Ensuring medication ingestion without altering existing medication regimen
确保药物摄入而不改变现有的药物治疗方案
基本信息
- 批准号:10384824
- 负责人:
- 金额:$ 49.64万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-15 至 2023-12-31
- 项目状态:已结题
- 来源:
- 关键词:AccidentsAddressAdherenceAgeAlzheimer&aposs DiseaseAssisted Living FacilitiesBullaCOVID-19 pandemicCaregiversCaringChronic DiseaseCommunicationDataDementiaDetectionDevelopmentDisease ManagementDoseDrug PrescriptionsEarly InterventionElderlyEncapsulatedEnsureEnvironmentEventFeedbackFrequenciesGalantamineGenerationsGrantHealth care facilityHearingHomeImpaired cognitionIndividualIngestionInterventionInterviewLong-Term CareMonitorNeckNetwork-basedNursing HomesParticipantPatientsPersonsPharmaceutical PreparationsPhaseRadioReaderRegimenReportingRetirementSignal TransductionSmall Business Innovation Research GrantStomachStructureSymptomsSystemTechnologyTimeaging populationbasecapsulecare costscare providerscloud basedcostdesigndonepezileffectiveness evaluationexperienceimprovedmedication compliancememory caremobile applicationmonitoring devicepillprototyperadio frequencyremote monitoringrepositoryrivastigminesensorsignal processingusability
项目摘要
PROJECT SUMMARY
In the US, approximately 835,000 persons are living in assisted living facilities with more than 50 percent
of those having some form of dementia or cognitive impairment. The average cost of those living in assisted
living facilities is $4050 per month, with memory care increasing this cost by an average of $1250 per month.
Advancements in medications such as Donepezil, Galantamine, and Rivastigmine have been shown to help
manage and even reverse some dementia symptoms, but these medications are not effective unless they are
taken on a regular basis. Slowing the progression of dementia can prolong the ability of persons to live
independently. While the use of blister packs and pill boxes are designed to help ensure that patients are taking
medications on a prescribed basis, these technologies report intent to ingest and often do not provide any
feedback that can be monitored by others outside the home. Given that 53 million US citizens are already past
retirement age and that 70 percent will require some form of long-term care in their lifetime, it is clear that the
cost of managing this disease will continue to grow unless alternative solutions are put in place.
In Phase I of the grant we propose to enhance the FDA cleared ID-Cap system by building a home-based
ingestion monitoring system that can detect medication ingestions within the home instead of requiring a user to
wear an ID-Cap Reader. The ID-Cap system is currently designed to detect ingestions by sending out a small
radio signal from within a person's stomach when an ID-Cap is ingested. The existing system detects these
signals using a lanyard-style reader. As these patients may forget to use the reader, we propose to create a
new reader design that can “hear” the ingestion from across the room using improvements in antenna design
and signal processing. To ensure detection if a patient takes their medication in different rooms, a mesh network
of readers placed in the home can ensure that the signal is detected and forwarded to the existing cloud-based
monitoring platform. In Phase I, we propose two specific aims.
Aim 1 – Create a prototype wall-plug based networked reader
Leveraging our experience developing the existing ID-Cap wearable reader, we will design a new generation
reader that will be able to detect ingestions within a room instead of requiring the user to wear a reader. The
captured signals will be forwarded across a mesh network to a base station that ensures delivery to a cloud
repository so that care providers can monitor actual ingestion events and intervene if needed.
Aim 2 – Evaluate effectiveness and acceptability of the new system in 3 simulated environments
Using the prototyped base station and networked readers, we will evaluate the ability to detect signals in three
different home configurations. This feedback will help inform installation configuration designs regarding the
optimal number and placement of readers. Interviews with persons with dementia and their caregivers will inform
acceptability.
项目总结
项目成果
期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
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Tony Chris Carnes其他文献
Tony Chris Carnes的其他文献
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{{ truncateString('Tony Chris Carnes', 18)}}的其他基金
Fast-Track Multimodal monitoring for neonatal neurocritical care
新生儿神经重症监护的快速多模式监测
- 批准号:
10601201 - 财政年份:2023
- 资助金额:
$ 49.64万 - 项目类别:
ID-Cap System: Next generation ingestible sensors for medication adherence measurement
ID-Cap 系统:用于药物依从性测量的下一代可摄入传感器
- 批准号:
10475453 - 财政年份:2022
- 资助金额:
$ 49.64万 - 项目类别:
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