Microphysiological Systems World Summit

微生理系统世界峰会

• 批准号: 10318371
• 负责人: Thomas Hartung
• 金额: $ 14.97万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-15 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10318371
• 关键词: 3-Dimensional; Academia; Achievement; Animals; Architecture; Area; Asia; Automobile Driving; Basic Science; Berlin; Biological Sciences; Biology; Biomedical Engineering; Biosensor; Biotechnology; Cells; Chemicals; Clinical Research; Coculture Techniques; Collaborations; Communication; Communities; Development; Drug toxicity; Educational workshop; Europe; Fostering; Functional disorder; Gap Junctions; Generations; Goals; Human; In Vitro; Industrialization; Industry; Interdisciplinary Study; International; Life; Maps; Methodology; Methods; Microfluidics; Modeling; Organ; Outcome; Persons; Pesticides; Pharmaceutical Preparations; Physiology; Process; Psychological Transfer; Research Personnel; Science; Scientist; Series; Societies; Standardization; Statutes and Laws; System; Systems Development; Technology; Testing; Time; Toxicity Tests; Training and Education; Update; base; bioprinting; consumer product; drug development; human model; interest; meetings; microphysiology system; novel strategies; organ on a chip; pre-clinical research; research clinical testing; scaffold; stem cell technology; symposium; tool; translational impact; virtual

Project Summary: Microphysiological systems (MPS) comprise a number of bioengineering breakthroughs that reproduce organ architecture and function in vitro. Fueled by stem cell technologies, a broad variety of especially human models and test systems have emerged, which make relevant experimental tools broadly available through international and multi-disciplinary collaborations. Conference(s) (series) are a key tool to form a community and accelerate scientific developments, their implementation and global harmonization. They provide an overview on the state- of-the-art in such dynamic and diverse fields, enabling transfer learning. A global conference on MPS was identified by opinion leaders in the field as a key step forward in the maturation and harmonization of the area. More than 30 International organizations and companies have teamed up for this proposal to initiate a series of annual MPS World Summits to present the latest scientific achievements, discuss the advances and challenges, and enable communication between young and newly interested scientists and pioneers of the MPS field. The conference should be a kick-off for an International MPS Society. Bringing together the stakeholders from different areas (developers, life scientists, regulators and regulated industry) will allow us to move these breakthrough technologies faster toward reliable, standardized, validated and regulatory accepted tools in biomedical sciences. The conferences are planned for New Orleans in May 2022 (hosts Don Ingber & Thomas Hartung), Europe late 2023 (likely in Berlin hosted by Uwe Marx & Marcel Leist) and on the US west coast, late 2024, to reach out more to the Asia-Pacific region (hosted by Elaine Faustman & Thomas Neumann). Each conference will cover the broader aspects of MPS development and application to map the state of this technology and its challenges and opportunities.

项目概要： 微生理系统（MPS）包括许多生物工程突破， 结构和功能。在干细胞技术的推动下， 和测试系统已经出现，这使得相关的实验工具可以通过国际上广泛使用。 多学科合作。会议（系列）是形成社区和加快 科学发展、其实施和全球协调。他们提供了一个关于国家的概述- 在这样的动态和多样化的领域，使转移学习的最先进的。关于MPS的全球会议 实地舆论领袖认为，这是该领域走向成熟和协调的关键一步。 30多个国际组织和公司已经联手为这一建议发起了一系列 每年的MPS世界峰会，介绍最新的科学成就，讨论进展， 挑战，并使年轻和新感兴趣的科学家和MPS的先驱之间的沟通 领域这次会议应该是一个国际MPS协会的开始。将利益攸关方聚集在一起 来自不同领域（开发人员、生命科学家、监管机构和受监管行业）的专家将允许我们将这些 更快地实现可靠、标准化、经验证和监管认可的工具， 生物医学科学会议计划于2022年5月在新奥尔良举行（主持人Don Ingber和托马斯 Hartung），2023年底的欧洲（可能在柏林，由Uwe马克思和Marcel莱斯特主持）和美国西海岸，2023年底 2024年，更多地接触亚太地区（由Elaine Faustman和托马斯诺依曼主持）。每个 会议将涵盖MPS开发和应用的更广泛的方面，以映射这种状态， 技术及其挑战和机遇。