Identification of best practices for biodiversity recovery and public health interventions to prevent future epidemics and pandemics - BEPREP

流行病和大流行--其中大部分是由人畜共患病和病媒传播的新出现的疾病引起的--正在全球范围内以惊人的速度威胁着我们的健康和福利。预防未来的疾病暴发将是确保人类福祉的关键，并要求进行变革性的变革。“生物多样性有益于我们的健康”已成为减少疾病风险的新范式。因此，以恢复生物多样性为目标的自然恢复--单独或与公共卫生干预相结合--已被确定为一种主要的减少疾病风险的工具。虽然全球有数千个正在进行和计划中的自然恢复项目，但我们缺乏以下方面的知识：a)这种恢复是否真的中断了感染-排泄-泄漏-传播的级联，并降低了疾病风险；b)它们是否放大了风险；c)恢复是否具有降低疾病风险的成功因素。BEPREP将填补这方面的知识不足，并提供实际指导。在空间和时间上重复的实地研究和欧洲和热带案例研究的实验中，我们将研究a)-c)，并揭示感染动力学和沿感染-棚子-泄漏-传播级联的驱动因素的原因机制。BEPREP的参与性和跨部门办法，通过积极让土著和当地社区参与，将有助于确定最佳做法恢复和干预的成功因素，包括。以自然为基础的解决方案，以指导未来促进健康生态系统的生物多样性恢复措施。这些成功因素将有助于a)中断感染-散播-泄漏-传播的级联，以及b)最终防止疾病暴发。BEPREP的结果有助于建立一个有准备并对疾病风险做出反应的欧洲社会。因此，作为欧盟绿色协议的核心部分，BEPREP将加快实现欧盟2030年生物多样性战略所需的生态转型，并支持新冠肺炎大流行后的绿色复苏。

Epidemics and pandemics- most of them caused by zoonotic and vector-borne emerging diseases- are globally threatening our health and welfare at an alarming pace. Prevention of future disease outbreaks will be pivotal to secure human welfare and demands transformative change. "Biodiversity-is-good-for-our-health" has become a new paradigm in disease risk mitigation. Consequently, nature restoration targeting biodiversity recovery - isolated or in combination with public health interventions - has been identified as a major disease risk mitigation tool. While there are thousands of ongoing and planned nature restoration projects globally, we lack knowledge a) if such restorations indeed interrupt the infect-shed-spill-spread cascade and mitigate disease risk, b) or if they rather amplify the risk and c) on success factors characterizing restorations that mitigate disease risk. BEPREP will fill this lack in knowledge and provide practical guidance. In spatially and temporally replicated field studies and experiments in case studies in Europe and the tropics, we will study a)-c) and reveal the causal mechanisms of infection dynamics and of drivers along the infect-shed-spill-spread cascade. BEPREP's participatory and transsectorial approach by actively involving indigenous and local communities will enable the identification of success factors of best practice restorations and interventions, incl. nature-based solutions, to guide future biodiversity recovery measures that promote healthy ecosystems. These success factors will contribute to a) interrupt the infect-shed-spill-spread cascade and b) ultimately prevent disease outbreaks. The results of BEPREP help to create a European society prepared and responsive to disease risk. BEPREP will hence accelerate the ecological transition required to meet EU's Biodiversity Strategy for 2030 as a core part of EU's Green Deal and support a green recovery following the COVID-19 pandemic.