Co-creation of smart socks (MPATIX) with sensors and AI to monitor physiology, understand behaviour and predict problems for people with dementia living in the community

痴呆症的治疗是具有挑战性的，也是昂贵的，在英国花费了350亿英镑。根据人口趋势，在不到30年的时间里，英国痴呆症患者的数量将激增至160万人，这对医疗和社会护理提出了前所未有的需求。在英国目前患有痴呆症的92万人中(阿尔茨海默氏症协会)，大多数(56万人或61%)生活在社区(社会关怀卓越研究所-2020)。这些人中约有一半人经历了与无法管理的痛苦有关的挑战性行为症状(攻击性、焦虑、激动)(Anatchkova-2019年)。阿尔茨海默氏症研究(英国)*在英国的成本超过20亿GB/年(Morris-2015)*反映了可解决的潜在问题，如个人无法沟通的不适/缺乏疼痛管理(Cohen-Mansfield-2000)当照顾者未能识别/解决痴呆症患者的需求时，就会发生痛苦行为，后者通常无法确定或沟通他们陷入困境的原因/(阿尔卡斯-1996)。对于支持照料者迅速响应个人独特需求和情景触发以防止行为升级的技术解决方案的需求尚未得到满足(Martínez-Raga-2018)。正在出现的解决方案现在侧重于使用皮肤电活动来识别刺激的生理前体，从而能够改善管理(Kikhia-2016；Melander-2017/2018)。到目前为止，这些设备使用的是手腕安装的生理传感器。然而，腕式传感器一直难以获得用户/护理者的接受，导致了骚动、耻辱(Hassan-2017)和移除(Bankole-2011)。在阿尔茨海默氏症协会的资助下，Milbotix开发了带有舒适的电子纺织品传感器的MPATIX智能袜子，可以测量脉搏、汗水、温度和运动。利用我们新颖的机器学习算法和移动应用程序，我们可以提醒痴呆症护理人员痛苦的早期迹象，以促进主动/预防管理。MPATIX袜子看起来和感觉都像普通袜子，可以机洗，不需要充电。英国痴呆症研究所(DRI)的Minder平台将传感器和设备连接到临床仪表盘上，已经在改善痴呆症患者的生活。Milbotix与伦敦帝国理工学院英国DRI护理研究与技术中心的合作意味着远程临床医生可以提醒远程临床医生行为和认知/生理状态的变化，这是现有设备无法做到的。在该项目期间进行的用户研究、技术试验和可行性研究将有助于确保MPATIX满足最终用户的需求，并收集痴呆症患者及其社区护理人员受益的证据。

Dementia care is challenging and expensive, costing £35 billion in the UK. Following demographic trends, the number of people living with dementia in the UK will surge to 1.6 million in less than three decades, placing unprecedented demand on health and social care.Of the 920,000 people currently living with dementia in the UK (Alzheimer's Society), the majority (560,000 or 61%) live in the community (Social Care Institute for Excellence-2020). Around half of these people experience challenging behavioural symptoms (aggression, anxiety, agitation) linked to unmanaged distress (Anatchkova-2019).Distressed behaviours:* Are a leading source of burden for carers (Tsai-2021), and factor into families' decisions to place relatives into care homes (Hermann-2006; Alzheimer's Research UK)* Cost over £2 billion/year in the UK (Morris-2015)* Reflect resolvable underlying issues such as discomfort/lack of pain management which the person cannot communicate (Cohen-Mansfield-2000)Distressed behaviours occur when carers fail to recognise/address the needs of people with dementia, who often cannot identify or communicate why/that they are in distress (Algase-1996). There is an unserved need for technological solutions that support carers to promptly respond to individuals' unique wants and situational triggers to prevent escalations in behaviour (Martínez-Raga-2018).Emerging solutions are now focusing on using electrodermal activity to identify the physiological precursors of agitation enabling improved management (Kikhia-2016; Melander-2017/2018). To date these devices have used wrist-mounted physiological sensors. However, wrist-mounted sensors have struggled to gain user/carer acceptance, causing agitation, stigmatisation (Hassan-2017), and removal (Bankole-2011).With funding from Alzheimer's Society, Milbotix has developed MPATIX smart socks with comfortable e-textile sensors that measure pulse, sweat, temperature, and motion. Utilising our novel machine learning algorithm and mobile application, we can alert dementia carers to early signs of distress to promote proactive/preventative management. Looking and feeling like normal socks, the MPATIX socks are machine washable and won't require charging.The UK Dementia Research Institute (DRI) Minder platform connects sensors and devices to a clinical dashboard and is already improving the lives of people affected by dementia. Milbotix's collaboration with the UK DRI Care Research & Technology Centre at Imperial College London means that remote clinicians can be alerted to changes in behaviour and altered cognitive/physiological states, which is not possible with existing devices.User research, a technology pilot and a feasibility study performed during this project will help to ensure that MPATIX meets end users' needs, and collect evidence of benefits for people with dementia and their carers living in the community.