Identifying Leverage Points to Improve Care of Persons with Alcohol Use Disorder

摘要 该项目的长期目标是进行科学严谨的研究，以确定关键杠杆 改善住院期间酒精使用障碍(AUD)治疗的要点 有助于我的职业发展和向独立研究人员过渡的培训。收到这封信 NIAAA K08奖将让我发展我在进行高级培训时所需的技能和经验 定量分析技术、实施科学方法论以及学术和专业追求。 通过授课课程和研讨会、参加国家会议和辅导相结合 活动，我将获得必要的专业知识，以确保我在K08奖结束时做好准备 以独立调查员的身份在澳大利亚和实施的交汇点执行研究议程 科学。 在实施科学框架的指导下，采用混合方法，研究战略 建议将“大数据”的结果结合起来--包括保险索赔和电子健康记录数据-- 使用来自关键利益相关者的定性数据来确定医院系统内的杠杆点，以增加 实施AUD治疗。建议的项目有以下具体目标：1)审查真实的- 通过酒精相关的急性卫生保健利用来衡量AUD治疗的世界有效性；2)检查 住院期间AUD的患病率及其相关因素；3)使用定量和定性的方法 将数据输入到模型路径，以改进住院期间AUD治疗的实施。 完成这些目标，补充我的培训和职业发展目标，将提供重要的 关于如何改善对澳大利亚糖尿病住院高危人群的护理的信息。

Abstract The long-term goal of this project is to conduct scientifically rigorous research that identifies critical leverage points to improve alcohol use disorder (AUD) treatment during hospitalization while simultaneously acquiring training that facilitates my career development and transition to an independent researcher. Receipt of this NIAAA K08 Award will allow me to develop the skills and experiences I require in conducting advanced quantitative analytic techniques, implementation science methodology, and scholarly and professional pursuits. Through a combination of didactic coursework and workshops, attendance at national meetings, and mentoring activities, I will acquire the expertise necessary to ensure I am well poised at the conclusion of the K08 Award to execute a research agenda as an independent investigator at the intersection of AUD and implementation science. Using a mixed-methods approach informed by an implementation science framework, the research strategy proposes to combine results from “big data”-- including insurance claims and electronic health record data-- with qualitative data from key stakeholders to identify leverage points within the hospital system to increase the implementation of AUD treatment. The proposed project has the following specific aims: 1) examine the real- world effectiveness of AUD treatment as measured by alcohol-related acute health care utilization; 2) examine the prevalence and correlates of AUD treatment during hospitalization; and 3) use quantitative and qualitative data inputs to model pathways for improved implementation of AUD treatment during hospitalization. Completion of these Aims, which complement my training and career development goals, will provide important information on how to improve the care of the high-risk population of hospitalized patients with AUD.