Improving physical function and quality of life in older adults with prediabetes utilizing interactive small-group resistance training through video conference technology

通过视频会议技术利用交互式小组阻力训练，改善患有前驱糖尿病的老年人的身体功能和生活质量

• 批准号: 10384566
• 负责人: Eric Levitan
• 金额: $ 30万
• 依托单位: IMPACTIV, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-15 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10384566
• 关键词: Accountability; Adherence; Adult; Affect; Age; Behavioral; Benchmarking; Body Weight; Chronic Disease; Client; Clinical Trials; Cognition; Cognitive; Communities; Computer software; Couples; Custom; Databases; Elderly; Electronic Mail; Elements; Equilibrium; Exercise; Exertion; Family; Family member; Feedback; Friends; Glucose; Glycosylated hemoglobin A; Goals; Health; Hour; Independent Living; Individual; Internet; Joints; Knee; Location; Lower Extremity; Measures; Monitor; Motivation; Motor; Movement; Muscle; Muscle function; Muscular Atrophy; Non-Insulin-Dependent Diabetes Mellitus; Outcome; Participant; Performance; Persons; Phase; Physical Function; Physiological; Pilot Projects; Prediabetes syndrome; Quality of life; Sampling; Silver; Small Business Innovation Research Grant; Social Network; Social support; Supervision; Support System; System; Technology; Testing; Thinness; Time; Training; Training Programs; Videoconferencing; Waiting Lists; Woman; Work; aging in place; arm; base; cognitive task; commercialization; design; digital; effectiveness evaluation; evidence base; exercise program; experience; fall risk; fitness; healthy aging; improved; in vivo; innovation; member; mobile application; muscle form; novel; pandemic disease; prevent; primary outcome; prototype; psychologic; sarcopenia; satisfaction; secondary outcome; sedentary; social engagement; strength training; success; technological innovation; usability; virtual; walking speed; young adult

Vivo is a virtual small group exercise program designed for adults 55 and over that is unique in the increasingly popular digital fitness market. Vivo offers 3 key market differentiators: 1) a personalized and individualized live training experience with feedback from a certified trainer, 2) a community of older adult exercisers which enhances motivation and social support, and increase accountability and fun, and 3) the Vivo training experience focuses on improving physical function using performance feedback, goal setting, and a system to measure perceived exertion. Most older adults experience a 30% loss in muscle mass between ages 50–70. Resistance training is the most effective strategy for improving both muscle mass and function and managing sarcopenia. Vivo’s programming is based on the scientific evidence that even in the absence of chronic disease, resistance training that is customized to meet the individual’s needs and level of functioning is a feasible and evidence-based approach to improve physical function, regulate glucose handling, reduce the risk for falls, and prolong independent living and aging in place. To date 92 people have participated in Vivo (age range 44-93). In our pilot study of 34 older adults (74% women; mean age 70.9 y; range 60-84y) after 8 weeks of participating in Vivo with a certified trainer (average of 12 hours of training per person) we observed +25.8% improvement in upper body strength as measured by the 30 second arm curl test; +25.9% improvement in lower body strength as measured by the 30 second chair stand test; and +28% improvement in endurance as measured by the 2-minute knee raise test. The aims for this SBIR FastTrack are as follows: Phase I Aim 1: Evaluate the acceptability, feasibility, and fidelity of current Vivo prototype in sedentary older adults with prediabetes Milestone 1: Assess a) attendance, benefits and barriers/facilitators of participation; b) ease of use; and c) overall satisfaction. Milestone 2: Assess trainer fidelity. Aim 2 : Design and develop a multifunctional platform prototype for Vivo 2.0 Milestone 1: Create functional specifications of the client-centered approach (results, goals, adherence, upcoming workouts), and social engagement and support. Milestone 2: Develop a clickable prototype of the platform. Phase II Aim 1: Design and build the Vivo 2.0 platform – a unified web/mobile application. Milestone 1: Assess prototype usability. Milestone 2: Iterate the design on the software and hardware to increase usage, accuracy and usability. Milestone 3: Develop and test a minimum viable software product based on the new prototype and functional design to include a mobile front-end and web front-end app and a backend database. Aim 2: Conduct a RCT to determine effectiveness of Vivo 2.0 v. wait list control. Primary outcomes will be change in lower extremity strength after 12 weeks measured by the number of chair stands in 30 seconds and average glycemic level (HgA1c). Secondary outcomes will include improvements in quality of life, and effect of adherence and social engagement on physical function outcomes.

Vivo是专为55岁及以上的成年人设计的虚拟小组锻炼项目，是独一无二的