Mentoring and Research in Integrative Medicine

中西医结合的指导和研究

• 批准号: 10350623
• 负责人: Frederick M Hecht
• 金额: $ 18.17万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-03-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10350623
• 关键词: Acupressure; Acupuncture Therapy; Address; Award; Biomedical Research; Biometry; California; Chronic; Clinical; Clinical Sciences; Collaborations; Communication; Creativeness; Data; Diabetes Mellitus; Education; Environment; Faculty; Fellowship Program; Funding; Future; Generations; Goals; Grant; Growth; Health; Institutes; Institution; Integrative Medicine; Interdisciplinary Study; Internist; Intervention; K-Series Research Career Programs; Learning; Link; Measures; Medicine; Mentors; Methodology; Mid-Career Clinical Scientist Award (K24); Modeling; National Center for Complementary and Integrative Health; Obesity; Pain; Peer Review; Play; Postdoctoral Fellow; Prevention; Principal Investigator; Public Health; Publications; Publishing; Research; Research Design; Research Methodology; Research Personnel; Research Project Grants; Resources; Role; Talents; Testing; Time; Training; Translational Research; United States National Institutes of Health; Universities; Work; Workplace; Yoga; adaptive intervention; base; career; career life balance; clinical epidemiology; conflict resolution; design; health disparity; improved; innovation; mindfulness intervention; pain symptom; post-doctoral training; pre-doctoral; professional atmosphere; professor; programs; skills; success; symptom management; symptomatic improvement; therapy development; tool

PROJECT SUMMARY This is a proposed renewal of a highly successful K24 award for Dr. Frederick Hecht, Professor of Medicine at the University of California (UCSF), and director of research at the UCSF Osher Center for Integrative Medicine. Dr. Hecht is an internist with postdoctoral training in clinical epidemiology, who is a leader in research on mindfulness-based interventions and health. He directs the T32-funded UCSF Training in Research in Integrative Medicine (TRIM) fellowship program, and is principal investigator for two NCCIH research grants. He has mentored more than 40 postdoctoral fellows and junior faculty and published over 200 peer-reviewed articles. In the initial K24 period, Dr. Hecht has mentored 12 pre/postdoctoral fellows and 10 junior faculty on K awards. With this K24 renewal, Dr. Hecht aims to mentor at least four postdoctoral and two predoctoral fellows each year, and four to six junior faculty with K awards. He will further develop his research and mentoring capabilities with advanced seminars on research design and biostatistics. UCSF provides an extremely rich and supportive scientific environment for Dr. Hecht's research and that of his mentees, including an outstanding NIH funded CTSA, which is closely integrated with Dr. Hecht's K24 plans. The specific research aims of Dr. Hecht's research program are to: (1) develop and test innovative applications of mindfulness-based interventions and tools for studying the active components of these interventions, (2) assess the mechanisms of action of integrative medicine therapies, and (3) test the benefits of integrative medicine therapies such as acupuncture/acupressure and yoga in decreasing pain and improving symptom management. In this K-24 renewal, Dr. Hecht will continue to focus his research and mentoring on some of our most important chronic health problems, including obesity, pain, and diabetes, applying innovative methodological approaches such as adaptive interventions to optimize integrative medicine based interventions for treatment and prevention of these conditions. With this renewal, he aims to continue providing mentoring and a research environment to develop an exceptionally strong and diverse group of researchers who will play leading roles in the future of integrative medicine research.

