Enhancement of Cancer Research at Clark Atlanta University

克拉克亚特兰大大学癌症研究的加强

• 批准号: 10376107
• 负责人: DAQING WU
• 金额: $ 11.52万
• 依托单位: CLARK ATLANTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10376107
• 关键词: Affect; African American; Age; Animal Experimentation; Area; Awareness; Basic Science; Behavioral; Biological; Biological Sciences; Caliber; Cancer Biology; Caucasians; Cellular biology; Chemistry; Communities; Community Outreach; Core Facility; Development; Disease; Early Diagnosis; Early treatment; Education; Educational Activities; Equipment; Faculty; Faculty Recruitment; Funding; Future Generations; Incidence; Information Dissemination; Infrastructure; Institution; International; Laboratories; Laboratory Research; Malignant Neoplasms; Malignant neoplasm of prostate; Mentors; Mission; Modernization; Molecular; Molecular Biology; Molecular and Cellular Biology; NCI Center for Cancer Research; Pilot Projects; Postdoctoral Fellow; Prevention; Privatization; Program Development; Prostate Cancer therapy; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Research Training; Risk; Schools; Scientist; Students; Teacher Professional Development; Therapeutic; Time; Training; Training and Education; United States National Institutes of Health; Universities; advanced disease; anticancer research; base; biological research; cancer cell; cancer therapy; certificate program; cohesion; combat; community based research; community engagement; drug discovery; graduate student; higher education; infrastructure development; interest; member; men; mortality; next generation; outreach program; program dissemination; programs; prostate cancer progression; racial and ethnic; racial diversity; recruit; research and development; socioeconomics; tenure track; therapeutic development; undergraduate student

Summary Clark Atlanta University (CAU) is a comprehensive, private, urban, coeducational institution of higher education with a predominantly African-American heritage. It offers undergraduate, graduate, and professional degrees as well as certificate programs to students of diverse racial, ethnic, and socioeconomic backgrounds. The Center for Cancer Research and Therapeutic Development (CCRTD) was established at CAU in 1999 with direct support from the NIH/RCMI program. CCRTD faculty was derived from the Departments of Biological Sciences, Chemistry and School of Education with research interests in cancer biology, drug discovery and behavioral aspects of cancer. In 2004, we decided to build a comprehensive research and educational program which will focus on prostate cancer and its impact in the African-American community. In 2005, the Center was designated as CAU's University-wide Center of Excellence to a) develop a core group of internationally known scientists, that will carry-out highly productive basic research in cancer cell biology and molecular biology and contribute in the development of successful therapeutic strategies to combat cancer., b) train undergraduate and graduate students and post-doctoral fellows in the area of cancer biology and, hence, help develop the future generation of African-American scientists of the highest caliber. And c) establish an educational program to increase awareness for prevention, early detection and treatment of cancers, especially those which disproportionately affect the African-American community. As a consequence of targeted recruitment of faculty and staff over the past 12 years, CCRTD is currently one of the largest centers of its kind in the nation with a unique and comprehensive program to combat prostate cancer. We recruited 9 tenure-track faculty members with established expertise in the area of cell and molecular biology of cancer. They established their research programs at CCRTD which focus on understanding molecular mechanisms in the development and progression of prostate cancer and also on the biological basis of higher incidence and development of more advanced disease at an earlier age in African-American men. In order to provide state-of-the art research infrastructure to carry out cutting-edge cell and molecular biology research, CCRTD has developed research core laboratories to support research activities of faculty, staff and students. These core facilities have undergone significant expansion throughout the past several years. We have also been actively engaged in the research training and education of both undergraduate and graduate students in the area of prostate cancer biology. Our community outreach has established dynamic educational and community based research programs which serve the African-American community in the metro Atlanta and beyond. The current proposal seeks to expand and enhance current research and educational activities at CCRTD and will focus on three specific aims. First aim will expand and enhance current research programs in prostate cancer and professional development by supporting three research projects and developing a pilot project program to support junior faculty, investigators and postdoctoral scientists. The second aim will attempt to restructure and modernize research core facilities by consolidating current 8 core research laboratories into 5 core laboratories to create a more efficient research infrastructure. we will also establish a new animal research core laboratory acquire new equipment to upgrade the current research core laboratories. The purpose of the aim 3 will be to create an integrated infrastructure for development of a comprehensive program for dissemination of information and community engagement which will involve local, national and global communities. We will use our current strengths in professional development programs in basic research area, and in the community outreach and educational programs to create this new infrastructure.

概括 克拉克亚特兰大大学（CAU）是一家全面的，私人的，城市的高等教育机构 拥有主要的非裔美国人遗产。它提供本科，研究生和专业学位 以及为各种种族，种族和社会经济背景的学生提供证书计划。中心 癌症研究和治疗发展（CCRTD）于1999年在CAU建立了直接 NIH/RCMI计划的支持。 CCRTD教师源自生物科学系， 化学和教育学院具有癌症生物学，药物发现和行为的研究兴趣 癌症的各个方面。 2004年，我们决定建立一个全面的研究和教育计划 专注于前列腺癌及其对非裔美国人社区的影响。 2005年，该中心被指定 作为CAU在大学范围内的卓越中心a）发展一个核心的国际知名科学家， 这将在癌细胞生物学和分子生物学方面进行高生产力的基础研究，并在 开发成功打击癌症的治疗策略。，b）培训本科生和毕业生 癌症生物学领域的学生和博士后研究员，因此有助于发展未来的一代 口径最高的非裔美国人科学家。 c）建立一个教育计划以增加 对预防，早期发现和治疗癌症的认识，尤其是那些不成比例的癌症 影响非裔美国人社区。由于有针对性地招募教职员工 过去的12年，CCRTD目前是全美最大的中心之一，拥有独特的和独特的 打击前列腺癌的综合计划。我们招募了9名任职教师 在细胞和癌症分子生物学领域建立了专业知识。他们建立了研究 CCRTD的计划，该程序着重于理解开发和发展中的分子机制 前列腺癌以及更高发病率和发展的生物学基础 非洲裔美国男性较早的疾病。为了提供最先进的研究基础设施 进行尖端细胞和分子生物学研究，CCRTD已开发了研究核心实验室 支持教职员工和学生的研究活动。这些核心设施已经发生了重大 在过去的几年中的扩张。我们还积极从事研究培训和 在前列腺癌生物学领域的本科生和研究生的教育。我们的社区 宣传已经建立了动态​​教育和社区研究计划，以服务于 亚特兰大大都会及其他地区的非裔美国人社区。当前的提案旨在扩大和 加强CCRTD的当前研究和教育活动，并将重点关注三个特定目标。第一个目标 将扩大和增强前列腺癌和专业发展的当前研究计划 通过支持三个研究项目并制定一项试点项目计划以支持初级教师 研究人员和博士后科学家。第二个目标将尝试重组和现代化研究 通过将当前8个核心研究实验室合并为5个核心实验室，以创建更多的核心设施 有效的研究基础设施。我们还将建立一个新的动物研究核心实验室将获得新的 升级当前研究核心实验室的设备。目标3的目的是创建一个 用于开发全面计划的综合基础架构，用于传播信息和 社区参与将涉及地方，国家和全球社区。我们将使用我们的电流 基础研究领域的专业发展计划的优势，社区推广和 教育计划，以创建这个新的基础架构。