Administrative Core

摘要 行政核心(行政核心)将建立为一个综合的、确定优先事项的联合体 涉及首席调查员(PI/PD)、CETR内部领导小组和一名科学顾问 委员会(SAC)与NIAID的项目参与，以提高潜在的产品成果。这个 管理职能旨在提供行政支持，促进个人的成功 项目，促进有效整合和分配支助职能和资源，并刺激 CETR成员之间的科学交流，从而确保整个CETR方案实现其 目标。管理核心将由PI中心大卫·佩林博士监督，他将由一名 经验丰富的行政主管和财务总监，负责协调和管理所有行政职能。做到最好 为了推进CETR目标，行政核心将协调项目负责人和他们的 合作者(和分包商)、科学/发现核心主管和SAC成员。这些会议是 旨在通过发现矩阵推进化合物，从而实现及时和客观的“去，不去” 做决定。管理核心还将促进与SAC的年度审查会议，并反向站点 访问NIAID。它将编制并向NIH提交年度进展报告，并将协调研究 出版物、会议介绍、报告和新闻稿。最后，它将是与专利的联系 《经济、社会和文化权利国际公约》产生的知识产权保护和许可小组，以及许可 机遇。管理核心将执行以下具体目标：1)建立高效的 为项目负责人和核心主管提供必要的监督和指导的管理结构； 有效地将科学咨询委员会作为战略顾问整合到发现/发展中 过程，促进科学交流；2)最大限度地配置资源，优先安排化合物 通过以下方式建立关键指标来进行发展：进行、不进行决策和资源分配 支持项目负责人和核心总监的密切互动，并安排定期评审；3)开发 评估年终项目绩效、准备中期和年终报告以及招聘 酌情作为补充项目；4)协调出版物、成果介绍和新闻稿 从这些研究的结果中产生；以及5)建立内部组织结构，以处理 材料转让协议、保密性、知识产权申请和许可机会的后勤 并为解决冲突和其他业务问题制定管理计划。

Abstract The Administrative Core (Admin Core) will be established as an integrated, priority-setting consortium involving the Principal Investigator (PI/PD), an internal CETR leadership team, and a Scientific Advisory Committee (SAC) with programmatic involvement from NIAID to enhance potential product outcome. The management function is designed to provide administrative support that facilitates the success of individual Projects, promotes effective integration and allocation of support functions and resources, and stimulates scientific exchange between CETR members, thus ensuring that the overall CETR program achieves its objectives. The Admin Core will be overseen by the Center PI, Dr. David Perlin, who will be supported by a seasoned administrator and financial director to coordinate and manage all administrative functions. To best advance CETR objectives, the Admin Core will coordinate regular meetings of Project Leaders and their collaborators (and subcontractors), scientific/discovery Core Directors, and SAC members. The meetings are designed to advance compounds through the discovery matrix enabling timely and objective “go, no-go” decision making. The Admin Core will also facilitate an annual review meeting with the SAC, and reverse site visit at NIAID. It will produce and submit the annual progress report to the NIH, and it will coordinate research publications, meeting presentations, reports and press releases. Finally, it will be the liaison with the Patent and Licensing group for the protection of intellectual property generated by the CETR, as well as licensing opportunities. The Admin Core will execute the following Specific Aims: 1) establish a highly efficient management structure that provides essential oversight and guidance for Project Leaders and Core Directors, effectively integrates the Scientific Advisory Committee as strategic advisors in the discovery/development process, and promotes scientific exchange; 2) maximize allocation of resources and prioritize compound development by establishing critical metrics for “go, no-go” decision making and resource allocations by supporting close interactions of Project Leaders and Core Directors and scheduling regular reviews; 3) develop an effective strategy to assess year-end Project performance, prepare interim and year-end reports, and recruit a Supplemental project, as appropriate; 4) coordinate publications, presentations of results, and press releases arising from the output of these studies; and 5) establish an internal organizational structure that addresses logistics for material transfer agreements, confidentiality, intellectual property filings and licensing opportunities and negotiations; and develop a managerial plan for conflict resolution and other operational issues.