Multidisciplinary Training in Substance Abuse Research

项目摘要 这是迈阿密大学米勒医学院T32培训补助金的重新提交，旨在 培训药物滥用研究方面的博士前和博士后学员。我们计划的目标是训练 科学家和临床医生，以更好地了解基本的科学概念的物质滥用， 将“在实验室”的发现转化为“床边”的临床实践。述报知 处方阿片类药物滥用的增加，必须了解药物的潜在机制 在多学科层面上，改善循证治疗，并为患者制定有效的治疗方法 患有成瘾性疾病。我们的总体目标是为学员提供专业技能， 药物滥用研究的学术生涯。该计划的主要目标包括：1）为学员提供 无论是严格的实验室研究经验，还是以患者或人群为导向的研究经验， 药物滥用研究，通过将有前途的候选人与优秀的导师联系起来， 根据科学资格和药物滥用培训经验进行挑选; 2）为学员提供 基本的研究技能和有关药物滥用研究职业发展的信息， 结构化的课程作业、讲座和研讨会，强调道德操守和科学诚信方面的培训 学术“生存技能”，具体的研究工具和接触不同的研究方法; 3） 通过与高级教师积极共同指导学员，提高和教授初级教师的指导技能 有正式培训计划的教师。该计划将包括杰出的导师，除了 在他们的重点研究领域的成功，致力于教学广泛的研究技能，如 进行文献的学术评论;制定假设和研究设计;开发必要的 统计技能，口头和书面介绍科学发现和赠款写作;理解问题， 界定科学诚信和道德的潜在问题。项目领导层将进一步确保 监督学员的进步。我们经验丰富的导师团队，拥有积极的外部同行评审资金 致力于最高质量的研究经验，提供药物滥用方面的最先进的培训 research.拟议的方案纳入了一个全面的培训计划，负责进行 通过招聘和留住女性和少数族裔候选人来研究和促进多样性。大学 迈阿密为这一培训机制提供了一个充满活力、激励人心和学院式的学习环境。

Project Summary This is a resubmission of a T32 training grant from the University of Miami, Miller school of Medicine aimed at training pre- and post-doctoral trainees in drug abuse research. Our program's goal is to train both basic scientists and clinicians to better understand the basic science concepts underlying substance abuse and to translate the findings made “at the bench” to inform clinical practices at the “bedside”. With the alarming increase in the abuse of prescription opioids it is imperative to understand the mechanisms underlying drug abuse at a multidisciplinary level to improve evidence-based and formulate effective treatments for patients with addictive disorders. Our overall goal is to provide trainees with professional skills to pursue productive academic careers in drug abuse research. Primary objectives of this program include: 1) provide trainees with either a rigorous laboratory research experience or patient- or population-oriented research experience in substance abuse research by linking promising candidates with outstanding mentors who are meticulously selected based on scientific qualifications and experience in drug abuse training; 2) to provide trainees with essential research skills and information regarding career development in substance abuse research through structured course work, lectures and seminars, which emphasizes training in ethics and scientific integrity academic "survival skills," specific research tools and exposure to diverse research methodologies; 3) to enhance and teach skills in mentorship to junior faculty through active co-mentoring of trainees with senior faculty with a formal training program. This program will include outstanding mentors who, in addition to success in their focused areas of research, are committed to teaching broad research skills, such as performing scholarly reviews of the literature; formulating hypotheses and study design; developing essential skills in statistics, oral and written presentation of scientific findings and grant writing; understanding issues and defining potential problems of scientific integrity and ethics. The program leadership will further ensure close monitoring of trainee progress. Our team of experienced mentors with active, external peer-reviewed funding are committed to the highest quality research experience, providing state of art training in substance abuse research. The proposed program incorporates a comprehensive training plan in the responsible conduct of research and promotes diversity by recruiting and retaining women, and minority candidates. The University of Miami offers a dynamic, stimulating and collegial learning environment for this training mechanism.