FASEB's Mobile DNA: Evolution, Diversity, and Impact Conference.

FASEB 的移动 DNA：进化、多样性和影响会议。

• 批准号: 10317953
• 负责人: Victoria Perepelitsa Belancio
• 金额: $ 4万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10317953
• 关键词: Academy; Affect; Age; Aging; Binding Sites; Bioinformatics; Biological Assay; Biological Models; Biological Process; Biology; Biology of Aging; COVID-19 pandemic; Cell Survival; Chronic; Collaborations; Colorectal Cancer; Committee Members; Communication; Communities; Consensus; CpG dinucleotide; DNA Damage; DNA Repair; DNA Sequence Rearrangement; DNA Transposable Elements; Data Set; Development; Diagnosis; Disease; Elements; Ensure; Epigenetic Process; Europe; European; Event; Evolution; Experimental Models; Family Leave; Female; Fostering; Funding; Genes; Genetic; Genetic Variation; Genome; Genomic Instability; Genomics; Germ Lines; Geroscience; Goals; Grant; Health; Human; Human Genome; Immune; Immune response; Individual; Inflammation; Institutes; International; Investigation; Ireland; Leadership; Location; Longevity; Maintenance; Malignant Neoplasms; Minority Participation; Modeling; Mutation; National Institute of Drug Abuse; Nature; Nerve Degeneration; Neurons; Normal tissue morphology; Pathologic; Pathology; Persons; Phenotype; Play; Polyadenylation; Principal Investigator; Process; RNA Processing; RNA Splicing; Recording of previous events; Repetitive Sequence; Research; Research Personnel; Role; Schedule; Science; Scientist; Signal Transduction; Site; Somatic Cell; Source; Students; System; Techniques; Technology; Testing; Thinking; Time; Tissues; Travel; United States National Academy of Sciences; United States National Institutes of Health; age related; base; career; career development; circadian; coronavirus disease; deep sequencing; experience; functional decline; genomic variation; high throughput technology; human disease; improved; innovation; interdisciplinary collaboration; interest; mammalian genome; meetings; member; minority scientist; nervous system disorder; neuronal cell body; normal aging; novel; outreach program; pandemic disease; posters; prevent; programs; promoter; recruit; response; senescence; symposium; tool; transcription factor; transposon/insertion element; trend; virtual

Mobile elements continue to play a major role in restructuring their host genomes. Since the discovery of transposons, the main focus has been on their contribution to germ line diseases, which is proven to be relevant to human health. The major departure of the 2021 FASEB conference from this line of thinking is its focus on the TE contribution to somatic genetic variation and its impact on normal aging and age-associated diseases, specifically those involving transformation or degeneration. Integration of this research direction into the FASEB “Mobile DNA: Evolution, Diversity, and Impact” meeting sets it apart from previous FASEB conferences as well as other TE- and aging-related meetings. Three members of the organizing committee, including the organizer of the conference, are NIA-funded investigators. One member of the committee, Dr. Steven Austad, is a prominent member of the aging field. Four US National Academy of Sciences members and two members of the European Academy of Sciences agreed to present at the conference and participate in the career development and meet-the-expert sessions. Our 2021 FASEB conference was scheduled for June 6-9 in Dublin, Ireland. Having an international location for the first time in the history of this conference is beneficial because both fields are strong in Europe. The European location will also make travel easier (i.e. fewer visa restrictions) and less expensive, which will increase attendance. In response to COVID the FASEB has changed the format to a 2- day virtual conference in June 8-9, 2021, followed by the traditional on-site conference in June 5-9, 2022. This format is beneficial to our goals of establishing and fostering collaborations between the two fields of research.

移动的元素继续在重组其宿主基因组中发挥重要作用。自从发现 转座子，主要的焦点是它们对生殖系疾病的贡献，这被证明是相关的 对人类健康的影响。2021年FASEB会议与这一思路的主要区别在于其重点是 TE对体细胞遗传变异的贡献及其对正常衰老和年龄相关疾病的影响， 特别是那些涉及转化或退化的。将该研究方向纳入FASEB “移动的DNA：进化、多样性和影响”会议也将其与以前的FASEB会议区分开来 与其他TE和老龄化相关的会议一样。组委会三名成员，包括主办方 是由NIA资助的研究人员。委员会的一名成员史蒂文·奥斯塔德博士是一名 老龄领域的杰出成员四名美国国家科学院院士和两名 欧洲科学院同意出席会议并参与职业发展 和专家会议。我们的2021 FASEB会议定于6月6日至9日在爱尔兰的都柏林举行。 在这次会议的历史上第一次有一个国际地点是有益的，因为这两个领域 在欧洲很强大。欧洲的位置也将使旅行更容易（即更少的签证限制）， 价格昂贵，这会增加上座率。为了应对COVID，FASEB将格式改为2- 2021年6月8日至9日举行为期一天的虚拟会议，随后在2022年6月5日至9日举行传统的现场会议。这 这种形式有利于我们在两个研究领域之间建立和促进合作的目标。