The Luma West Cardiac Detector - A First of Class Device to Diagnose/Exclude Cardiac Arrest with 95% Accuracy & within 5 Seconds, Saving up to 14,700 UK Lives Annually and 1.75m Worldwide.

%20Luma%20West%20Cardiac%20Detector%20-%20A%20First%20of%20Class%20Device%20to%20Diagnose/Exclusion%20Cardiac%20Arrest%20with%2095%%20Accuracy%20

• 批准号: 10056124
• 金额: $ 63.7万
• 依托单位: LUMA WEST LTD
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10056124
• 关键词: Luma; West; Cardiac; Detector; First

Luma West (Luma) is an innovative UK medtech company started by two brothers with medical and engineering expertise. Luma is solving an unaddressed global public health need that could save 1.75m million lives annually (Brouwer, 2015; see appendix 4): a method of rapidly and reliably diagnosing/excluding cardiac arrest.Cardiac arrest is a medical event in which a person's heart stops beating. There are 30,000 out-of-hospital cardiac arrests annually in the UK; only 8% are survived.Chest compressions -- where someone pushes up and down on the chest to pump blood around the body -- are the most important component of advanced life support.Although chest compressions can be life-saving, if the heart suddenly restarts, they break ribs and can cause outflow obstruction. Additionally, inaccurate diagnoses cause delays in appropriate treatment. Accurate, real-time and rapid diagnosis of cardiac arrest is critical according to the 2022 UK Resus Council guidelines.Unfortunately, the only recommended method of diagnosing cardiac arrest is by feeling for a central pulse during short assessments every two minutes (Resus Council, 2022). This is true even in the most state-of-the-art intensive care unit. Peripheral pulses and probes cannot be used as circulation to these areas shut down immediately before/after an arrest. Defibrillators/ECGs also cannot be used as they only measure heart rhythm, not output/function, and heart traces are normal in PEA - the most common out-of-hospital-arrestManual pulse check is incredibly unreliable (Eberle, 1996; Tibballs, 2019). When a pulse is present, 45% of the time it is missed: rib-breaking compressions are continued unnecessarily.When a pulse is absent, 10% of the time one is felt: compressions could be stopped despite being the only thing keeping the patient alive. Pulse check, even by doctors, takes 20--30 seconds (Brouwer, 2015), and survival decreases by 17% for every five-second interruption to compressions.Luma proposes a step-change in the diagnosis of cardiac arrest. This investment will be used to complete proof-of-concept work and prototyping, conduct a clinical trial and commence regulatory approval of a non-invasive diagnostic device suitable for use by non-medics that can, with 95% accuracy, diagnose/exclude cardiac arrest within five seconds. Luma's proposed package of device and training, if widely and publicly disseminated, could save 14,700 lives annually in the UK and 1.75m lives globally, increasing out-of-hospital cardiac arrest survival from 8% to 28% - physiologically possible as Norway has 25% survival of out-of-hospital-arrest.

Luma West（Luma）是一家创新的英国MedTech公司，由两个拥有医学和工程专业知识的兄弟创立。 Luma正在解决未解决的全球公共卫生需求，每年可以挽救175万人的生命（Brouwer，2015年；请参阅附录4）：一种快速可靠地诊断/排除心脏骤停的方法。Cardiaceaciachiaceaciachiaceaciachiac是一个医疗事件，其中一个人的心脏停止跳动。英国每年有30,000次院外心脏骤停；只有8％的人幸存下来。另外，诊断不准确会导致适当的治疗延迟。根据2022年英国复苏委员会指南，准确，实时和快速诊断心脏骤停至关重要。不幸的是，诊断心脏骤停的唯一建议方法是每两分钟在短暂评估中感觉到中央脉搏（Resus Council，20222）。即使在最先进的重症监护室也是如此。外围脉冲和探针不能用作逮​​捕前/之后关闭的这些区域的循环。除颤器/心电图也不能使用，因为它们仅测量心脏节奏，而不是输出/功能，而心脏痕迹在豌豆中正常 - 最常见的省外音次脉冲检查是非常不可靠的（Eberle，1996; Tibballs，2019年）。当存在脉搏时，错过了45％的时间：不必要地继续进行肋骨的压缩。当缺乏脉搏时，感觉到10％的时间：尽管唯一使患者活着的事情，但仍可以停止压缩。脉搏检查，即使是医生，也需要20-30秒（Brouwer，2015年），每五秒钟中断下的生存率下降17％。这项投资将用于完成概念验证工作和原型制作，进行临床试验并开始监管性的非侵入性诊断设备，适合于非医学家使用，该设备可以在五秒钟内以95％的精度诊断/排除心脏骤停。 Luma提议的设备和培训套餐，即使广泛传播，每年可以在英国挽救14,700人的生命，在全球范围内有175万人寿，将院外心脏骤停的存活率从8％增加到28％ - 在生理学上可能是可能的，因为挪威拥有25％的院外侵犯生存。