Non-invasive structural tissue analysis for low-cost, highly accurate, safe and rapid cancer diagnosis.
非侵入性结构组织分析可实现低成本、高精度、安全且快速的癌症诊断。
基本信息
- 批准号:10063925
- 负责人:
- 金额:$ 49.11万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Collaborative R&D
- 财政年份:2023
- 资助国家:英国
- 起止时间:2023 至 无数据
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
~50% of the global population will develop cancer in their lifetime \[WHO,2022\]. Breast cancer is the most common form, with 685,000 deaths/year globally \[WHO,2021\]. The economic cost of cancer is significant with the last estimate of the global economic cost at ~1.5% of Global GDP(£735bn). In the UK, the economic cost of cancer was estimated at £7.6bn/year in 2020 and is expected to rise with the ageing population \[PharmaTimes,2020\]. Early diagnosis of cancer is key to improving chances of survival. Furthermore, monitoring the efficacy of treatment is vital to health outcomes, as well as identifying/demonstrating/measuring treatment efficacy.As the global population rises, the number of cancer cases is expected to increase, driving the need for improved diagnostics. Current-state-of-the-art cancer diagnostics are limited to either invasive techniques that have limited specificity and selectivity or non-invasive techniques that are highly expensive. Both invasive and non-invasive techniques require a hospital appointment, limiting the uptake of screening programs. Hence, there is a rapidly growing need for improved cancer diagnostics.EosDx in collaboration with Keele University is looking to develop and optimise 'NISTA', a non-invasive structural tissue analysis device offering safe and accurate cancer diagnosis and monitoring. The consortium possesses leading expertise in x-ray diffraction, structural crystallography and tissue analysis and has previously developed game-changing technologies within the diagnostic sector.In this project, the consortium will focus on optimising the NISTA diagnostic device, enabling cancer diagnosis through X-ray diffraction imaging. The NISTA diagnostic improves significantly over current-state-of-the-art as it enables pre-symptomatic, rapid, safe, non-invasive and highly accurate cancer diagnostics.This highly innovative project aims to expand the diagnostics sector from within the UK, driving the growth of a completely new industry sub-segment
全球约50%的人口将在其一生中患上癌症[WHO,2022]。乳腺癌是最常见的形式,全球每年有685,000人死亡[WHO,2021]。癌症的经济成本很高,最新估计全球经济成本约占全球GDP的1.5%(7350亿英镑)。在英国,2020年癌症的经济成本估计为76亿英镑/年,预计将随着人口老龄化而上升[PharmaTimes,2020]。癌症的早期诊断是提高生存机会的关键。此外,监测治疗效果对健康结果至关重要,也是确定/展示/衡量治疗效果的关键。随着全球人口的增加,预计癌症病例数量将增加,这推动了对改进诊断的需求。目前最先进的癌症诊断限于具有有限特异性和选择性的侵入性技术或非常昂贵的非侵入性技术。侵入性和非侵入性技术都需要医院预约,限制了筛查计划的采用。因此,对改进癌症诊断的需求迅速增长。EosDx与基尔大学合作,正在寻求开发和优化“NISTA”,这是一种非侵入性结构组织分析设备,可提供安全准确的癌症诊断和监测。该联盟在X射线衍射、结构晶体学和组织分析方面拥有领先的专业知识,此前曾在诊断领域开发过改变游戏规则的技术。在该项目中,该联盟将专注于优化NISTA诊断设备,通过X射线衍射成像实现癌症诊断。NISTA诊断技术比目前最先进的诊断技术有了显著的改进,因为它可以实现症状前、快速、安全、非侵入性和高度准确的癌症诊断。这个高度创新的项目旨在从英国国内扩展诊断领域,推动一个全新的行业细分市场的发展。
项目成果
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其他文献
Internet-administered, low-intensity cognitive behavioral therapy for parents of children treated for cancer: A feasibility trial (ENGAGE).
针对癌症儿童父母的互联网管理、低强度认知行为疗法:可行性试验 (ENGAGE)。
- DOI:
10.1002/cam4.5377 - 发表时间:
2023-03 - 期刊:
- 影响因子:4
- 作者:
- 通讯作者:
Differences in child and adolescent exposure to unhealthy food and beverage advertising on television in a self-regulatory environment.
