Laboratory-based Approaches to Understanding the Impact of Low Nicotine Content Cigarette Marketing on Young Adults

基于实验室的方法了解低尼古丁含量香烟营销对年轻人的影响

• 批准号: 10352398
• 负责人: Melissa Mercincavage
• 金额: $ 15.33万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-03-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10352398
• 关键词: Accent; Address; Adult; Advertisements; Advertising; Affect; Attention; Behavior; Cigarette; Clinical Trials; Color; Consumption; Data; Dependence; Disease; Educational workshop; Elements; Equipment; Foundations; Future; Goals; Gold; Health; Health Benefit; Health Policy; Health behavior; Image; Industry; Investigation; Knowledge; Laboratories; Laboratory Study; Light; Marketing; Melissa; Mentors; Methodology; Morbidity - disease rate; Nicotine; Perception; Policies; Population; Protocols documentation; Public Health; Randomized; Randomized Controlled Trials; Regulation; Research; Research Activity; Research Design; Research Methodology; Research Project Grants; Risk; Sales; Science; Silver; Smoker; Smoking; Smoking Behavior; Solid; Taste Perception; Tobacco; Tobacco Control Research; Tobacco Industry; Tobacco use; Toxicant exposure; Training; Training Activity; United States Food and Drug Administration; United States National Institutes of Health; Work; authority; base; career; cigarette advertising; cigarette smoking; communication theory; design; efficacy evaluation; experience; health communication; improved; low nicotine content cigarette; mortality; negative affect; non-smoker; novel; pattern perception; primary outcome; public health relevance; risk perception; skills; tobacco advertising; tobacco control; tobacco products; tobacco regulation; tobacco regulatory science; visual tracking; young adult

PROJECT SUMMARY The overall aim of this K07 resubmission is to provide Dr. Melissa Mercincavage with the skills and knowledge to achieve her long-term goal of establishing an independent research career evaluating the impact of novel tobacco product marketing, focusing on young adults. This proposal uses low nicotine content (LNC) cigarettes as an archetypal novel tobacco product to acquire relevant expertise that then can be applied to other products in future research. Dr. Mercincavage's training has given her a solid foundation in health behavior research methodology and tobacco regulatory science specific to nicotine reduction. However, she lacks formal training in health communication theory, marketing research, and clinical trial methodologies. Further, her experience with other aspects of regulatory science, and populations other than adult, daily smokers is limited. The proposed research and training activities, under the guidance of Dr. Andrew Strasser (Mentor), Dr. Joseph Cappella (Co-Mentor), and a committee of tobacco control experts, will address these gaps and enable Dr. Mercincavage to transition to a distinct, independent career. The proposed training plan establishes several objectives to facilitate this transition, including: 1) acquiring knowledge of health communication theory and marketing research methodologies , 2) expanding tobacco regulatory science knowledge to focus on young adult tobacco use, and FDA regulation in general, and as applied to other tobacco products, and 3) obtaining in-depth training in clinical trial methodology. These objectives will be achieved through a combination of formal coursework, seminars and workshops, and directed mentoring activities. The proposed research includes two laboratory-based studies designed to comprehensively address the effects of potential LNC cigarette marketing (i.e., packaging and advertising). The first study will examine the effects of LNC cigarette packaging color on smoking behaviors, risk perceptions, and harm exposure. Young adult smokers (n = 100) will complete a 35-day, 2 x 4 mixed factorial design protocol manipulating nicotine content (between subject: very low vs. intermediate) and pack color (within-subject: own brand vs. white vs. purple vs. black). The second study will examine LNC cigarette advertising content effects on message recall, viewing patterns, and risk perceptions. Young adults (N = 340; 170 smokers, 170 non-smokers) will complete a single laboratory session using a 2 x 2 between-subject design to manipulate advertisement accuracy (true vs. false) and health claim format (implicit vs. explicit). This proposal logically extends Dr. Mercincavage's prior work, and addresses FDA Center for Tobacco Products and NCI Tobacco Control Research Branch priorities to understand effects of tobacco product marketing. Further, this research will inform two distinct, important potential regulatory actions – nicotine reduction and marketing – to reduce the public health burden of tobacco-caused disease , and will culminate in a R01 submission to conduct a randomized controlled trial evaluating the efficacy of specific marketing manipulations (identified through the proposed research) in reducing young adult cigarette use.

项目摘要 K 07重新提交的总体目标是为Melissa Mercincavage博士提供技能和知识 为了实现她的长期目标，建立一个独立的研究生涯，评估小说的影响， 烟草产品营销， 专注于年轻人。该提案使用低尼古丁含量（LNC）香烟 作为一种典型的新型烟草产品，以获得相关的专业知识，然后可以应用于其他产品 在未来的研究中。 博士Mercincavage的训练使她在健康行为研究方面打下了坚实的基础 方法论与烟草监管科学 具体到尼古丁减少。然而，她缺乏正规的训练 在健康传播理论，市场研究和临床试验方法。此外，她的经验 与其他方面的监管科学和人口以外的成年人，每天吸烟者是有限的。 的 在Andrew Strasser博士（导师）、Joseph 卡佩拉（共同导师），和烟草控制专家委员会，将解决这些差距，使博士。 Mercincavage过渡到一个独特的，独立的职业生涯。拟议的培训计划确立了若干 目标，以促进这一转变，包括：1）获得健康传播理论的知识， 市场研究方法 ，2）扩大烟草监管科学知识，重点关注年轻人 成人烟草使用，以及FDA的一般规定，以及适用于其他烟草产品，以及3）获得 临床试验方法学的深入培训。 这些目标将通过以下方式实现： 正式课程、研讨会和讲习班以及指导性辅导活动。拟议研究 包括两项基于实验室的研究，旨在全面解决潜在的LNC的影响 香烟营销（即，包装和广告）。第一项研究将检查LNC香烟的影响 包装颜色对吸烟行为、风险认知和危害暴露的影响。 年轻成人 吸烟者（n = 100） 将完成一项35天、2 x 4混合析因设计方案，操作尼古丁含量（受试者之间： 非常低与中等）和包装颜色（受试者内：自有品牌与白色与紫色与黑色）。第二 研究将探讨LNC香烟广告内容对信息回忆，观看模式和风险的影响 感知 年轻成人（N = 340; 170例吸烟者，170例非吸烟者） 将完成一次实验室会议 使用2 × 2受试者间设计来操纵广告准确性（真与假）和健康声明 格式（隐式与显式）。该提案在逻辑上扩展了Mercincavage博士先前的工作，并解决了FDA 烟草制品中心和NCI烟草控制研究分支优先了解 烟草产品营销。此外，这项研究将告知两个不同的，重要的潜在监管行动 - 减少尼古丁和营销-减少烟草引起的疾病对公共卫生的负担 ，并将 最终提交R 01，进行随机对照试验，评价特定 营销操纵（通过拟议的研究确定），以减少年轻人的香烟使用。