The HIV Nexus Scholars Program: A Research Education Program for Early-Stage Investigators Working at the Intersection of Biomedical, Social/Behavioral, and Clinical Science

项目摘要 此应用程序支持在大学推出创新的艾滋病毒Nexus学者计划 加州，旧金山弗朗西斯科（UCSF），NIAID PAR-20-289。该计划将利用丰富的基础设施， 培训，研究和专业知识，以解决2019/2020年艾滋病办公室的交叉，高度优先领域 研究（OAR）战略计划和NIAID使命，包括最先进的生物医学， 社会/行为和临床科学;健康不公平研究;以及培训和多样化的研究 进行高度优先的艾滋病毒研究的工作人员。我们的计划将提供三年的教育，研究， 经验，并指导来自外部机构的早期研究人员（ESI）， 获得R 01级别的资金，但他们表现出致力于改善美国边缘化人群的健康 社区（例如，种族、族裔、性和性别少数群体）受艾滋病毒影响的比例过高， 在生物医学，社会/行为和临床科学的交叉点发起创新研究。科学家 来自或与受影响最大的社区有密切联系的人往往最有能力领导研究， 满足受影响人口的具体需求，符合2019/2020年办事处的目标 艾滋病研究战略计划和迫切需要在艾滋病毒研究管道中培养不同的学者。 Nexus学者计划的核心是一个为期六周的密集年度培训机构， 学者们在加州大学旧金山分校居住了连续三个夏天，在那里他们经常与导师见面， 与其他研究人员联系，参加技能发展短期课程/研讨会，发展和 实施应用研究经验计划，构思和编写NIH资助申请。等 培训将为下一代准备继续和 超过了最近结束艾滋病毒流行病的势头，特别是在社区中， 影响。

PROJECT SUMMARY This application supports the launch of the innovative HIV Nexus Scholars Program at the University of California, San Francisco (UCSF) under NIAID PAR-20-289. This program will leverage a rich infrastructure of training, research, and expertise to address cross-cutting, high-priority areas in the 2019/2020 Office of AIDS Research (OAR) Strategic Plan and NIAID mission, including the integration of state-of-the-art biomedical, social/behavioral, and clinical science; health inequities research; and training and diversifying the research workforce to conduct high-priority HIV research. Our program will provide three years of education, research experiences, and mentoring to early-stage investigators (ESIs) from outside institutions who have not yet attained R01-level funding, but who demonstrate a commitment to improving the health of U.S. marginalized communities (e.g., racial, ethnic, sexual, and gender minorities) disproportionately affected by HIV, and are initiating innovative research at the intersection of biomedical, social/behavioral, and clinical science. Scientists from or closely connected to the most impacted communities are often best positioned to lead research that addresses the specific needs of the affected populations, consistent with the objectives of the 2019/2020 Office of AIDS Research Strategic Plan and the critical need to foster diverse scholars in the HIV research pipeline. The centerpiece of the Nexus Scholars Program is an intensive six-week annual training institute in which Scholars are in residence at UCSF for three consecutive summers, where they meet frequently with mentors, connect with other researchers, participate in skills-development short courses/seminars, develop and implement applied research experience plans, and conceptualize and write NIH funding applications. Such training will provide a foundation for the next generation of HIV researchers who are prepared to continue and outpace the recent momentum to end the HIV epidemic, particularly in communities disproportionately affected.