Improvements to the Regional Biocontainment Research Facilities at the University of Missouri

密苏里大学区域生物防护研究设施的改进

• 批准号: 10394455
• 负责人: Christian L. Lorson
• 金额: $ 332.73万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-23 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10394455
• 关键词: Air; Animals; Area; Arthropods; Carbon Dioxide; Communication; Containment; Contractor; Decontamination; Elevator; Equipment; Gases; Hydrogen Peroxide; Immunology; Information Technology; Liquid substance; Maintenance; Mechanics; Missouri; Modernization; Nitrogen; Philosophy; Safety; Security; Series; Steam; System; Universities; Vacuum; Walking; cost; improved; repaired; research facility

PROJECT SUMMARY/ABSTRACT The central philosophy we used in approaching this opportunity was to not include items of routine maintenance or repair, which are currently provided by our experts in facilities management. Instead, we have focused on subsystem repairs or upgrades that are considered “betterments”. Betterments are not routinely performed by facility management without an associated cost or without going through an external contractor. Therefore, the scope of our proposal is limited to facility betterments. Broadly, the betterments (or what we need) are divided into three major subareas as listed below while additional technical details are provided in the Modernization Plan. We have identified a series of high priority targets and each request is detailed within the following sections. SPACES: REMODELING OF ARTHROPOD CONTAINMENT SUITE, ANIMAL ROOMS, CHANGE ROOMS AND ROOF SYSTEM. Renovations of our change room spaces, replacement of the flat room section above our security office and breakroom, painting and drywall repairs in our mechanical spaces, upgrades of our ABSL3 space with Arcoplast ceilings and renovations to our arthropod containment suite. FACILITY SUBSYSTEM UPGRADES/BETTERMENTS. Briefly, these subsystems include the following: an elevator, upgrades to our outer fence and gates, security server and camera upgrades, upgrades to our Phoenix valves and Metasys controllers, upgrades to our steam boiler burner systems, gas system upgrades including liquid nitrogen, CO2, house vacuum and compressed air subsystems, and addition of a new suite communication system. REPLACEMENT/BETTERMENT OF CORE EQUIPMENT. To support the functionality and safety of the improved facility we have requested and identified several pieces of equipment. Requested equipment includes a new effluent decontamination system (EDS), 4 class II biosafety cabinets; 2 vaporous hydrogen peroxide area decontamination systems; upgrades/replacements for the Immunology Core and Aerobiology Core; information technology core improvements; and 2 walk-in arthropod environmental chambers.

项目摘要/摘要 我们在接近这一机会时使用的中心哲学是不包括例行项目 维护或维修，目前由我们的设施管理专家提供。相反，我们 专注于被认为是“改善”的子系统维修或升级。改善不是 设施管理通常没有相关成本或不经过外部 承包商。因此，我们的提案范围仅限于设施的改善。从广义上讲，改善了 （或我们需要的）分为三个主要的次级群岛，如下所示，而其他技术细节 我们已经确定了一系列高优先级目标，每个请求 在以下各节中详细介绍。 空间：节肢动物遏制套件，动物室，换室和 屋顶系统。更换房间的翻新工程，更换我们上方的平坦房间部分 安全办公室和休息室，我们的机械空间中的绘画和干墙修理，我们的升级 ABSL3空间，带有Arcoplast天花板和对节肢动物遏制套件的翻新。 设施子系统升级/改善。简而言之，这些子系统包括以下内容： 升升，升级到我们的外栅栏和门，安全服务器和摄像机升级，升级到我们的 凤凰阀和Metasys控制器，升级到我们的蒸汽锅炉燃烧器系统，气体系统升级 包括液氮，二氧化碳，房屋真空和压缩空气子系统以及新套件的添加 通信系统。 核心设备的更换/改善。支持 改进的设施我们已要求并确定了几件设备。请求的设备 包括一个新的废水净化系统（EDS），4个II类生物安全柜； 2个蒸发氢 过氧化物区域净化系统；免疫学核心和特技生物学的升级/替代品 核;信息技术核心改进；和2个步入式节肢动物环境室。