Enhancement of Cancer Research at Clark Atlanta University

克拉克亚特兰大大学癌症研究的加强

• 批准号: 10376107
• 负责人: DAQING WU
• 金额: $ 11.52万
• 依托单位: CLARK ATLANTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 2024-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10376107
• 关键词: Affect; African American; Age; Animal Experimentation; Area; Awareness; Basic Science; Behavioral; Biological; Biological Sciences; Caliber; Cancer Biology; Caucasians; Cellular biology; Chemistry; Communities; Community Outreach; Core Facility; Development; Disease; Early Diagnosis; Early treatment; Education; Educational Activities; Equipment; Faculty; Faculty Recruitment; Funding; Future Generations; Incidence; Information Dissemination; Infrastructure; Institution; International; Laboratories; Laboratory Research; Malignant Neoplasms; Malignant neoplasm of prostate; Mentors; Mission; Modernization; Molecular; Molecular Biology; Molecular and Cellular Biology; NCI Center for Cancer Research; Pilot Projects; Postdoctoral Fellow; Prevention; Privatization; Program Development; Prostate Cancer therapy; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Research Training; Risk; Schools; Scientist; Students; Teacher Professional Development; Therapeutic; Time; Training; Training and Education; United States National Institutes of Health; Universities; advanced disease; anticancer research; base; biological research; cancer cell; cancer therapy; certificate program; cohesion; combat; community based research; community engagement; drug discovery; graduate student; higher education; infrastructure development; interest; member; men; mortality; next generation; outreach program; program dissemination; programs; prostate cancer progression; racial and ethnic; racial diversity; recruit; research and development; socioeconomics; tenure track; therapeutic development; undergraduate student

Summary Clark Atlanta University (CAU) is a comprehensive, private, urban, coeducational institution of higher education with a predominantly African-American heritage. It offers undergraduate, graduate, and professional degrees as well as certificate programs to students of diverse racial, ethnic, and socioeconomic backgrounds. The Center for Cancer Research and Therapeutic Development (CCRTD) was established at CAU in 1999 with direct support from the NIH/RCMI program. CCRTD faculty was derived from the Departments of Biological Sciences, Chemistry and School of Education with research interests in cancer biology, drug discovery and behavioral aspects of cancer. In 2004, we decided to build a comprehensive research and educational program which will focus on prostate cancer and its impact in the African-American community. In 2005, the Center was designated as CAU's University-wide Center of Excellence to a) develop a core group of internationally known scientists, that will carry-out highly productive basic research in cancer cell biology and molecular biology and contribute in the development of successful therapeutic strategies to combat cancer., b) train undergraduate and graduate students and post-doctoral fellows in the area of cancer biology and, hence, help develop the future generation of African-American scientists of the highest caliber. And c) establish an educational program to increase awareness for prevention, early detection and treatment of cancers, especially those which disproportionately affect the African-American community. As a consequence of targeted recruitment of faculty and staff over the past 12 years, CCRTD is currently one of the largest centers of its kind in the nation with a unique and comprehensive program to combat prostate cancer. We recruited 9 tenure-track faculty members with established expertise in the area of cell and molecular biology of cancer. They established their research programs at CCRTD which focus on understanding molecular mechanisms in the development and progression of prostate cancer and also on the biological basis of higher incidence and development of more advanced disease at an earlier age in African-American men. In order to provide state-of-the art research infrastructure to carry out cutting-edge cell and molecular biology research, CCRTD has developed research core laboratories to support research activities of faculty, staff and students. These core facilities have undergone significant expansion throughout the past several years. We have also been actively engaged in the research training and education of both undergraduate and graduate students in the area of prostate cancer biology. Our community outreach has established dynamic educational and community based research programs which serve the African-American community in the metro Atlanta and beyond. The current proposal seeks to expand and enhance current research and educational activities at CCRTD and will focus on three specific aims. First aim will expand and enhance current research programs in prostate cancer and professional development by supporting three research projects and developing a pilot project program to support junior faculty, investigators and postdoctoral scientists. The second aim will attempt to restructure and modernize research core facilities by consolidating current 8 core research laboratories into 5 core laboratories to create a more efficient research infrastructure. we will also establish a new animal research core laboratory acquire new equipment to upgrade the current research core laboratories. The purpose of the aim 3 will be to create an integrated infrastructure for development of a comprehensive program for dissemination of information and community engagement which will involve local, national and global communities. We will use our current strengths in professional development programs in basic research area, and in the community outreach and educational programs to create this new infrastructure.

总结 克拉克亚特兰大大学（CAU）是一所综合性的私立城市男女同校高等教育机构 主要是非洲裔美国人的血统它提供本科，研究生和专业学位， 以及为不同种族、民族和社会经济背景的学生提供证书课程。中心 癌症研究和治疗开发（CCRTD）于1999年在CAU成立， NIH/RCMI计划的支持。CCRTD的教师来自生物科学系， 化学和教育学院，研究兴趣为癌症生物学、药物发现和行为学 癌症的方面。2004年，我们决定建立一个全面的研究和教育计划， 关注前列腺癌及其对非洲裔美国人社区的影响。2005年，该中心被指定为 作为CAU的大学卓越中心，a）培养一批国际知名的科学家， 该研究所将在癌细胞生物学和分子生物学领域开展高效率的基础研究， 发展成功的治疗策略来对抗癌症，B）培养本科生和研究生 学生和博士后研究员在癌症生物学领域，因此，帮助发展下一代 最优秀的非裔美国科学家c）建立一个教育方案， 提高对癌症的预防、早期发现和治疗的认识，特别是那些 影响了非裔美国人社区由于有针对性地招聘教师和工作人员， 在过去的12年里，CCRTD是目前全国最大的同类中心之一， 治疗前列腺癌的综合方案。我们招募了9名终身教职员工， 在癌症的细胞和分子生物学领域建立了专业知识。他们建立了他们的研究 CCRTD的项目，重点是了解发展和进展中的分子机制 前列腺癌的生物学基础也更高，发病率和发展更先进 在非洲裔美国男性中，这种疾病在较早的年龄发生。为了提供最先进的研究基础设施， 开展尖端的细胞和分子生物学研究，CCRTD已建立研究核心实验室， 支持教职员工和学生的研究活动。这些核心设施经历了重大的 在过去的几年里，扩张。我们还积极参与研究培训， 前列腺癌生物学领域的本科生和研究生教育。我们的社区 外展已经建立了动态的教育和社区为基础的研究计划，服务于 亚特兰大市区及其他地区的非裔美国人社区。目前的建议旨在扩大和 加强CCRTD目前的研究和教育活动，并将侧重于三个具体目标。首要目标 将扩大和加强目前在前列腺癌和专业发展的研究计划 通过支持三个研究项目和开发一个试点项目计划，以支持初级教师， 研究人员和博士后科学家。第二个目标将试图调整研究结构并使之现代化 核心设施，将现有的8个核心研究实验室合并为5个核心实验室， 高效的研究基础设施。我们还将建立一个新的动物研究核心实验室，收购新的 更新现有的研究核心实验室。目标3的目的是创造一个 建立综合性基础设施，以制定全面的信息传播方案， 社区参与，包括地方、国家和全球社区。我们将利用现有的 在基础研究领域的专业发展计划的优势，并在社区外展， 教育项目来创造新的基础设施。