Interoperative Cardiac Tissue Imaging: Implications in Congenital Heart Disease

项目摘要 此多PI应用程序寻求对第一个名为"术中心脏前沿"的同类会议的支持 组织识别"。会议将促进心脏病的治疗，因此与 NHLBI的使命。我们的具体目标是介绍该领域的临床和研究社区， 小儿心脏手术在这一领域的进展。在管理方面取得了巨大进展， 先天性心脏病患儿当我们处理日益复杂的外科手术时， 心脏传导阻滞的风险成比例增加，需要放置起搏器。我们将探讨 可以用于实时组织识别的新兴生物医学仪器和技术， 减轻这种潜在的并发症。会议将聚集各种技术的专家， 目前正在探索用于实时传导组织识别。我们预计，这将刺激关键的 这些技术的思考和临床转化，以帮助防止在手术过程中对传导系统造成损伤。 先天性心脏病的治疗我们的目标是创建一个论坛，介绍和发展新的想法 以及术中心脏组织识别的策略，将科学家、工程师和 先天性心血管内科的临床医生。我们将召集一组演讲者和参与者，包括 在该地区广泛公认的领导者以及年轻的教师和研究人员谁是参与高， 这一领域的高质量研究。发言者将代表临床医生和非临床科学家谁在工作， 心脏外科、病理学、成像、图像处理和电生理学领域。我们将放置特别的 强调妇女、少数种族/族裔和残疾人的参与，从而积极地 支持心血管科学的多样性。通过这次会议，我们的目标是提供一个互动的论坛， 学生，博士后和初级研究人员介绍他们的工作，并与该领域的领导者互动。另外我们 旨在促进初级和代表性不足的少数民族科学家和临床医生之间的互动， 心胸外科、成像、图像处理和病理学领域， 国际调查员在现场。作为第一次这样的会议，我们预计将有80至120人出席 参与者实施后，我们将评估会议，并设想每年举行一次， 邻近心脏手术、心脏移植或介入心脏病学的领先中心。

PROJECT SUMMARY This multi-PI application seeks support for a first of its kind conference titled “Frontiers in Intraoperative Cardiac Tissue Identification”. The conference will promote the treatment of cardiac disease and is thus relevant to the mission of the NHLBI. Our specific objective is to introduce the clinical and research community in the field of pediatric cardiac surgery to advances in this field. There has been enormous progress in the management of children with congenital heart disease. As we tackle the increasing complexity of surgical procedures, there has been a proportionate increase in the risk of heart block necessitating pacemaker placement. We will explore emerging biomedical instrumentation and technologies that can be utilized for real-time tissue identification to mitigate this potential complication. The conference will gather experts in the various technologies which are currently being explored for real-time conduction tissue identification. We expect that this will stimulate critical thinking and clinical translation of these technologies to help prevent injury to the conduction system during the repair of congenital heart defects. We aim to create a forum for the presentation and development of new ideas and strategies for intraoperative cardiac tissue identification by bringing together scientists, engineers, and clinicians in congenital cardiovascular medicine. We will gather a group of presenters and participants comprising widely acknowledged leaders in the area as well as younger faculty and researchers who are involved in high- quality research in this field. Speakers will represent both clinicians and non-clinical scientists who work in the fields of cardiac surgery, pathology, imaging, image processing, and electrophysiology. We will place special emphasis on the participation of women, racial/ethnic minorities, and persons with disabilities, thereby actively supporting diversity in cardiovascular science. With this conference, we aim to provide an interactive forum for students, postdocs, and junior investigators to present their work and interact with leaders in the field. Also, we aim to facilitate interactions between junior and under-represented minority scientists and clinicians working in the cardiothoracic surgery, imaging, image processing, and pathology fields with prominent senior and international investigators in the field. As a first of a kind conference, we expect an attendance of 80 to 120 participants. After implementation, we will evaluate the conference and envision that it will be held yearly in proximity to leading centers for cardiac surgery, heart transplantation or interventional cardiology.