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Clinical Grip Training and Assessment Tool for Rheumatoid Arthritis

Clinical Grip Training and Assessment Tool for Rheumatoid Arthritis
类风湿关节炎的临床握力训练和评估工具
批准号:
10050499
负责人:
金额:
$10.02万
依托单位:
依托单位国家:
英国
项目类别:
Collaborative R&D
财政年份:
2023
资助国家:
英国
项目状态:
已结题
起止时间:
2023 至 --

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中文摘要
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英文摘要
BAM Innovation and Optima Design will co-design a disruptive treatment and monitoring device for rheumatoid arthritis (RA): Grip-RA.There is a desperate need for alternative approaches to support patients with this incurable autoimmune disease affecting \>23m people worldwide, with one-third of people with RA stopping working within five years of diagnosis and the biologic drugs used to manage the condition being extremely expensive, with dosages needing tailoring based on changes in disease activity.This project will design an innovative device which facilitates patient engagement, monitoring and condition management. Grip-RA is envisaged as a physical "stress-ball" style interface, with embedded sensors, offering gold-standard physical rehabilitation benefits, whilst capturing rich objective and patient-reported data to support better condition management for patients and clinicians. Its simple interface will be intuitive, customer-focused, and accessible, including to those with severe RA. Patients and clinicians are calling out for non-smartphone based approaches, which have notoriously poor patient adherence.BAMs two Directors have a personal interest in RA with deep condition specific knowledge, particularly considering the patient perspective.This project will build on this knowledge to design a new class of rehabilitative tool that links patient and clinical practice in a fashion which offers far clearer benefit to the user.Our main objectives are to research both the commercial pull and design feasibility of the Grip-RA product. We will research potential markets in depth. Close engagement with potential clients will inform us about their needs and inform the design process. This will allow us to produce product designs (CAD + model) driven by customer needs (e.g. clinicians/trusts and pharma) and co-developed/assessed by RA sufferers facilitated by the Bath Institute of Rheumatic Diseases charity.BAM will benefit through being able to enter UK/global RA markets, The global rheumatoid arthritis drugs market is significant, projected to reach $63bn by 2027 and presents multiple opportunities to develop partnerships deploying our technology. An example is our proposed exploratory partnership with a leading clinical home-care/specialist pharmacy provider.Key external beneficiaries are clinicians receiving better patient data and patients themselves, who will receive better rehabilitation/treatment reducing suffering and supporting better engagement with society and the economy.
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国内基金
海外基金
肾血管内皮细胞源性外泌体miR-155通过靶向GRIP1调控神经血管单元通讯异常在高尿酸血症认知功能障碍中的机制研究
  • 批准号:
    2026JJ60586
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2026
  • 负责人:
    陈艳芳
  • 依托单位:
青蒿素通过上调GRIP1抑制细胞焦亡拮抗高尿酸血症认知功能障碍
  • 批准号:
    2023JJ60363
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2023
  • 负责人:
    陈艳芳
  • 依托单位:
GRIP1基因在肝癌中的作用和分子机制研究
GLCCI1效应弱化在TNF-α诱导GRIP1解离所致哮喘个体激素敏感性降低过程中的作用机制
  • 批准号:
    81670027
  • 项目类别:
    面上项目
  • 资助金额:
    57.0万元
  • 批准年份:
    2016
  • 负责人:
    冯俊涛
  • 依托单位: