Methods Core

方法核心

• 批准号: 10375602
• 负责人: BRIAN Patrick FLAHERTY
• 金额: $ 17.35万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10375602
• 关键词: Acquired Immunodeficiency Syndrome; Applications Grants; Automobile Driving; Award; Behavior; Behavioral; Behavioral Research; Behavioral Sciences; Biometry; Caring; Cellular Phone; Clinical Sciences; Collaborations; Communities; Complement; Complex; Computer software; Consult; Consultations; Data; Data Analyses; Data Collection; Data Set; Development; Educational workshop; Ensure; Epidemic; Ethics; Evaluation; Faculty; Funding; Grant; HIV; Incentives; Intervention; Knowledge; Leadership; Measurement; Mental Health; Mentors; Methodology; Methods; Mission; Modeling; Outcome; Paper; Pattern; Positioning Attribute; Preparation; Process; Publications; Publishing; Qualitative Research; Reproducibility; Research; Research Design; Research Methodology; Research Personnel; Research Support; Resources; Science; Site; Statistical Data Interpretation; Statistical Models; Students; Techniques; Time; Training; Translational Research; Underrepresented Populations; Universities; Visit; Washington; Work; Writing; adaptive intervention; complex data; data management; data visualization; design; experience; improved; innovation; instrumentation; interest; meetings; multidisciplinary; next generation; novel; power analysis; response; skills; statistics; visiting scholar; wearable device

METHODS CORE ABSTRACT Timely support for research design, measurement, statistics, data visualization, and results presentation is essential to ensuring the rigor and reproducibility of D-ARC research and driving scientific innovations. Led by an interdisciplinary team of methodological experts with extensive mentoring and consulting experience, the Methods Core will support a broad range of behavioral research in support of the D-ARC's mission in clinical and translational science. Core Faculty will consult with D-ARC investigators and their collaborators on research methodology across the stages of research, from research planning for a grant, to data collection and analysis, to the presentation and discussion of results. In addition to their need for standard statistical support, investigators are challenged by advances in data collection and statistical models leading to ever more complex data sets and planned analyses; this is especially true for early-stage investigators (ESI). Important recent advances include the management and analysis of dense data resulting from smartphones and wearable devices; adaptive intervention strategies; causal inference for non-randomized interventions; latent variable models capturing and summarizing complex patterns of behavior; nuanced longitudinal models that highlight typical patterns of change as well as variability in patterns of change over time, and the challenges posed by implementing and scaling interventions. Planning such research, as well as analyzing and communicating the results, requires the involvement of expert analytic investigators. The Methods Core Faculty are well equipped to handle these complex types of data, in addition to providing more fundamental statistics support. The aims of the D-ARC Methods Core are to 1) Improve the methodological quality, range, and rigor of behavioral research in mental health and HIV through tailored consultations with D-ARC investigators; 2) Deepen the methodological expertise of D-ARC investigators by offering a quantitatively focused Junior Investigator Group (JIG-Quant) to ESI and funding targeted workshops and visiting scholars on cutting-edge methods; and 3) Stimulate new collaborations among Core Faculty and other experts to propel research on innovative behavioral methods, incentivized by two pilot awards. The Core adds value to the UW research enterprise by contributing to the development of the Next Generation of independent investigators and the creation and application of innovative, rigorous, and reproducible methods. Growing the research workforce and supporting improvements and innovations in methodology will lead to superior science, ultimately exerting a greater impact on the co-occurring mental health and HIV epidemics.

方法核心摘要 及时支持研究设计、测量、统计、数据可视化和结果展示， 这对于确保D-ARC研究的严谨性和可重复性以及推动科学创新至关重要。领导 一个跨学科的方法学专家团队，具有丰富的指导和咨询经验， 方法核心将支持广泛的行为研究，以支持D-ARC的临床使命 和转化科学。核心教师将与D-ARC研究人员及其合作者进行研究咨询 跨研究阶段的方法，从研究计划的赠款，数据收集和分析， 介绍和讨论结果。除了需要标准的统计支助外， 调查人员面临着数据收集和统计模型的进步带来的挑战， 数据集和计划分析;这对于早期研究者（ESI）尤其如此。最近取得的重大 进步包括管理和分析智能手机和可穿戴设备产生的密集数据， 设备;适应性干预策略;非随机干预因果推理;潜变量 捕捉和总结复杂行为模式的模型;细致入微的纵向模型， 典型的变化模式以及变化模式随时间的变化，以及 实施和扩大干预措施。规划这样的研究，以及分析和沟通， 结果，需要专家分析调查人员的参与。方法核心教师装备精良 除了提供更基本的统计支持外，还可以处理这些复杂类型的数据。的目的 D-ARC方法的核心是：1）提高行为研究的方法质量、范围和严谨性 通过与D-ARC调查人员进行有针对性的咨询，在精神健康和艾滋病毒方面取得了进展; 2）深化方法论， D-ARC研究人员的专业知识，提供一个以定量为重点的初级研究人员小组（JIG-Quant）， （c）促进教育、科学和技术服务，并资助关于尖端方法的有针对性的讲习班和访问学者; 核心教师和其他专家之间的合作，以推动创新行为方法的研究， 获得两项飞行员奖励。核心通过为华盛顿大学的研究企业做出贡献， 培养下一代独立调查人员， 严格和可重复的方法。增加研究人员并支持改进， 方法论上的创新将导致上级科学，最终对共生现象产生更大的影响。 心理健康和艾滋病毒流行病。