Cognitive Training for Diabetes Self-Management

糖尿病自我管理的认知训练

• 批准号: 10375550
• 负责人: Heather Cuevas
• 金额: $ 19.09万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-19 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10375550
• 关键词: Address; Affect; Age; American; Area; Assimilations; Attention; Awareness; Biological; Blood Glucose; Blood Vessels; Calories; Cancer Survivor; Carbohydrates; Chronic; Cognition; Cognitive; Cognitive aging; Cognitive deficits; Complex; Control Groups; Data; Development; Diabetes Mellitus; Diagnosis; Disease; Disease Management; Exhibits; Feasibility Studies; Functional disorder; Glucose; Goals; Heart failure; Home; Hypoglycemia; Hypoglycemic Agents; Impaired cognition; Impairment; Individual; Insulin Resistance; Intake; Intervention; Knowledge; Life; Life Style; Measures; Mediating; Medication Management; Memory; Mission; Monitor; Morbidity - disease rate; Neurocognitive; Neuropsychological Tests; Non-Insulin-Dependent Diabetes Mellitus; Outcome; Participant; Patient Self-Report; Patients; Pattern; Performance; Persons; Pharmaceutical Preparations; Physical activity; Pilot Projects; Prevalence; Problem Solving; Public Health; Randomized; Randomized Controlled Trials; Research; Risk; Role; Sampling; Self Efficacy; Self Management; Short-Term Memory; Technology; Testing; Translating; United States; active control; base; blood glucose regulation; cognitive function; cognitive performance; cognitive process; cognitive rehabilitation; cognitive testing; cognitive training; design; diabetes management; diabetes self-management; efficacy testing; executive function; follow-up; glucose monitor; glycemic control; improved; innovation; insight; mortality; performance tests; pilot test; post intervention; programs; skills; webinar

Abstract The prevalence of both cognitive dysfunction and diabetes is increasing. Research shows that diabetes increases the risk for cognitive impairment and the rate of cognitive decline doubles after diabetes is diagnosed. In turn, cognitive dysfunction can make diabetes self-management more difficult. Diabetes self- management, essential to good glycemic control, requires both the assimilation of knowledge regarding a complex disease and self-management activities such as glucose self-monitoring and medication management. The objective of this R21 application is to pilot test the Memory, Attention, and Problem-Solving Skills for Persons with Diabetes (MAPSS-DM) intervention, a comprehensive cognitive rehabilitation intervention, which will include examining patterns of glycemic variability using continuous glucose monitors (CGMS). The central hypothesis of this proposal is that persons who received the MAPSS-DM intervention will have improved memory and executive function, greater use of compensatory strategies, and improved self- management. We will also explore the role of glucose variability in those changes. The specific aims of this proposal are as follows: Aim 1. To test the efficacy of the MAPSS-DM intervention for improving cognitive function, A1C, and diabetes self-management. Sixty-six participants with cognitive concerns and diabetes will be randomly assigned to either the full MAPSS-DM intervention or an active control. This pilot study will provide estimates of effect size on the following outcomes: A1C, diabetes self-management, and cognitive function. Aim 2. To explore changes in glycemic variability and their association with changes in cognitive function and diabetes self-management. Participants will use continuous glucose monitors pre-, during, and post- intervention to identify changes in glycemic variability related to the intervention. This project is innovative because it will be the first study to test lifestyle-based online cognitive rehabilitation as an intervention in T2DM. Providing cognitive rehabilitation that incorporates a widely available and increasingly acceptable technology (CGMS) is an innovative way to measure the impact of the intervention. This study will fill an important gap by addressing cognitive function in the management of diabetes. The results will contribute to the development of the knowledge necessary to enact strategies to support cognitive function and diabetes self-management which is significant because diabetes is related to accelerated cognitive aging, cognitive deficits are related to poorer self-management, and improvements in cognitive performance as a result of cognitive rehabilitation can translate into improved performance in everyday life and potentially diabetes self-management. Furthermore, the proposed study will offer new mechanistic insights into cognitive function through use of CGMS.

摘要 认知功能障碍和糖尿病的患病率都在增加。研究表明，糖尿病 增加认知损害的风险，糖尿病后认知功能减退率翻一番 诊断出来了。反过来，认知功能障碍会使糖尿病的自我管理变得更加困难。糖尿病患者自身 管理，对于良好的血糖控制是必不可少的，需要吸收关于 复杂的疾病和自我管理活动，如血糖自我监测和用药 管理层。此R21应用程序的目标是初步测试记忆力、注意力和解决问题的能力 糖尿病患者技能(MAPSS-DM)干预--一种全面的认知康复 干预，包括使用连续血糖监测仪检查血糖变异性的模式 (CGMS)。这项建议的中心假设是，接受MAPSS-DM干预的人将 有更好的记忆和执行功能，更多地使用补偿策略，并改善自我 管理层。我们还将探讨葡萄糖变异性在这些变化中的作用。 这项建议的具体目标如下： 目的1.测试MAPSS-DM干预对改善认知功能、A1C和 糖尿病自我管理。66名有认知障碍和糖尿病的参与者将被随机 分配给完全MAPSS-DM干预或主动对照。这项初步研究将提供以下估计 影响大小的结果如下：糖化血红蛋白、糖尿病自我管理和认知功能。 目的2.探索血糖变异性的变化及其与认知变化的关系 功能与糖尿病自我管理。参与者将在治疗前、治疗中和治疗期间使用连续血糖监测仪 干预后，以确定与干预相关的血糖变异性的变化。 这个项目是创新的，因为它将是第一个测试基于生活方式的在线认知的研究 作为对2型糖尿病的干预措施的康复。提供认知康复，结合了广泛可用的 而日益被接受的技术(CGMS)是衡量 干预。这项研究将通过解决认知功能在管理中的作用填补一个重要的空白 糖尿病。这些成果将有助于发展制定战略所需的知识。 支持认知功能和糖尿病自我管理，这一点很重要，因为糖尿病与 认知老化加速，认知缺陷与较差的自我管理能力有关， 认知康复的认知表现可以转化为改善 日常生活和潜在的糖尿病自我管理。此外，拟议的研究将提供新的 通过使用CGMS对认知功能的机械性洞察。

项目成果

Effect of Music Interventions on Cognitive Function in Older Adults With Mild Cognitive Impairment: A Systematic Review.

音乐干预对轻度认知障碍老年人认知功能的影响：系统评价。

• DOI: 10.3928/19404921-20230609-01
• 发表时间: 2023
• 期刊: Research in gerontological nursing
• 影响因子: 1.6
• 作者: Kim,Jeeyeon;Cuevas,Heather;Wood,ShenellTiara
• 通讯作者: Wood,ShenellTiara

The role of cognitive rehabilitation in people with type 2 diabetes: A study protocol for a randomized controlled trial.

• DOI: 10.1371/journal.pone.0285553
• 发表时间: 2023
• 期刊: PLOS ONE
• 影响因子: 3.7
• 作者: Cuevas, Heather;Stuifbergen, Alexa K.;Hilsabeck, Robin C.;Sales, Adam;Wood, Shenell;Kim, Jeeyeon
• 通讯作者: Kim, Jeeyeon