在自我监管的环境中,儿童和青少年在电视上接触不健康食品和饮料广告的情况存在差异。
- DOI:
10.1186/s12889-023-15027-w - 发表时间:
2023-03-23 - 期刊:
- 影响因子:4.5
- 作者:
- 通讯作者:
The association between rheumatoid arthritis and reduced estimated cardiorespiratory fitness is mediated by physical symptoms and negative emotions: a cross-sectional study.
类风湿性关节炎与估计心肺健康降低之间的关联是由身体症状和负面情绪介导的:一项横断面研究。
- DOI:
10.1007/s10067-023-06584-x - 发表时间:
2023-07 - 期刊:
- 影响因子:3.4
- 作者:
- 通讯作者:
ElasticBLAST: accelerating sequence search via cloud computing.
ElasticBLAST:通过云计算加速序列搜索。
- DOI:
10.1186/s12859-023-05245-9 - 发表时间:
2023-03-26 - 期刊:
- 影响因子:3
- 作者:
- 通讯作者:
Amplified EQCM-D detection of extracellular vesicles using 2D gold nanostructured arrays fabricated by block copolymer self-assembly.
使用通过嵌段共聚物自组装制造的 2D 金纳米结构阵列放大 EQCM-D 检测细胞外囊泡。
- DOI:
10.1039/d2nh00424k - 发表时间:
2023-03-27 - 期刊:
- 影响因子:9.7
- 作者:
- 通讯作者:
的其他文献
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{{ truncateString('', 18)}}的其他基金
An implantable biosensor microsystem for real-time measurement of circulating biomarkers
用于实时测量循环生物标志物的植入式生物传感器微系统
- 批准号:
2901954 - 财政年份:2028
- 资助金额:
$ 49.11万 - 项目类别:
Studentship
Exploiting the polysaccharide breakdown capacity of the human gut microbiome to develop environmentally sustainable dishwashing solutions
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2896097 - 财政年份:2027
- 资助金额:
$ 49.11万 - 项目类别:
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A Robot that Swims Through Granular Materials
可以在颗粒材料中游动的机器人
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2780268 - 财政年份:2027
- 资助金额:
$ 49.11万 - 项目类别:
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Likelihood and impact of severe space weather events on the resilience of nuclear power and safeguards monitoring.
严重空间天气事件对核电和保障监督的恢复力的可能性和影响。
- 批准号:
2908918 - 财政年份:2027
- 资助金额:
$ 49.11万 - 项目类别:
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Proton, alpha and gamma irradiation assisted stress corrosion cracking: understanding the fuel-stainless steel interface
质子、α 和 γ 辐照辅助应力腐蚀开裂:了解燃料-不锈钢界面
- 批准号:
2908693 - 财政年份:2027
- 资助金额:
$ 49.11万 - 项目类别:
Studentship
Field Assisted Sintering of Nuclear Fuel Simulants
核燃料模拟物的现场辅助烧结
- 批准号:
2908917 - 财政年份:2027
- 资助金额:
$ 49.11万 - 项目类别:
Studentship
Assessment of new fatigue capable titanium alloys for aerospace applications
评估用于航空航天应用的新型抗疲劳钛合金
- 批准号:
2879438 - 财政年份:2027
- 资助金额:
$ 49.11万 - 项目类别:
Studentship
Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
- 批准号:
2890513 - 财政年份:2027
- 资助金额:
$ 49.11万 - 项目类别:
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CDT year 1 so TBC in Oct 2024
CDT 第 1 年,预计 2024 年 10 月
- 批准号:
2879865 - 财政年份:2027
- 资助金额:
$ 49.11万 - 项目类别:
Studentship
Understanding the interplay between the gut microbiome, behavior and urbanisation in wild birds
了解野生鸟类肠道微生物组、行为和城市化之间的相互作用
- 批准号:
2876993 - 财政年份:2027
- 资助金额:
$ 49.11万 - 项目类别:
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