discovery, clinical and population sciences; Be developed and shaped in consultation with the global cancer research community; Be international, and enable the best scientists to collaborate irrespective of geographical boundaries; Provide funding at scale in order to enable imaginative thinking; Embrace partnerships with other funding agencies, commercial organisations and private philanthropists. The MoU also provided that CRUK would lead on the delivery of the operations for CGC, moreover that NCI would support through an other transactions agreement 50% of the properly vouchered costs per year (including the cost of time incurred by CRUK employees) incurred by CRUK in its role as operational manager, subject to available funds. This other transactions application/award details CRUK’s responsibilities, specifically coordinating: The challenge-setting process; The two-stage application process for each round of CGC; Meetings of the CGC Joint Steering Committee and Scientific Committee; The release of funding by CRUK and NCI to each participating institution; Annual and end-of-grant scientific and financial reporting from funded teams; The delivery of an annual Scientific Summit and trainee meeting; CGC advocacy activity; Efforts to market the initiative and communicate its impact. In delivering all of the above, CRUK will work in close collaboration and consultation with NCI.

英国癌症研究中心（CRUK）于2015年建立了“大挑战”计划，以支持由精英科学家和临床医生组成的国际跨学科团队解决癌症研究中的一些最大问题。 在2019年CRUK和NCI进行了积极和富有成效的讨论后，双方同意建立合作伙伴关系，将CRUK Grand Challenge发展为Cancer Grand Challenge（CGC）。这两个组织于2020年2月签署了一份谅解备忘录（MoU），承诺在三个周期内每两年资助四个新团队。 合作伙伴商定了一些指导原则，即CGC将： 应对癌症的重要挑战，需要多学科的方法来解决，并跨越发现，临床和人口科学; 与全球癌症研究界协商制定和塑造; 具有国际性，使最优秀的科学家能够不受地理边界的限制进行合作; 提供大规模资金，以便能够进行富有想象力的思考; 与其他资助机构、商业组织和私人慈善家建立伙伴关系。 谅解备忘录还规定，CRUK将牵头为CGC交付运营，此外，NCI将通过其他交易协议支持CRUK作为运营经理每年产生的50%的适当担保成本（包括CRUK员工产生的时间成本），但须视可用资金而定。 该其他交易申请/授予详细说明了CRUK的责任，特别是协调： 挑战设定过程; 每轮CGC的两阶段申请流程; 理事会联合指导委员会和科学委员会会议; CRUK和NCI向每个参与机构发放资金; 受资助团队的年度和赠款结束时的科学和财务报告; 举办年度科学峰会和学员会议; CGC宣传活动; 努力推销倡议并宣传其影响。 在实现上述所有目标时，CRUK将与NCI密切合作和协商。