Individual Differences in Dementia Spousal Caregiver Burden: A Biobehavioral Approach

摘要 家长项目的目标是了解哪些AD配偶照顾者最容易受到 配偶痴呆症患者在生活体验中的照顾对身体健康的有害影响 丧失亲人，同时应对照顾和努力维持生活质量的负担。作为一个探索性目标， 我们将考察这些依恋取向的个体如何影响婚姻关系的两个成员 王朝式的。320名AD配偶照顾者将完成依恋、生活质量、 照顾者负担、悲伤症状，并参与抽血以评估炎症和GCR，以及HF- 心率变异性在两年内变化四次。他们还将参加一个关于AD的简短采访 配偶的生活质量和依恋取向。轻至中度AD的AD患者也将回答问题 以前在AD患者中使用，用于评估依恋和生活质量。 这项研究旨在描述阿尔茨海默病配偶照顾者之间的联系 附属公司污名的经历，指的是公众对自己的负面观点的国际化， 焦虑、抑郁和副交感神经活动，以心率变异性为指标。以前的研究 这表明照顾者容易遭受耻辱，这会导致慢性压力，因此， 自主神经失衡，这是心血管疾病的预兆。然而，据我们所知，目前还没有研究表明 思考从属公司污名的不利影响如何影响AD配偶的副交感活动 照顾者。我们预计，经历较高附属公司污名的AD配偶照顾者将与 焦虑和抑郁程度增加，心率变异性水平降低。我们必须设法理解这些 更好的互动，所以我们可以确定哪些AD配偶照顾者最容易受到不利健康的影响 这将有助于减少关联污名的影响，并提供有针对性的治疗，以减轻AD照护的巨大压力。

ABSTRACT The goal of the parent project is to understand which AD spousal caregivers are most vulnerable to the deleterious physical health effects of spousal dementia caregiving as they navigate the experience of living bereavement, while coping with the burden of caregiving and trying to maintain QOL. As an exploratory aim, we will examine how these individual in attachment orientation affect both members of the marital relationship dyadically. Three hundred and twenty AD spousal caregivers will complete assessments of attachment, QOL, caregiver burden, grief symptoms, and participate in a blood draw to evaluate inflammation and GCR, and HF- HRV four times over a two-year period. They will also participate in a brief interview in reference to the AD spouse's QOL and attachment orientation. The AD patient with mild to moderate AD will also answer questions used previously among AD patients to assess attachment and QOL. The present study aims to characterize the association between Alzheimer's Disease spousal caregivers' experience of affiliate stigma, which refers to the internationalization of negative public views toward oneself, anxiety and depression and parasympathetic activity, as indexed by heart rate variability. Previous research suggests that caregivers are subject to experiencing stigma that contributes to chronic stress, and consequently, autonomic imbalance, which is predictive of cardiovascular disease. Yet, to our knowledge, no study exists that considers how the adverse effects of affiliate stigma influence parasympathetic activity among AD spousal caregivers. We anticipate that AD spousal caregivers who experience higher affiliate stigma will associate with increased levels of anxiety and depression and decreased levels of HRV. We must seek to understand these interactions better, so we may determine which AD spousal caregivers are most disposed to the adverse health effects of affiliate stigma and provide targeted treatments to alleviate the intense stress of AD caregiving.