Role of type 2 Innate Lymphoid Cells (ILC2s) in optic neuritis

项目总结 本提案请求是一项行政补充，旨在为正在进行的NEI提供基础设施支持 资助RO1研究项目。要求提供资金以更换最初购买的徕卡冷冻器 由NEI基金作为行政补充提供给我们。这是一台标准使用的设备 在大多数分子和细胞生物学研究实验室。4.由于煤气泄漏，修理费将超过 买了一个新的低温恒温器。用最先进的设备取代这个低温恒温器将大大提高 我们的效率成功地实现了母公司RO1赠款中的所有目标。此外，还有另外三个NEI 调查人员(Alexander Ljubimov博士、Mehrnoosh Saghizadeh博士和Yaron Rabinowitz博士)将使用这个低温恒温器 他们的研究。因此，共有9个RO1将使用该仪器进行研究。

PROJECT SUMMARY This proposal request is an Administrative Supplement to provide Infrastructure Support for an ongoing NEI funded RO1 Research Project. Funding is requested to replace a Leica cryostat that was originally purchased by NEI funds that was supplied to us as an Administrative Supplement. This is a standard use piece of equipment in most molecular and cell biology research labs. Due to leaking of gas the cost of repair will be more than buying a new cryostat. The replacement of this cryostat by the stat-of the-art equipment would greatly enhance our efficiency to successfully carry out all of the aims in the parent RO1 grant. In addition, three other NEI investigators (Drs. Alexander Ljubimov, Mehrnoosh Saghizadeh, and Yaron Rabinowitz) will use this cryostat for their research. Thus, a total of 9 RO1 will be using this instrument for their research.