Xenbase - Computation

组件：计算 项目摘要/摘要 计算组件的目标是保持Xenbase的运行、可靠和响应能力， 维护和升级高峰所需的硬件、基础设施、软件和系统 并制定和支持其他各节所述的拟议改进措施 此应用程序的。像Xenbase这样的知识库必须集成和处理不同的 数据，并为用户提供查询和浏览其内容的工具和界面。这些都是 计算过程。此外，Xenbase必须与外部数据库和 资源(NCBI、AGR、出版商)，以同步内容并提供带注释的非洲爪哇 数据。尽管用户看不见，但会发生大量的计算 每次研究人员使用Xenbase时，都是在幕后。Xenbase是一种复杂的计算 由多个独立的数据库、许多不同的软件应用程序、 用户和馆长网络界面，以及许多自动化数据交换管道。为了确保 稳定性和增强性能，工具集隔离在各自的虚拟机(VM)上- 我们目前在私有云中运行大约20个虚拟机，并且我们不断地监视、测试、维护和修复 让一切顺利运行的虫子。每次实现新软件时，我们都会在独立的 VMS，然后对其进行优化并与现有系统集成。所有这些活动都包含在 计算组件，对于实现我们的总体项目目标至关重要。在这 组件，我们描述维护当前功能所需的计算工作，生成 实施扩展和改进所需的自定义内容和资源 下一个颁奖周期。 目标1.升级硬件、服务器和软件堆栈以增加容量并进行扩展 功能。 目的2.维护和扩展Xenbase含量的计算。 目标3.管理和监控网络和系统

Component: COMPUTATION PROJECT SUMMARY/ABSTRACT The goal of the Computation component is to keep Xenbase operational, reliable, and responsive, to maintain and upgrade the hardware, infrastructure, software and systems necessary for peak performance and to develop and support the proposed improvements described in other sections of this application. Knowledgebases like Xenbase must integrate and process a diverse array of data and provide users with tools and interfaces to query and explore its content. These are all computational processes. In addition, Xenbase must interface with external databases and resources (NCBI, the AGR, publishers) to synchronize content and to provide annotated Xenopus data. Although invisible to the user, there is a considerable amount of computing that occurs behind the scenes every time a researcher uses Xenbase. Xenbase is a complex computing environment consisting of multiple, separate databases, many different software applications, user and curator web interfaces, and many automated data exchange pipelines. To ensure stability and enhance performance, tool sets are isolated on their own virtual machines (VMs) - we currently run ~20 VMs in our private cloud - and we constantly monitor, test, maintain, and fix bugs to keep it all running smoothly. Each time new software is implemented, we test it on isolated VMs, then optimize and integrate it with existing systems. All of this activity is contained within the Computation component and is paramount to achieving our overall project goals. In this component, we describe the computing work needed to maintain current functionality, generate custom content and the resources necessary to implement expansions and improvements over the next award cycle. Aim 1. Upgrade hardware, servers and software stack to increase capacity and expanded functionalities. Aim 2. Maintain and expand computation of Xenbase content. Aim 3. Manage and monitor networking and systems