Justice Community Opioid Innovation Network (JCOIN): TCU Clinical Research Center

正义社区阿片类药物创新网络 (JCOIN)：TCU 临床研究中心

• 批准号: 10399485
• 负责人: DANICA K KNIGHT
• 金额: $ 194.4万
• 依托单位: TEXAS CHRISTIAN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-15 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10399485
• 关键词: Address; Adult; Adverse event; Appointment; Attitude; Client; Clinical; Clinical Research; Cluster randomized trial; Collaborations; Communities; Community Health; Community Health Networks; Continuity of Patient Care; Criminal Justice; Development; Effectiveness; Evidence based practice; Exploration Preparation Implementation and Sustainment; Face; Geography; Goals; Health; Health Services; Hybrids; Illinois; Individual; Intervention; Justice; Measures; Medical; Methodology; Mission; Modeling; National Institute of Drug Abuse; New Mexico; Opioid; Outcome; Patient Self-Report; Population; Public Health; Recording of previous events; Records; Research; Research Design; Research Personnel; Resources; Risk; Safety; Services; Site; Substance Use Disorder; System; Testing; Texas; Training; Translations; United States; Universities; advanced analytics; base; behavioral health; cost; data sharing; design; experience; illicit drug use; illicit opioid; implementation barriers; implementation framework; implementation intervention; implementation strategy; improved; improved outcome; innovation; medication-assisted treatment; member; opioid epidemic; opioid misuse; opioid use; opioid use disorder; opioid user; overdose death; performance site; rearrest; recruit; safety outcomes; service gap; substance use; treatment planning; uptake

Project Summary/Abstract Recognizing the current opioid crisis among justice-involved individuals and the need to intervene at the intersection of justice and community health, the current study proposes to explore positive outcomes associated with a multi-level hybrid implementation approach. The strategy capitalizes on facilitated collaboration (coaching), training, and cross-system data sharing in an effort to leverage improvements in criminal justice and community behavioral health (CBH) interagency collaboration. The ultimate goal of the proposed project is to improve local community public health and safety outcomes for reentering justice- involved individuals who have a history of (or are at risk for) using opioids. Our specific aims are to 1) increase access to and retention in appropriate CBH and medical (MAT) services for reentering justice-involved individuals who have a history of or are at risk for opioid use, 2) improve outcomes (including costs) associated with public health and safety; 3) compare two implementation approaches on systems-level outcomes designed to increase service initiation and receipt with respect to implementation and service outcomes; and 4) examine the impact of these two approaches on justice-involved individual outcomes. The proposed study examines both Implementation and Implementation-Effectiveness, seeking to answer the questions of which implementation strategy (bottom up versus horizontal cascading) is most effective for rapid uptake of evidence- based practices within justice settings. The study also examines which implementation strategy is most effective for increasing service linkage and initiation, services retention, and improved opioid-related public health safety outcomes. A Hybrid Type 3 study design will be used and include a primary aim to compare two implementation strategies and two interventions at two levels (client and system), and a secondary aim to assess client-level outcomes associated with the trial. The study design will integrate 2 robust methodologies (stepped wedge and cluster randomized trial), and will include 18 clinical research performance sites (communities) located in Texas, New Mexico and Illinois. The proposed multi-site JCOIN CRC application includes a highly experienced team of Multiple PIs, investigators, and partners, and will contribute to the JCOIN network in an effort to establish a national consortium of investigators examining promising approaches designed to improve the capabilities and capacity of the justice system to more effectively address the opioid epidemic.

项目概要/摘要 认识到当前涉及正义的个人中存在阿片类药物危机以及需要进行干预 司法与社区健康的交叉点，当前的研究建议探索积极的成果 与多层次混合实施方法相关。该战略利用了便利 协作（辅导）、培训和跨系统数据共享，以努力利用改进 刑事司法和社区行为健康 (CBH) 机构间合作。该项目的最终目标是 拟议的项目是为了改善当地社区的公共卫生和安全成果，以重新进入司法管辖区- 涉及有使用阿片类药物史（或有使用阿片类药物风险）的个人。我们的具体目标是 1) 增加 获得并保留适当的 CBH 和医疗 (MAT) 服务，以便重新参与司法工作 有阿片类药物使用史或有使用阿片类药物风险的个人，2) 改善相关结果（包括成本） 与公共健康和安全有关； 3）比较两种实施方法的系统级结果 旨在增加实施和服务成果方面的服务启动和接收；和 4) 研究这两种方法对涉及正义的个人结果的影响。拟议的研究 检查实施和实施有效性，寻求回答以下问题： 实施策略（自下而上与水平级联）对于快速获取证据最有效 基于司法环境的实践。该研究还考察了哪种实施策略最有效 有效增加服务联系和启动、服务保留以及改善与阿片类药物相关的公众 健康安全结果。将使用混合型 3 研究设计，其主要目的是比较两种 实施策略和两个层面（客户和系统）的两项干预措施，以及次要目标 评估与试验相关的客户级结果。研究设计将整合两种稳健的方法 （阶梯式楔形和整群随机试验），并将包括 18 个临床研究表现点 （社区）位于德克萨斯州、新墨西哥州和伊利诺伊州。拟议的多站点 JCOIN CRC 应用 包括一支由多个 PI、研究人员和合作伙伴组成的经验丰富的团队，并将为 JCOIN 网络致力于建立一个全国性的研究人员联盟，研究有前景的方法 旨在提高司法系统的能力和能力，更有效地解决阿片类药物问题 流行性。