The fluid mechanics of dynamically constricted tubes in pulsatile flow

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This project is aimed at advancing the fundamental understanding of flow instability, the transition to turbulence and the effect on wall shear stress, in a dynamically constricted tube flow. The project will provide the first accurately resolved experimental flow analysis, using tomographic particle imaging velocimetry and 3D laser doppler anemometry, conducted on a novel experimental model, and will resolve, for the first time, turbulence characteristics of the dynamic constriction, using direct numerical simulation with a novel moving boundary implementation. The outcomes will provide the key link between fluid mechanics and wall shear stress, allowing future progress to be made in elucidating the causes of cardiovascular disease.