The HIV Nexus Scholars Program: A Research Education Program for Early-Stage Investigators Working at the Intersection of Biomedical, Social/Behavioral, and Clinical Science

项目总结 该应用程序支持在华盛顿大学启动创新的HIV Nexus学者计划 加州，旧金山(加州大学旧金山分校)，符合NIAID PAR-20-289。该计划将利用丰富的基础设施 培训、研究和专门知识，以处理2019/2020年艾滋病办公室的交叉、高优先领域 研究(OAR)战略计划和NIAID任务，包括整合最先进的生物医学， 社会/行为和临床科学；健康不平等研究；以及培训和使研究多样化 工作人员进行高度优先的艾滋病毒研究。我们的项目将提供三年的教育、研究 经验，以及对尚未从外部机构获得的早期调查人员(ESIS)的指导 获得了R01级的资金，但他们表现出了改善美国边缘人群健康的承诺 受艾滋病毒影响不成比例的社区(例如，种族、族裔、性和性别少数)，并 在生物医学、社会/行为科学和临床科学的交叉点发起创新研究。科学家 来自受影响最大的社区或与其关系密切的社区通常最适合领导以下研究 满足受影响人口的具体需求，符合2019/2020年办事处的目标 他强调了艾滋病研究战略计划的重要性，以及在艾滋病毒研究领域培养不同学者的迫切需要。 Nexus学者计划的核心是一个为期六周的强化年度培训机构，在那里 学者们连续三个夏天住在加州大学旧金山分校，在那里他们经常与导师见面， 与其他研究人员联系，参加技能发展短期课程/研讨会，开发和 实施应用研究体验计划，构思和撰写NIH资金申请。是这样的 培训将为下一代艾滋病毒研究人员提供基础，他们准备继续和 超越最近结束艾滋病毒流行的势头，特别是在不成比例的社区 受影响。

PROJECT SUMMARY This application supports the launch of the innovative HIV Nexus Scholars Program at the University of California, San Francisco (UCSF) under NIAID PAR-20-289. This program will leverage a rich infrastructure of training, research, and expertise to address cross-cutting, high-priority areas in the 2019/2020 Office of AIDS Research (OAR) Strategic Plan and NIAID mission, including the integration of state-of-the-art biomedical, social/behavioral, and clinical science; health inequities research; and training and diversifying the research workforce to conduct high-priority HIV research. Our program will provide three years of education, research experiences, and mentoring to early-stage investigators (ESIs) from outside institutions who have not yet attained R01-level funding, but who demonstrate a commitment to improving the health of U.S. marginalized communities (e.g., racial, ethnic, sexual, and gender minorities) disproportionately affected by HIV, and are initiating innovative research at the intersection of biomedical, social/behavioral, and clinical science. Scientists from or closely connected to the most impacted communities are often best positioned to lead research that addresses the specific needs of the affected populations, consistent with the objectives of the 2019/2020 Office of AIDS Research Strategic Plan and the critical need to foster diverse scholars in the HIV research pipeline. The centerpiece of the Nexus Scholars Program is an intensive six-week annual training institute in which Scholars are in residence at UCSF for three consecutive summers, where they meet frequently with mentors, connect with other researchers, participate in skills-development short courses/seminars, develop and implement applied research experience plans, and conceptualize and write NIH funding applications. Such training will provide a foundation for the next generation of HIV researchers who are prepared to continue and outpace the recent momentum to end the HIV epidemic, particularly in communities disproportionately affected.