A scalable, synthetic retina: signal processing in droplet systems with DNA

该项目旨在设计基于dna的纳米技术来处理合成生物系统中的光信号。该项目的预期结果是开发一个系统的信号转导在人工双层使用新的DNA纳米结构。该项目的预期目标是实现：1)基于光的膜蛋白插入人工双层的控制；2)能够跨膜传递信号的新型dna孔；3)信号处理采用多室生物组分组成。总之，这项技术使我们能够利用光和外部信号来控制合成系统中的生化途径。

This project aims to design DNA-based nanotechnology for processing optical signals in synthetic biological systems. The intended outcome of this project is to develop a system for signal transduction in artificial bilayers using new DNA nanostructures. The anticipated goal of the project is to deliver: 1) light-based control of membrane protein insertion into artificial bilayers; 2) novel DNA-based pores that can transduce signals across membranes; 3) signal processing using multi-compartment biological components composed. Together, this technology allows us to use light and external signals to control biochemical pathways in synthetic systems.