Modification and Renovation of Vivarium for the Advancement of Institutional Biomedical Research

为促进机构生物医学研究而对动物饲养场进行改造和翻新

基本信息

  • 批准号:
    10374473
  • 负责人:
  • 金额:
    $ 513.07万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2021
  • 资助国家:
    美国
  • 起止时间:
    2021-09-20 至 2025-06-30
  • 项目状态:
    未结题

项目摘要

The proposed project will renovate North Carolina Agricultural and Technical State University’s (NCA&T) 38- year-old vivarium for use as a core research facility serving the university community and the Piedmont Triad region in central NC. This renovation is critically needed to address the vivarium’s structural and design issues that make it challenging to meet the needs of biomedical researchers, a group whose numbers are increasing at our institution. The requested funding will help drive this increase in biomedical research, breaking the Catch-22 predicament that limits faculty submission of federal grant proposals for research with animal subjects and constrains further expansion of our institution’s biomedical research enterprise. As a result of the vivarium’s outdated status, our researchers are using other facilities or changing their research agendas to alternative models. To reverse this trend and align with the university’s strategic plan and stated intent to attain R1 status, the project goals are to (1) renovate and redesign the existing vivarium to provide a modern environmentally-controlled unit, with noise reduction and an efficient cage washing facility and traffic pattern and (2) to create a near barrier facility with fixed exhaust ventilated cages and biological safety cabinets. Long-term impact of the proposed renovation will enable the expansion of biomedical, life science, and agricultural research at NCA&T and the Piedmont Triad region, which is home to a growing number of companies in the biosciences, pharma, and healthcare; and increase the advancement of undergraduate, doctoral and post-doctoral research training to increase regional, statewide and national diversity within biomedical sciences and careers. Renovation of the vivarium will enhance research programs across the institution by providing the resources needed to conduct biomedical research projects on campus in a core research animal facility versus seeking animal housing and ancillary support at other facilities. The renovated facility will also support increased research productivity by encouraging faculty to seek targeted external funding to grow their biomedical research portfolios incorporating animal models and by promoting recruitment of new research faculty with biomedical research interests. Additionally, the project will help us accomplish our long-term goal of achieving AAALAC accreditation. Per the four criteria at U.S.C. 42 Section 283k(c)(2), NCA&T declares its status as an Institution of Emerging Excellence (IEE). The renovated vivarium will help NCA&T elevate its status from an NIH- designated IEE to a research-intensive institution.
该项目将改造北卡罗来纳州农业和技术州立大学(NCA & T) 38-一年的动物园作为核心研究设施,服务于大学社区和 北卡罗来纳州中部的皮埃蒙特三合会地区。这一改造是迫切需要解决的动物园的 结构和设计问题,使其具有挑战性,以满足生物医学研究人员的需求, 在我们的机构里,这个群体的人数正在增加。所要求的资金将有助于推动这一点 生物医学研究的增加,打破了Catch-22困境,限制了教师提交 联邦拨款建议与动物主题的研究和限制进一步扩大我们的 机构的生物医学研究企业。由于动物园的过时的地位,我们的 研究人员正在使用其他设施或改变他们的研究议程,以替代模型。到 扭转这一趋势,并与大学的战略计划和明确的意图,以达到R1的地位, 项目目标是(1)翻新和重新设计现有的动物园,以提供现代化的 环境控制单元,具有噪音降低和高效的笼清洗设施和交通 模式和(2)建立一个近屏障设施,固定排气通风笼和生物安全 橱柜拟议改造的长期影响将使生物医学、生命的扩展成为可能 科学和农业研究在NCA & T和皮埃蒙特三合会地区,这是家庭对越来越多的 生物科学、制药和医疗保健领域的公司数量;并提高 本科,博士和博士后研究培训,以增加区域,全州和 生物医学科学和职业的国家多样性。 动物园的改造将通过提供 在核心研究动物设施中进行校园生物医学研究项目所需的资源 而不是在其他机构寻求动物住房和辅助支持。翻新后的设施还将 通过鼓励教师寻求有针对性的外部资金, 增加其生物医学研究组合,纳入动物模型,并促进招募 具有生物医学研究兴趣的新研究人员。此外,该项目将帮助我们实现 我们的长期目标是获得AAALAC认证。 根据南加州大学的四项标准。42第283k(c)(2)节,NCA & T宣布其作为以下机构的地位: 新兴卓越(IEE)。翻新后的动物园将帮助NCA & T从NIH提升其地位, 指定IEE为研究密集型机构。

项目成果

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