The Aga Khan University Pakistan Initiative for Non-Communicable Diseases (AKUPI-NCDs) Research Training Program

阿迦汗大学巴基斯坦非传染性疾病倡议 (AKUPI-NCD) 研究培训计划

• 批准号: 10301373
• 负责人: Aysha Almas
• 金额: $ 24.82万
• 依托单位: AGA KHAN UNIVERSITY (PAKISTAN)
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-08 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10301373
• 关键词: Big Data; Cerebrovascular Disorders; Cessation of life; Data; Development; Disease Management; Disease Surveillance; Elements; Epidemic; Funding; Health; Information Technology; Infrastructure; Institutes; Lead; Leadership; Longevity; Pakistan; Pathway interactions; Prevalence; Research; Research Personnel; Research Training; Resources; Risk Factors; Site; Testing; Training; Training Programs; United States; Universities; Vision; Work; cerebrovascular; cost; design; digital; disorder prevention; faculty research; global health; implementation science; insight; low and middle-income countries; multidisciplinary; neurovascular; next generation; premature; programs; response; risk sharing; social determinants

PROJECT SUMMARY Non-communicable diseases (NCDs) represent an extraordinary global crisis. Over three quarters of all NCD related deaths and 82% of premature NCD-related deaths occur in low-middle income countries (LMIC). Locally-relevant, high-quality data regarding NCDs are scarce and most low-middle income countries (LMICs) like Pakistan, are not equipped to manage this epidemic. A critical gap in the response of LMICs to the NCD epidemic is a dearth of trained researchers who can contribute to the understanding of prevalence, risk factors, and development and testing of safe, effective, and low-cost solutions. Our prior work funded through the D71 PAR-17-097 mechanism in 2018, shows that there exists a pressing local and national need and desire for high-quality, multidisciplinary, trained professionals to lead teams that are thematically focused on NCD research in Pakistan. We were able to identify high-priority NCD research themes and most suitable research training resources and pathways. Informed by these unique insights we have designed a comprehensive, integrated, multi-disciplinary training program to train the next generation of leaders in NCD research with a particular focus on cardio-cerebrovascular diseases and their shared risk factors. The training program leverages the Aga Khan University’s (AKU) and the Institute for Global Health and Development extensive development network platform and infrastructure at its flagship site in Pakistan. The specific aims of this program are to: 1) Build sustainable research capacity in: (a) high-quality surveillance of risk factors (including social determinants) across the life span common to several NCDs, (b) implementation of context sensitive, scalable, approaches to cardio-cerebro vascular diseases prevention & management in Pakistan. A heavy focus will be research approaches that leverage digital information technology including big data and m-health. 2) Develop a sustainable pool of Pakistani research experts in cardio-neurovascular disease surveillance and implementation science who will provide the vision and leadership necessary to produce high-quality research of relevance to tackling NCDs in Pakistan and other LMICs. The proposed program brings together faculty, research expertise, and resources from the Aga Khan University, Karachi, Pakistan and Duke University, United States. We expect that this program will directly increase Pakistan’s research capacity, a critical element in a comprehensive national NCD response. 1

项目总结 非传染性疾病(NCDs)是一场非同寻常的全球危机。超过四分之三的非传染性疾病 与非传染性疾病相关的死亡和82%的非传染性疾病相关过早死亡发生在中低收入国家。 关于非传染性疾病的与当地相关的高质量数据很少，大多数中低收入国家(LMIC) 像巴基斯坦一样，没有能力控制这种流行病。低收入国家应对非传染性疾病的关键差距 流行病是缺乏训练有素的研究人员，他们能够帮助理解流行率、风险因素、 以及开发和测试安全、有效和低成本的解决方案。我们之前的工作是通过D71资助的 2018年的PAR-17-097机制，表明地方和国家存在迫切的需求和愿望 高素质、多学科、训练有素的专业人员领导以非传染性疾病为主题的团队 在巴基斯坦的研究。我们能够确定高度优先的非传染性疾病研究主题和最合适的研究 培训资源和途径。受这些独特见解的启发，我们设计了一个全面的、 综合的多学科培训计划，培训下一代非传染性疾病研究领域的领导者 特别关注心脑血管疾病及其共同的风险因素。培训计划 利用阿加汗大学(AKU)和全球卫生与发展研究所的广泛 其在巴基斯坦的旗舰站点的开发网络平台和基础设施。这样做的具体目的是 方案的目的是：1)在以下方面建立可持续的研究能力：(A)高质量地监测风险因素(包括 社会决定因素)跨越几个非传染性疾病共有的寿命，(B)实现上下文敏感， 巴基斯坦心脑血管疾病预防和管理的可扩展方法。一个沉重的 重点将是利用包括大数据和移动健康在内的数字信息技术的研究方法。 2)建立一个可持续的巴基斯坦心脑血管疾病监测研究专家队伍 实施科学，将提供产生高质量研究所需的远见和领导 这对解决巴基斯坦和其他小岛屿发展中国家的非传染性疾病具有重要意义。拟议的项目将教职员工聚集在一起， 来自巴基斯坦卡拉奇的阿加汗大学和杜克大学的研究专业知识和资源， 美国。我们预计这一计划将直接提高巴基斯坦的研究能力，一个关键的 这是国家非传染性疾病综合应对措施的重要组成部分。 1