项目总结 这是一项非常成功的K24奖的续签建议，授予弗雷德里克·赫克特博士，他是 加州大学洛杉矶分校(UCSF)，加州大学欧舍综合中心研究主任 医学。赫克特博士是一名内科医生，接受过临床流行病学博士后培训，在 正念干预与健康研究。他指导着由T32资助的加州大学旧金山分校的培训 综合医学研究(TRIM)奖学金计划，是两个NCCIH的首席研究员 研究经费。他指导了40多名博士后研究员和初级教员，发表了200多篇论文 同行评议的文章。在最初的K24期间，赫克特博士指导了12名博士后/博士后研究员和10名 获得K奖的初级教员。通过这次K24更新，赫克特博士的目标是指导至少四名博士后和两名博士后 每年都有博士后研究员，以及四到六名获得K奖的初级教员。他将进一步发展他的研究。 并通过研究设计和生物统计学方面的高级研讨会提供指导能力。加州大学旧金山分校提供 为赫克特博士和他的受训者的研究提供了极其丰富和支持的科学环境，包括 美国国立卫生研究院资助的CTSA与赫克特博士的K24计划紧密结合。具体研究 赫克特博士的研究计划的目标是：(1)开发和测试基于正念的创新应用 用于研究这些干预措施的积极组成部分的干预措施和工具，(2)评估机制 以及(3)测试中西医结合疗法的益处，例如 针灸/穴位按摩和瑜伽在减轻疼痛和改善症状管理方面的作用。在这个K-24 更新后，赫克特博士将继续把他的研究和指导重点放在我们最重要的一些慢性疾病上 健康问题，包括肥胖、疼痛和糖尿病，应用创新的方法方法，如 优化基于中西医结合治疗和预防的干预措施的适应性干预 这些条件。通过此次续签，他的目标是继续提供指导和研究环境，以 培养一支非常强大和多样化的研究人员团队，他们将在未来的 中西医结合研究。

项目成果

Targeting of conserved gag-epitopes in early HIV infection is associated with lower plasma viral load and slower CD4(+) T cell depletion.

早期HIV感染中保守的gag表位的靶向与较低的血浆病毒载量和较慢的CD4(+)T细胞消耗有关。

• DOI: 10.1089/aid.2012.0171
• 发表时间: 2013
• 期刊: AIDS research and human retroviruses
• 影响因子: 1.5
• 作者: Perez,CarinaL;Milush,JeffreyM;Buggert,Marcus;Eriksson,EmilyM;Larsen,MetteV;Liegler,Teri;Hartogensis,Wendy;Bacchetti,Peter;Lund,Ole;Hecht,FrederickM;Nixon,DouglasF;Karlsson,AnnikaC
• 通讯作者: Karlsson,AnnikaC

Enhanced Stress Resilience Training in Surgeons: Iterative Adaptation and Biopsychosocial Effects in 2 Small Randomized Trials.

在2个小型随机试验中，外科医生的压力复原力训练增强：迭代适应和生物心理社会影响。

• DOI: 10.1097/sla.0000000000004145
• 发表时间: 2021-03-01
• 期刊: Annals of surgery
• 影响因子: 9
• 作者: Lebares CC;Coaston TN;Delucchi KL;Guvva EV;Shen WT;Staffaroni AM;Kramer JH;Epel ES;Hecht FM;Ascher NL;Harris HW;Cole SW
• 通讯作者: Cole SW

Toward a Compassionate Intersectional Neuroscience: Increasing Diversity and Equity in Contemplative Neuroscience.

• DOI: 10.3389/fpsyg.2020.573134
• 发表时间: 2020
• 期刊: Frontiers in psychology
• 影响因子: 3.8
• 作者: Weng HY;Ikeda MP;Lewis-Peacock JA;Chao MT;Fullwiley D;Goldman V;Skinner S;Duncan LG;Gazzaley A;Hecht FM
• 通讯作者: Hecht FM

Acupressure to Reduce Treatment-Related Symptoms for Children With Cancer and Recipients of Hematopoietic Stem Cell Transplant: Protocol for a Randomized Controlled Trial.

穴位按摩可减少癌症儿童和造血干细胞移植接受者的治疗相关症状：随机对照试验方案。

• DOI: 10.1177/2164956119870444
• 发表时间: 2019
• 期刊: Global advances in health and medicine
• 作者: Lown,EAnne;Banerjee,Anu;Vittinghoff,Eric;Dvorak,ChristopherC;Hartogensis,Wendy;Melton,Alexis;Mangurian,Christina;Hu,Hiroe;Shear,Deborah;Adcock,Robyn;Morgan,Michael;Golden,Carla;Hecht,FrederickM
• 通讯作者: Hecht,FrederickM

Can We Agree What Skilled Mindfulness-Based Teaching Looks Like? Lessons From Studying the MBI:TAC.

• DOI: 10.1177/2164956120964733
• 发表时间: 2020
• 期刊: Global advances in health and medicine
• 作者: S Crane R;Hecht FM;Brewer J;Griffith GM;Hartogensis W;Koerbel L;Moran P;Sansom S;Yiangou A;Kuyken W
• 通讯作者: Kuyken W