Development of Sensitivity to Acoustic Modulation in Infants who use Cochlear Implants
使用人工耳蜗的婴儿对声学调制的敏感性的发展
基本信息
- 批准号:10376052
- 负责人:
- 金额:$ 69.77万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-04-01 至 2026-03-31
- 项目状态:未结题
- 来源:
- 关键词:10 year old4 year old8 year oldAcousticsAddressAdultAgeAuditoryAuditory PerceptionChildChronologyClinicalClinical ManagementCochlear ImplantsCommunicationDevelopmentDevicesEarly InterventionEarly identificationEarly treatmentFrequenciesGoalsHabilitationHearingImplantIndividualInfantInterventionLeadLongitudinal StudiesMeasuresMethodsModificationNoiseOutcomePatientsPatternPerceptionPeripheralProceduresPsychoacousticsResearchResolutionSignal TransductionSpeechSpeech PerceptionSpeech SoundTestingTimeWorkauditory deprivationbasebehavior testclinical carecongenital hearing lossdeafexperienceexperimental studyhearing impairmentimplantationinfancynormal hearingoral communicationpostnatalprogramsskillstemporal measurement
项目摘要
PROJECT SUMMARY/ABSTRACT
The ability of patients with cochlear-implants (CI) to discriminate speech sounds is the fundamental
measure of efficacy that clinicians use to create personalized clinical interventions. Given the universal
importance of early identification and treatment for children born with hearing loss, the most appropriate clinical
intervention for children with CIs should be initiated at the earliest possible age. Despite the routine
implantation of prelingually-deaf infants as young as 9-months-old, there are currently no established clinical
measures of CI efficacy for children younger than approximately 4-years-old. The long-term goal of the
proposed research is to develop new measures of device efficacy in cochlear-implanted infants that can be
used to drive clinical decisions at a much earlier age than is currently possible.
The ability to perceive patterns of temporal or spectral intensity modulation in a noise, or “acoustic
modulation perception”, is known to predict speech understanding in adult CI users. In previous work, the PI
adapted tests of acoustic modulation perception for testing infants and young children. The next step,
proposed in this application, will be to investigate how acoustic modulation perception develops, and relates to
speech perception, in implanted infants. This will involve examining the development of two independent
factors with markedly different trajectories: the ability to resolve the spectral place or timing of modulation, and
sensitivity to intensity modulation across frequency or time. The central hypothesis is that both normal hearing
and implanted infants will show an asymmetry in development of these factors. Frequency and temporal
resolution is expected to mature by 6-months postnatal hearing-age whereas sensitivity to intensity modulation
is expected to remain immature through 7-10 years old. The basis for this hypothesis is that frequency and
temporal resolution reflect early-developing peripheral auditory mechanisms whereas sensitivity to intensity
modulation reflects later-developing central auditory mechanisms.
There are 3 specific aims to this proposal. The first is to characterize the developmental trajectory for
frequency and temporal resolution in implanted and normal hearing infants during the first 6 months of post-
natal hearing experience. The second is to compare the developmental trajectory of spectral and temporal
modulation sensitivity in children implanted during infancy with that of normal hearing children through 10-
years-of-age. The third is to determine if frequency and temporal resolution independently predict speech
perception outcomes in implanted children. This work is a necessary step toward the goal of developing age-
appropriate, nonlinguistic measures of acoustic modulation perception that reflect CI efficacy in implanted
infants. If the long-term goal of the proposed research is realized, the positive impact will be to enable earlier,
more effective, clinical interventions for young patients who use CIs.
项目总结/文摘
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
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David Louis Horn其他文献
David Louis Horn的其他文献
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{{ truncateString('David Louis Horn', 18)}}的其他基金
Development of Sensitivity to Acoustic Modulation in Infants who use Cochlear Implants
使用人工耳蜗的婴儿对声学调制的敏感性的发展
- 批准号:
10207213 - 财政年份:2021
- 资助金额:
$ 69.77万 - 项目类别:
Development of Sensitivity to Acoustic Modulation in Infants who use Cochlear Implants
使用人工耳蜗的婴儿对声学调制的敏感性的发展
- 批准号:
10606617 - 财政年份:2021
- 资助金额:
$ 69.77万 - 项目类别:
Spectral and Temporal Resolution in Infants with Cochlear Implants
人工耳蜗婴儿的频谱和时间分辨率
- 批准号:
8797310 - 财政年份:2014
- 资助金额:
$ 69.77万 - 项目类别:
Spectral and Temporal Resolution in Infants with Cochlear Implants
人工耳蜗婴儿的频谱和时间分辨率
- 批准号:
8630838 - 财政年份:2014
- 资助金额:
$ 69.77万 - 项目类别:
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