Methods Core

方法核心

• 批准号: 10569071
• 负责人: BRIAN Patrick FLAHERTY
• 金额: $ 13.03万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10569071
• 关键词: Acquired Immunodeficiency Syndrome; Applications Grants; Automobile Driving; Award; Behavior; Behavioral; Behavioral Research; Behavioral Sciences; Biometry; Clinical Sciences; Collaborations; Communication; Communities; Complement; Complex; Computer software; Consult; Consultations; Data; Data Analyses; Data Collection; Data Set; Development; Educational workshop; Ensure; Epidemic; Ethics; Evaluation; Faculty; Funding; Grant; HIV; Incentives; Intervention; Knowledge; Leadership; Measurement; Mental Health; Mentors; Methodology; Methods; Mission; Modeling; Outcome; Paper; Pattern; Positioning Attribute; Preparation; Process; Publications; Publishing; Qualitative Research; Reproducibility; Research; Research Design; Research Methodology; Research Personnel; Research Support; Resources; Science; Site; Statistical Data Interpretation; Statistical Models; Students; Techniques; Time; Training; Translational Research; Underrepresented Populations; Universities; Visit; Washington; Work; Writing; adaptive intervention; complex data; data management; data visualization; design; experience; improved; innovation; instrumentation; integrated care; interest; meetings; mental health center; multidisciplinary; next generation; novel; power analysis; response; skills; smartphone based device; statistics; visiting scholar; wearable device

METHODS CORE ABSTRACT Timely support for research design, measurement, statistics, data visualization, and results presentation is essential to ensuring the rigor and reproducibility of D-ARC research and driving scientific innovations. Led by an interdisciplinary team of methodological experts with extensive mentoring and consulting experience, the Methods Core will support a broad range of behavioral research in support of the D-ARC's mission in clinical and translational science. Core Faculty will consult with D-ARC investigators and their collaborators on research methodology across the stages of research, from research planning for a grant, to data collection and analysis, to the presentation and discussion of results. In addition to their need for standard statistical support, investigators are challenged by advances in data collection and statistical models leading to ever more complex data sets and planned analyses; this is especially true for early-stage investigators (ESI). Important recent advances include the management and analysis of dense data resulting from smartphones and wearable devices; adaptive intervention strategies; causal inference for non-randomized interventions; latent variable models capturing and summarizing complex patterns of behavior; nuanced longitudinal models that highlight typical patterns of change as well as variability in patterns of change over time, and the challenges posed by implementing and scaling interventions. Planning such research, as well as analyzing and communicating the results, requires the involvement of expert analytic investigators. The Methods Core Faculty are well equipped to handle these complex types of data, in addition to providing more fundamental statistics support. The aims of the D-ARC Methods Core are to 1) Improve the methodological quality, range, and rigor of behavioral research in mental health and HIV through tailored consultations with D-ARC investigators; 2) Deepen the methodological expertise of D-ARC investigators by offering a quantitatively focused Junior Investigator Group (JIG-Quant) to ESI and funding targeted workshops and visiting scholars on cutting-edge methods; and 3) Stimulate new collaborations among Core Faculty and other experts to propel research on innovative behavioral methods, incentivized by two pilot awards. The Core adds value to the UW research enterprise by contributing to the development of the Next Generation of independent investigators and the creation and application of innovative, rigorous, and reproducible methods. Growing the research workforce and supporting improvements and innovations in methodology will lead to superior science, ultimately exerting a greater impact on the co-occurring mental health and HIV epidemics.

方法核心抽象 及时支持研究设计、测量、统计、数据可视化和结果展示 对确保D-ARC研究的严密性和重复性以及推动科学创新至关重要。领头羊 由具有丰富指导和咨询经验的方法论专家组成的跨学科团队 方法Core将支持广泛的行为研究，以支持D-ARC在临床上的使命 和翻译科学。核心学院将与D-ARC调查人员及其合作者就研究进行咨询 研究各个阶段的方法，从赠款的研究规划到数据收集和分析， 介绍和讨论结果。除了他们需要标准的统计支持外， 调查人员受到数据收集和统计模型进步的挑战，这导致了越来越复杂的数据收集和统计模型 数据集和计划分析；对于早期调查人员(ESI)尤其如此。最近的重要事件 改进包括管理和分析由智能手机和可穿戴设备产生的密集数据 设备；适应性干预策略；非随机化干预的因果推断；潜在变量 捕捉和总结复杂行为模式的模型；突出显示的细微差别的纵向模型 变化的典型模式以及随时间变化的变化模式的可变性，以及 实施和推广干预措施。规划这类研究，以及分析和沟通 结果，需要专家分析调查人员的参与。核心教师配备精良的方法 来处理这些复杂类型的数据，此外还提供更基本的统计支持。的目标是 D-ARC方法的核心是1)提高行为研究的方法质量、范围和严谨性 通过与D-ARC调查人员进行量身定制的咨询，在精神健康和艾滋病毒方面；2)深化方法学 通过提供一个专注于量化的初级调查员小组(JIG-Quant)来提高D-ARC调查员的专业知识 ESI和资助有针对性的研讨会和访问学者关于尖端方法；以及3)刺激新的 核心教师和其他专家之间的合作，以推动创新行为方法的研究， 受到两个飞行员奖项的激励。Core通过为UW研究企业增加价值 发展下一代独立调查人员并创造和应用创新的、 严谨、可重复的方法。增加研究人员并支持改进和 方法论的创新将导致卓越的科学，最终对共生产生更大的影响 精神健康和艾滋病毒流行。