Cognitive Load Measurement during Neuromyoelectric Prosthesis Use with Sensory Feedback and Intuitive Motor Control

项目摘要 拟议工作的主要目标是确定是否感觉反馈和扩展使用 减少用于控制先进的灵巧和传感器化假肢的认知负荷。假体 用于上肢截肢者的技术正在迅速发展。物理改善涉及两个方面 组件：机器人肢体和神经肌肉接口。尽管创新有望增加 假肢功能，上肢假肢的放弃率很高（高达50%）。科学 社区正在开发先进的控制范例，提供更直观的控制和使用触觉传感器 来恢复触觉这些进步有可能提高满意率， 放弃率;然而，目前的指标不考虑用户的努力，这是必要的，在确定一个 可行的产品假肢系统的改进，无论是通过更直观的控制模式还是通过感官 反馈通常通过任务中的表现来量化， 活动虽然这些指标是有用的，但它们不一定反映最终用户的偏好。 尽管特定系统可以实现精细控制，但是实现这种控制所需的努力可能是不必要的。 禁止常规使用，导致产品无活力。因此，在此结合努力的措施， 被描述为认知负荷，可以更完整地告知假体系统的期望特性。 本提案的主要目的是测量假体使用期间的认知负荷。我们建议 调整在其他领域中使用的认知负荷测量（例如，推动研究），以先进的 神经肌电假肢我们的第一个目标是开发一个强大的方法来测量认知负荷， 生理、行为和受试者测量，包括瞳孔测量、心电图和 脑电图（Aim 1）。目标1将揭示特定认知负荷的优点和局限性 在假肢研究方面的措施。然后，我们将应用这些方法来确定感觉反馈是否可以减少 使用假肢期间的认知负荷（目标2）。目的2阐明感觉反馈在假肢中的作用 使用，在现场的电流推力。最后，我们将确定认知负荷是否在延长（六个月）期间下降。 在家中使用先进的神经肌电假肢（目标3）。Aim 3将首次探索 在家庭环境中长时间使用高级假肢的认知影响。 这些目标的成功将建立一个根本不同但必不可少的途径， 以患者为中心的方式推进假体的可行性。记录的感觉反馈的有效性 在假肢控制中的长期使用不仅具有科学意义，而且也是将这些 先进的修复技术，以临床接受和使用。总的来说，该项目将提供 这些方法可用于上肢假肢界及其他领域。

Project Summary The primary goal of the proposed work is to determine whether sensory feedback and extended use reduce the cognitive load for controlling an advanced dexterous and sensorized prosthetic limb. Prosthetic technologies for upper-limb amputees are advancing rapidly. The physical improvements involve two components: the robotic limb and the neuromuscular interface. Despite innovations promising increased prosthetic function, high abandonment rates (up to 50%) are seen with upper-limb prostheses. The scientific community is developing advanced control paradigms providing more intuitive control and using haptic sensors to restore the sense of touch. These advancements have the potential to improve satisfaction rates and reduce abandonment rates; however, current metrics do not consider user effort, which is necessary in determining a viable product. Improvements to prosthetic systems, whether through more intuitive control paradigms or sensory feedback are typically quantified through performance in tasks that may or may not represent typical daily activities. Although these metrics are useful, they do not necessarily reflect the preferences of the end-user. Although a particular system may enable fine control, the effort required to achieve such control may be prohibitive to routine use, resulting in a nonviable product. Thus, incorporating measures of effort, herein described as cognitive load, can more completely inform the desirable characteristics of a prosthetic system. The main objective of this proposal is to measure cognitive load during prosthesis use. We propose to adapt cognitive load measures used in other fields (e.g., driving research) to our research with advanced neuromyoelectric prostheses. Our first aim is to develop a robust method for measuring cognitive load through physiological, behavioral, and subject measures, including pupillometry, electrocardiography, and electroencephalography (Aim 1). Aim 1 will expose the advantages and limitations of specific cognitive load measures in prosthetic research. We will then apply these methods to determine if sensory feedback can reduce cognitive load during prosthetic use (Aim 2). Aim 2 elucidates the usefulness of sensory feedback in prosthesis use, a current thrust in the field. Lastly, we will determine if cognitive load decreases during extended (six months) at-home use of an advanced neuromyoelectric prosthesis (Aim 3). Aim 3 will provide the first exploration of the cognitive effects of using an advanced prosthesis in a home setting for an extended period. Success in these aims will establish a fundamentally different yet essential pathway for assessing the viability of prosthesis advancements in a patient-centric manner. Documented effectiveness of sensory feedback and long-term use in prosthetic control is not only of scientific interest, but are also requisite for translating these advanced prosthetic technologies to clinical acceptance and use. Altogether, this project will provide methodologies that can be used in the upper-limb prosthesis community and beyond.