Augmented Reality as an Adjunct to Quitline Counseling for Smoking Cessation

项目概要/摘要 吸烟仍然是美国发病率和死亡率的主要可预防原因。 制定有效的戒烟干预措施仍然是公共卫生的优先事项，移动健康提供了 有机会减少传播和实施戒烟治疗的障碍。该项目将测试 增强现实（AR）的新兴技术，以加强个人戒烟， 联系无烟草佛罗里达戒烟热线获得治疗服务。AR将虚拟物体插入现实世界 在屏幕上看到的环境（例如，智能手机）。线索暴露疗法已经证明有效 在实验室中减少对烟草的渴望，但这些影响似乎并不普遍，远远超出了 消光设置这种灭绝后的“更新效应”在动物和人类身上都得到了证实 问题研究随着AR技术的出现，现在可以在多个国家进行灭绝试验。 吸烟者自己的真实吸烟环境中的环境。可能会延长线索的影响- 接触自然环境为创新和可扩展的戒烟治疗提供了机会， 可以远程管理。在R34治疗开发补助金的资助下，研究小组 已经开发了一个带有基本AR平台的应用程序。重要的是，我们已经测试了应用程序在控制 实验发现，AR刺激满足灭绝线索的关键标准，因为它们：（a）引起 与体内线索相当实质性线索反应性，且（B）对线索的重复暴露减少 渴望（即，灭绝）。拟议项目的主要目标是通过调整 应用程序用于临床，目的是测试AR与quitline治疗联合使用时的疗效，而 还审议了与今后执行工作有关的关键问题。目标1将扩大应用程序是一个迷人的 和用户友好的治疗工具，并协调研究小组之间的所有转介程序 以及“无烟草佛罗里达”的退出热线目标2将从无烟草佛罗里达戒烟热线招募参与者， 随机化个体以仅接收退出线服务或接收退出线服务加上AR应用。 主要结果是登记后6个月时经生化证实的戒烟。目标3将 评估治疗实施问题，以指导未来戒烟线的采用。如果AR应用被证明是 有效，它将准备通过戒烟热线以及其他吸烟方式传播和实施。 戒烟计划（例如，传统戒烟咨询、短信干预、其他移动的 戒烟应用程序）。这项工作有可能为一系列现有的治疗方法提供信息， 依赖，但也适用于其他物质使用障碍和精神健康状况， 条件反射的原则。

PROJECT SUMMARY/ABSTRACT Cigarette smoking remains the leading preventable cause of morbidity and mortality in the United States. Developing effective cessation interventions remains a public health priority, and mHealth offers the opportunity to reduce barriers to dissemination and implementation of cessation treatment. This project will test the emerging technology of augmented reality (AR) to enhance smoking cessation among individuals who contact the Tobacco Free Florida quitline for treatment services. AR inserts virtual objects into the real-world environment as viewed on a screen (e.g., smartphone). Cue-exposure treatments have demonstrated efficacy for decreasing tobacco craving in the laboratory, but these effects do not appear to generalize well beyond the extinction setting. This post-extinction “renewal effect” has been demonstrated in both animal and human studies. With the emergence of AR technology, it is now possible to conduct extinction trials across multiple environments throughout smokers’ own real-world smoking settings. The potential to extend the effects of cue- exposure to naturalistic settings offers the opportunity for an innovative and scalable cessation treatment that can be administered remotely. With funding from an R34 treatment development grant, the research team has already developed an app with the basic AR platform. Importantly, we have tested the app in controlled experiments and found that the AR stimuli satisfied the key criterion for extinction cues in that they: (a) elicited substantial cue-reactivity, comparable to in vivo cues and that (b) repeated exposure to the cues reduced craving (i.e., extinction). The primary goal of the proposed project is to extend this initial work by adapting the app for clinical use, with the objective of testing the efficacy of AR when combined with quitline treatment, while also considering key questions relevant to future implementation. Aim 1 will expand the app to be an engaging and user-friendly treatment tool for smokers, and to coordinate all referral procedures between the study team and the Tobacco Free Florida quitline. Aim 2 will recruit participants from the Tobacco Free Florida quitline and randomize individuals either to receive quitline services only or receive quitline services plus the AR app. The primary outcome is biochemically-confirmed tobacco abstinence at 6 months post-enrollment. Aim 3 will evaluate treatment implementation questions to guide future quitline adoption. If the AR app proves to be efficacious, it will be ready for dissemination and implementation through quitlines as well as other smoking cessation programs (e.g., traditional cessation counseling, text messaging interventions, other mobile cessation apps). This work has the potential to inform a range of existing treatments not only for tobacco dependence, but also for other substance use disorders and mental health conditions that are maintained by principles of conditioning.