University of North Carolina - Chlamydia Vaccine Initiative (UNC-CVI)

为了推进针对主要性传播疾病的疫苗的开发，NIAID宣布 U19性传播感染合作研究中心(STI CRC)计划。作为回应， 北卡罗来纳大学衣原体疫苗倡议(UNC-CVI)汇集了一批经验丰富的 衣原体研究人员、性传播感染临床医生和疫苗开发专家解决 预防衣原体感染往往具有破坏性的健康和生殖后果的疫苗 女人。UNC-CVI将是一个大型的多方面组织，包括核心、项目和 多个国家和国际站点的合作者。建立和维护基础设施以 确保企业平稳、高效地运行将是行政核心的责任 A.由皮托尼·达维尔医学中心和皮凯瑟琳·奥康奈尔博士项目领导，并得到以下资源的支持： 北卡罗来纳大学教堂山分校，该国领先的研究型大学之一。核心A领导层将结合科学 具有行政经验的专门知识，以确保成功完成以下具体目标：1 -行政监督，确保北卡罗来纳大学-CVI科学家和工作人员协同工作，完成 中心研究方案的短期和长期目标，包括财务、资源管理 和生物武器；2-通信监督-为不同的组件提供管道 中心和NIH共享数据和结果，排除障碍，并将信息传播给 科学界和公众；3--科学监督--监测里程碑和交付成果 监督冲突解决、试剂和数据共享以及知识产权问题；4-发展 监督、制定和管理发展研究计划，以支持研究和 下一代STI疫苗研究人员的职业生涯；5-生物统计学支持小组，确保中心 项目和DRP获奖者可以获得有效的基础、 翻译和临床研究。

To advance the development of vaccines against major sexually-transmitted diseases, NIAID announced the the U19 Sexually Transmitted Infections Cooperative Research Center (STI CRC) program. In response, the University of North Carolina Chlamydia Vaccine Initiative (UNC-CVI) has assembled a group of seasoned Chlamydia researchers, STI clinicians and vaccine development experts to address the development of a vaccine to prevent the often-devastating health and reproductive consequences of Chlamydia infection in women. UNC-CVI will be a large and multifaceted organization, encompassing cores, projects and collaborators at multiple national and international sites. Establishing and maintaining the infrastructure to ensure the smooth and efficient running of this enterprise will be the responsibility of the Administrative Core A. Headed by Center PI Toni Darville MD and project PI Catherine O’Connell PhD, and backed by resources at UNC Chapel Hill, one of the country’s leading research universities. Core A leadership will combine scientific expertise with administrative experience to ensure the successful completion of the following specific aims: 1 – Administrative oversight, ensure that UNC-CVI scientists and staff work synergistically to accomplish the short- and long-term goals of the Center’s research program, including management of finances, resources and biospecimens; 2 – Communications oversight – provide a conduit for the disparate components of the Center and NIH to share data and results, troubleshoot roadblocks, and disseminate information to the scientific community and the public; 3 – Scientific oversight – monitoring milestones and deliverables, and overseeing conflict resolution, reagent- and data sharing and intellectual property issues; 4 – Developmental oversight, developing and administering the Development Research Program, to support the research and careers of the next generation of STI vaccine researchers; 5 – Biostatistical support group, ensuring the Center projects and DRP awardees have access to the cutting-edge statistical expertise essential for effective basic, translational and clinical research.