Green deal inspired correlative imaging-based characterization for safety profiling of 2D materials (ACCORDs)

绿色协议激发了基于相关成像的二维材料安全分析表征（ACCORD）

• 批准号: 10062844
• 金额: $ 32.94万
• 依托单位: HAYDALE LIMITED
• 依托单位国家: 英国
• 项目类别: EU-Funded
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10062844
• 关键词: Green; deal; inspired; correlative; imaging

ACCORDs will develop an imaging-based characterization framework (ACCORDs framework) for the holistic correlative assessment of Graphene Family Materials (GFMs) as a representative of 2D nanomaterials (NMs) to assess and predict 2D NMs health and environmental risks. The ACCORDs framework will operationalise safe and sustainable by design (SSbD) strategies proposed in past or ongoing H2020 projects or within OECD by correlating low-, medium-, and high-resolution physico-chemical-biological imagingbased methods with non-imaging methods in a tiered approach. ACCORDs will deliver the ACCORDs framework and user guidance, new imaging-based characterisation methods (3-6 methods), reference in vitro tests (up to three new tests), new reference 2D NMs (up to three) for different matrices, a new minimum information reporting guideline for FAIR data sharing and reuse of images as well as an atlas with reference images for diagnostics of compromised safety of GFMs / GFM products. The new guidelines and standard proposals will be submitted to standardisation bodies to allow creation of regulatory ready products. The novelty of ACCORDs is in translating the principles of medical imaging-based diagnostics to 2D material hazard diagnostics. ACCORDs will accelerate industrial sectors in the area of aviation, marine construction, drone production, flexible electronics, photovoltaics, photocatalytics and print inks-based sensors. The value ACCORDs proposes to the graphene industry are practical, easy, imaging-based tools for GFM quality monitoring next to the production line with a possibility to be correlated with advanced high-resolution imaging characterization methods in case hazard i.e. deviation from controls (benchmark values) are diagnosed. The ACCORDs framework and tools will contribute to the European Green Deal by addressing the topic: “Graphene: Europe in the lead” and to a new European strategy on standardization, released on 2nd February, 2022.

ACCORDs将开发一个基于成像的表征框架（ACCORDs框架），用于石墨烯家族材料（GFM）作为2D纳米材料（NM）的代表的整体相关评估，以评估和预测2D NM的健康和环境风险。ACCORDs框架将通过分层方法将低、中、高分辨率物理-化学-生物成像方法与非成像方法相关联，实施过去或正在进行的H2020项目或经合组织内部提出的安全和可持续设计（SSbD）战略。ACCORD将提供ACCORD框架和用户指南、新的基于成像的表征方法（3-6种方法）、参考体外试验（最多3种新试验）、不同基质的新参考2D NM（最多3种）、FAIR数据共享和图像重复使用的新最低信息报告指南以及用于诊断GFM/ GFM产品安全性受损的参考图像图集。新的指南和标准提案将提交给标准化机构，以允许创建监管就绪的产品。ACCORD的新奇在于将基于医学成像的诊断原理转化为2D材料危害诊断。ACCORD将加速航空、海洋建筑、无人机生产、柔性电子、光化学、光催化和印刷油墨传感器领域的工业部门。ACCORD为石墨烯行业提供的价值是实用、简单、基于成像的工具，用于生产线附近的GFM质量监测，在诊断出危险即与控制（基准值）偏差的情况下，可以与先进的高分辨率成像表征方法相关联。ACCORDs框架和工具将通过解决主题“石墨烯：欧洲领先”和2022年2月2日发布的新欧洲标准化战略，为欧洲绿色协议做出贡献。