Improving cardiac rehabilitation outcomes using data from daily life: A novel, multi-method ambulatory assessment approach

利用日常生活数据改善心脏康复结果：一种新颖的多方法动态评估方法

• 批准号: 10399972
• 负责人: Deanna Kaplan
• 金额: $ 2.73万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-21 至 2022-03-04
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10399972
• 关键词: Accelerometer; Activities of Daily Living; Address; Adherence; Affect; Behavior; Behavioral Medicine; Biological; Biological Markers; Cardiac rehabilitation; Cardiology; Cardiovascular Diseases; Cardiovascular system; Cause of Death; Cognitive; Collection; Data; Distress; Dropout; Ecological momentary assessment; Emotions; Enrollment; Environment; Epidemiology; Event; Exercise Tolerance; Foundations; Gender; Goals; Home; Intervention; Investigation; Life; Medical; Mentors; Methodology; Methods; Modeling; Moods; Movement; Outcome; Participant; Patient Self-Report; Patient-Focused Outcomes; Patients; Pattern; Periodicity; Procedures; Process; Psychosocial Factor; Recommendation; Rehabilitation Outcome; Research; Research Methodology; Research Personnel; Resolution; Rest; Social Interaction; Social support; Symptoms; Technology; Testing; Time; Training; Translating; Traumatic injury; Treatment outcome; United States; Withdrawal; Woman; adaptive intervention; behavior measurement; behavior observation; cognitive reappraisal; compliance behavior; distraction; emotion regulation; experience; health related quality of life; heart rate monitor; improved; innovation; men; novel; patient response; person centered; precision medicine; predictive marker; prevent; programs; psychologic; psychological distress; psychosocial; responders and non-responders; response; treatment adherence; treatment response

PROJECT SUMMARY / ABSTRACT Cardiac rehabilitation (CR) is widely recognized as an effective and life-prolonging treatment for cardiovascular disease (CVD), yet many patients do not benefit from treatment. More than half of patients who begin, ultimately dropout. Even among treatment adherent patients, one third are “non-responders”, and past investigations into the demographic and biological profiles of responders and non-responders have been unable to identify reliable differences that can explain why. Prior research on treatment adherence and responsiveness in CR has been limited by reliance on methodological approaches that only allow for a small number of assessments taken in medical environments that have limited generalizability to actual experiences during normal daily life. Building on the large body of research indicating that cardiovascular events and psychosocial distress share a common epidemiology, and by emerging evidence that transdiagnostic psychosocial processes (e.g., emotion regulation, daily behaviors and social interactions) are predictive of key cardiovascular outcomes, the present study employs a novel assessment approach to collect data from patients enrolled in CR as they go about their normal daily lives. N = 50 patients who are enrolling in a typical 12-week cardiac rehabilitation program will undergo two weeks of daily life assessments (the first during week 1 and the second during week 12 of the program). Assessments will include: 1) Ecological Momentary Assessment (EMA) for the collection of subjective data about patients’ cognitive and emotion regulation strategies in daily life, 2) behavioral observation using the Electronically Activated Recorder (EAR) for passive assessment of patients’ daily behaviors and social interactions, and 3) an Actiwatch, for passive assessment of accelerometry, heartrate and heartrate variability during daily life. Participant burden is minimal due to the use of passive assessment approaches. We will use advanced longitudinal, person-centered modeling approaches to identify specific, treatment-modifiable factors that affect treatment adherence and response to CR. We hypothesize that cognitive and emotion regulation strategies (Aim 1), daily activity pacing and social interactions (Aim 2), and patterns in continuously assessed cardiovascular biomarkers (Aim 3, Exploratory) will each predict treatment adherence and responsiveness outcomes. The study is innovative in that it is the first study to integrate these three cutting-edge methods, and is among the very first to apply “high resolution” daily life research approaches to improving treatment outcomes for patients with CVD. Results will be used as pilot data to inform a K or R application focused on developing and testing a precision-medicine informed intervention that further leverages ambulatory technologies such as mobile adaptive interventions to increase patient responsiveness to CR through daily life treatment targets identified through the present study.

项目摘要/摘要

项目成果

Biological and psychological predictors of heart rate patterns during physical activity.

身体活动期间心率模式的生物和心理预测因素。

• DOI: 10.1016/j.psychsport.2022.102346
• 发表时间: 2023
• 期刊: Psychology of sport and exercise
• 影响因子: 3.4
• 作者: Kaplan,DeannaM;Palitsky,Roman;Dunsiger,ShiraI;Wu,Wen-Chih;Parker,AmiraG;Troubh,JessicaK;Whitworth,JamesW;Bock,BethC
• 通讯作者: Bock,BethC