Iowa Cochlear Implant Clinical Research Center VII

爱荷华州人工耳蜗临床研究中心七

• 批准号: 10308173
• 负责人: RUTH A BENTLER
• 金额: $ 30.52万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-09-09 至 2023-05-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10308173
• 关键词: Acoustics; Affect; Anatomy; Auditory; Behavior; Cellular Phone; Characteristics; Classification; Clinical Research; Cochlear Implants; Cochlear implant procedure; Cognition; Communication; Data; Decision Making; Detection; Ear; Ecological momentary assessment; Ecology; Environment; Environmental Risk Factor; Exhibits; Goals; Health; Healthcare; Hearing; Hearing Aids; Heterogeneity; Human; Hybrids; Impairment; Implant; Improve Access; In Situ; Individual; International; Intervention; Iowa; Laboratories; Life Style; Literature; Measurement; Mental Depression; Music; Natural Sciences; Noise; Outcome; Outcome Measure; Participant; Patient Self-Report; Perception; Personality; Physiological; Physiology; Policies; Population; Predictive Factor; Principal Investigator; Procedures; Quality of life; Questionnaires; Rehabilitation therapy; Research; Residual state; Role; Signal Transduction; Social Environment; Social Sciences; Social isolation; Socialization; Sound Localization; Speech; Speech Perception; Speech Sound; Standardization; Stimulus; System; Time; Work; base; built environment; design; disability; experience; genetic information; group intervention; hearing impairment; improved; instrument; interest; intervention effect; lexical processing; novel; preservation; primary outcome; programs; social; speech in noise; success; tool

Program Director/Principal Investigator (Last, First, Middle): Gantz, Bruce J. PROJECT SUMMARY – PROJECT 1 The past 35 years of cochlear implant (CI) research have focused on outcomes primarily related to speech perception. Candidacy recently has extended into the less severely impaired population due to newer, shorter implants, including hybrid (acoustic-plus-electric) designs. The potential for improvement/change in domains other than speech perception can inform both policy and rehabilitative decision-making. Human ecology describes the relationship between humans and their natural, social, and built environments. This concept considers that human behaviors must be studied from both the social and natural science vantage points. In hearing health care, success with intervention is as much related to the anatomy/physiology of the individual as it is to the environmental and personal (i.e., ecological) factors that make each individual unique from the next. The overall goal of this project is to determine the impact of intervention on user's hearing-related functions and disability in their natural environments (i.e., real-world outcomes) and to clarify what ecological factors, as well as perceptual factors, affect these real-world outcomes. To date most cochlear implant (CI) research has focused on determining the effect of anatomical and physiological factors on laboratory outcomes, such as speech perception. We recognize, however, that the real-world outcomes exhibit great heterogeneity, which is likely due, in part, to the broader range of environmental and personal contextual (i.e., ecological) underpinnings in the hearing impaired population. As has been the case with hearing aids (HA), much variance can be accounted for by examining individual ecological factors. Very little is understood about (1) the characteristics of ecological factors of the CI population, (2) the influence that ecological factors have on the heterogeneity of real-world outcomes of this population, and (3) how this influences changes over time. With the expanded indications for CI quantifying the ecological factors that parlay into real-world outcomes in CI is critical because real-world outcomes ultimately determine societal burden and policy. Furthermore, because traditional retrospective self-reported outcome measures are often subject to recall bias, we will, in addition to standardized questionnaires and a data-logging feature on the processors, use a smartphone-based ecological momentary assessment (EMA) system to capture users' real-time experiences in situ (i.e., in natural environment). This will allow for measurement of the characteristics of listening environments in addition to subjective assessment of listening difficulty/ease. Two Aims have been designed to study the influence of ecological factors have on outcomes of listeners with a CI. Aim 1. To characterize environmental factors that are relevant to listening and communication for participants in each intervention group (Aim 1A) and to determine the effect of intervention on these factors (Aim 1B). Aim 2. To document the effect of intervention on real-world outcomes (Aim 2A) and determine to what extent environmental, personal, and perceptual factors moderate those outcomes (Aim 2B) over time (Aim 2C).

项目负责人/主要研究者（最后一位、第一位、中间一位）：J. J. J.布鲁斯。 项目摘要-项目1 过去35年的人工耳蜗（CI）研究主要集中在与语音相关的结果 perception.最近，由于更新、更短的 植入物，包括混合（声加电）设计。领域改进/变化的潜力 除了言语感知之外，其他信息可以为政策和康复决策提供信息。 人类生态学描述了人类与自然、社会和建筑环境之间的关系。 这一概念认为，必须从社会科学和自然科学两个方面来研究人的行为 Vantage位置在听力保健中，干预的成功与解剖学/生理学相关 个人的环境和个人（即，生态）因素，使每个人 独一无二的下一个本项目的总体目标是确定干预对用户的 在自然环境中的听力相关功能和残疾（即，现实世界的结果），并澄清 什么样的生态因素，以及感知因素，会影响这些现实世界的结果。 到目前为止，大多数人工耳蜗（CI）研究都集中在确定解剖学和生物力学的影响上。 生理因素对实验室结果的影响，如言语感知。然而，我们认识到， 现实世界的结果表现出很大的异质性，这可能部分是由于更广泛的 环境和个人背景（即，生态学）的基础。作为 助听器（HA）的情况就是如此，通过检查个体， 生态因素目前对生态因子的研究还不多， 人口，（2）生态因素对这一现实世界结果的异质性的影响 人口，以及（3）这如何影响随着时间的推移而变化。随着CI适应症的扩大， 在CI中将生态因素转化为现实世界的结果是至关重要的，因为现实世界的结果最终 决定社会负担和政策。此外，由于传统的回顾性自我报告结果 除了标准化问卷和数据记录之外，测量方法往往会受到回忆偏见的影响，我们还会 功能，使用基于智能手机的生态瞬时评估（EMA）系统， 现场捕捉用户的实时体验（即，自然环境）。这将允许测量 除了对听力难易度的主观评估之外，还可以评估听力环境的特征。两 目的是研究生态因素对CI听众结果的影响。 目标1。描述与参与者的倾听和沟通相关的环境因素 在每个干预组（目标1A），并确定干预对这些因素的影响（目标1B）。 目标二。记录干预对现实世界结局的影响（目标2A），并确定其程度 环境、个人和感知因素随着时间的推移（目标2C）调节这些结果（目标2B）。