11th International Conference on Cryptococcus and Cryptococcosis (ICCC)

第十一届隐球菌和隐球菌病国际会议（ICCC）

• 批准号: 10399173
• 负责人: David R Boulware
• 金额: $ 1.7万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-02-01 至 2023-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10399173
• 关键词: Acquired Immunodeficiency Syndrome; Adult; Affect; Africa; Africa South of the Sahara; African; Antifungal Agents; Antifungal Therapy; Archives; Area; Basic Science; Botswana; COVID-19 pandemic; Caring; Central Nervous System Infections; Cessation of life; Characteristics; Clinical; Clinical Investigator; Clinical Sciences; Clinical Trials; Collaborations; Communicable Diseases; Communities; Country; Cryptococcal Meningitis; Cryptococcosis; Cryptococcus; Cryptococcus neoformans; Disease; Etiology; Face; Failure; Family; Floor; Fostering; Funding; Future; Genome; Goals; Grant; HIV; HIV antiretroviral; Immune system; Immunity; Immunocompetent; Immunocompromised Host; Immunosuppression; Incidence; Income; International; International Aspects; Invaded; Knowledge; Medical; Meningitis; Microbiology; Minority; Molecular; Morbidity - disease rate; Mycoses; Opportunistic Infections; Oral; Participant; Pathogenesis; Pathogenicity; Patients; Persons; Postdoctoral Fellow; Predisposition; Prevention strategy; Program Development; Property; Request for Proposals; Research; Research Personnel; Resources; Retroviridae Infections; Risk; Scientific Advances and Accomplishments; Scientist; Sexual Reproduction; Signal Transduction; Site; South Africa; Structure; Students; The science of Mycology; Time; Translational Research; Travel; Twitter; Uganda; Underrepresented Minority; United States National Institutes of Health; Virulence; Wheelchairs; Woman; antiretroviral therapy; career; clinical practice; digital; fungus; graduate student; innovation; meetings; mortality; neglect; novel; pandemic disease; parity; pathogen; post-COVID-19; posters; preclinical development; programs; screening; social media; symposium; therapy development; tool; treatment strategy; vaccine development; web site; working group

ABSTRACT This proposal requests partial support for the 11th International Conference on Cryptococcus and Cryptococcosis (ICCC) to be held in Kampala, Uganda, January 10-14, 2022. Cryptococcosis accounts for 15% of AIDS-related deaths globally. Cryptococcal meningitis remains the most common neuroinfection among all adults in Sub-Saharan Africa and continues to be a major threat to a growing number of non-HIV immunocompromised persons. The broad and long-term goal of this ICCC is to bring together the world's leading researchers in this expanding field to foster cross-disciplinary discussions, research, and clinical collaborations to enhance our understanding of the mechanisms of Cryptococcus pathogenicity and best management of cryptococcosis. The specific aims of this meeting will be to convene leading experts whose expertise covers critical areas within this field, as well as early career and junior investigators, students, and postdocs. We anticipate hosting 300 participants. The program will be structured into 17 sessions covering the diverse properties and characteristics of the pathogen as well as host susceptibility and immunity, emphasizing what makes a normal host suddenly susceptible to this disease. Importantly, the conference will provide ample coverage of current and novel antifungals – ranging from pre-clinical development programs through ongoing/future clinical trials. Abstracts from junior investigators, graduate students, and postdoctoral fellows will be included among those selected for oral presentation. The conference will host two poster sessions which will permit all participants to actively contribute to these topics. Of the 17 session blocks, 12 blocks will be concurrent sessions to allow for smaller working groups to meet and more students / trainees to present their abstracts. The R13 resources will go towards supporting travel grant participation by graduate students and specifically under-represented minority scholars from US and Africa who present abstracts. We will seek parity with respect to women and minorities in the selection of speakers and organizing committee, starting with 2 of the 3 ICCC co-chairs being a woman or a minority. We will target at least ~40% of plenary speakers to be women and ~10% under-represented minorities. Childcare will be provided. The 11th ICCC is significant because focuses on an important infectious disease afflicting both immunocompromised and immunocompetent people. This is the only such conference that brings together basic scientists and clinical investigators who investigate cryptococcosis. This is the first time the conference will be held in Africa with objectives: 1) to build new US-African translational research collaborations; 2) to define the important clinical, translational, and basic science research agenda to forge new avenues for novel prevention and treatment strategies.

摘要 该提案要求部分支持第十一届国际隐球菌大会和 隐球菌病(ICCC)将于2022年1月10日至14日在乌干达坎帕拉举行。隐球菌病占了 占全球艾滋病相关死亡人数的15%。隐球菌性脑膜炎仍然是最常见的神经感染 在撒哈拉以南非洲的所有成年人中，并继续成为越来越多的非艾滋病毒感染者的主要威胁 免疫功能受损的人。 ICCC的广泛和长期目标是将世界领先的研究人员聚集在一起 扩展领域以促进跨学科讨论、研究和临床协作，以增强我们的 了解隐球菌病的致病机制及对隐球菌病的最佳治疗。 本次会议的具体目标是召集专业知识涵盖关键领域的主要专家。 该领域的研究领域，以及早期职业和初级调查人员、学生和博士后。我们 预计将接待300名参与者。该计划将分为17个课程，涵盖不同的 病原菌的性质和特征以及寄主的敏感性和免疫力，强调 是什么让一个正常的宿主突然容易感染这种疾病。重要的是，这次会议将提供 对当前和新型抗真菌药物的广泛报道-从临床前开发计划到 正在进行的/未来的临床试验。初级研究员、研究生和博士后研究员的摘要 将包括在被选中进行口头陈述的人中。会议将举办两个海报会议 这将使所有与会者都能为这些主题作出积极贡献。在17个会话块中，有12个块 将同时举行会议，以便较小的工作组开会，并允许更多的学员/实习生 展示他们的摘要。R13资源将用于支持毕业生参加旅行补助金 学生，特别是来自美国和非洲的代表不足的少数民族学者，他们提交了摘要。 我们将在挑选发言者和组织工作时争取妇女和少数群体的平等。 委员会的成员，从ICCC的3名联席主席中的2名女性或少数族裔开始。我们的目标至少是 全体会议发言人中约40%为女性，约10%为代表不足的少数群体。将提供托儿服务。 第11届ICCC具有重要意义，因为它关注的是一种折磨两人的重要传染病 免疫功能低下和免疫能力正常的人。这是唯一一次这样的会议 研究隐球菌病的基础科学家和临床研究人员。这是世界上第一次 会议将在非洲举行，目标是：1)建立新的美非翻译研究 协作；2)确定要制定的重要临床、翻译和基础科学研究议程 为新的预防和治疗战略开辟新途径。