Developmental Core

项目总结 第三海岸CFAR核心B：发展核心(DC) 第三海岸艾滋病研究中心(TC CFAR)发展核心(DC)是 哪些成员建立了由NIH资助的新研究，以推进行政核心(AC)优先的科学研究 议程。DC服务为TC CFAR的每个总体目标提供支持和支持。DC提供了一系列种子 所有教师的资助机制(核心补贴奖)、艾滋病毒研究新手(试点奖)、我们的 科学核心(核心资源奖)和社区合作伙伴(社区协作和社区 迷你奖)。DC在行政补充(AS)竞争中取得了成功，并协助AC 其他机制。在头5年，通过多个发展中心机制和 连同NU和UC从机构支持提供的总额中的860,000美元。在不到5年的时间里，回报 在这些投资上一直表现强劲。三个总体目标中的每一个项目都得到了DC Awards的资助 和行政副刊；总体目标2和3是最近从AC领导的战略规划中产生的 这里提议的DC工作增加了DC资助的项目的预期增长，以解决总体问题 目标2和3。艾滋病毒研究的新参与者和向DC提交的跨学科报告有所增加。 社区合作奖与HRSA资助的社区合作伙伴组织建立了关系， 除了从制定行政补编提案的过程中吸取经验教训外，还使 响应结束艾滋病毒流行(EHE)倡议和成功启动新的EHE科学 工作组正在开始建立更多的研究-实践伙伴关系。强大的导师是另一个DC 这项有助于初级教师职业发展的服务正在芝加哥大学发展艾滋病毒研究， 并开始改善整个CFAR中URM教职员工的代表性。一种新的跨机构和跨机构的 NHLBI资助的纪律职业发展计划(第三海岸与艾滋病毒相关的心血管和睡眠 障碍K12职业发展计划)正在协同未来非艾滋病并存疾病的增长研究 以及我们教员的职业生涯。初级教员获得DC审查小组经验，核心现在还将 指导一位新的联合主任，并让初级教员获得独立的NIH资助领导经验 轮值联席董事。DC还将CFAR成员导航到增强提案和项目的资源 发展，包括在DC提交之前和之后的指导以及在NIH之前的模拟研究部分审查 意见书。此次续签的目的是：(1)向TC CFAR成员提供种子资金，强调及早 阶段调查员(ESI)和新接触艾滋病毒研究的现有教员，以进一步加强高优先级艾滋病毒 研究；(2)向现有和新的社区合作伙伴提供信息和资金，提供公共卫生、预防和 护理服务，包括那些对抗导致艾滋病毒流行的结构性不平等的服务；(3)促进职业发展 开发，并改进提案导航-为艾滋病毒研究的新参与者和我们的 科学优先事项。

PROJECT SUMMARY THIRD COAST CFAR CORE B: DEVELOPMENTAL CORE (DC) The Third Coast Center for AIDS Research (TC CFAR) Developmental Core (DC) serves as the foundation from which members build new NIH-funded research that advances the Administrative Core (AC)-prioritized scientific agenda. DC services enable and fuel each of the TC CFAR Overall aims. The DC provides a range of seed funding mechanisms for all faculty (Core Subsidy Awards), faculty new to HIV research (Pilot Awards), our scientific Cores (Core Resource Awards), and community partners (Community Collaborative and Community Mini-Awards). DC has enabled success in competitions for administrative supplements (AS) and assists AC with other mechanisms. In the first 5 years, more than $5.6 million was awarded via multiple DC mechanisms and AS, with >$860,000 of that total contributed by NU and UC from institutional support. In less than 5 years, returns on these investments have been strong. Projects on each of the 3 Overall aims have been funded by DC Awards and Administrative Supplements; Overall aims 2 and 3 emerged from AC-led strategic planning more recently than Overall aim 1. DC work proposed here adds to anticipated growth in DC-funded projects addressing Overall aims 2 and 3. New entrants to HIV research, and trans-disciplinary submissions to the DC, have increased. Community Collaborative Awards built relationships with HRSA-funded community partner organizations that, along with learning from processes for Administrative Supplement proposal development, enabled a strong response to the Ending the HIV Epidemic (EHE) Initiative and the successful launch of new EHE Scientific Working Group that is starting to seed more research-practice partnerships. Strong mentorship is another DC service that contributes to junior faculty career development, is growing HIV research at University of Chicago, and starting to improve representation of URM faculty across the CFAR. A new cross-institutional and cross- disciplinary NHLBI-funded career development program (Third Coast HIV-related Cardiovascular and Sleep Disorders K12 Career Development Program) is synergizing future growth of non-AIDS co-morbidities research as well as our faculty’s careers. Junior faculty gain DC review panel experience, and the Core will now also mentor a new co-director and give junior faculty achieving independent NIH funding leadership experience as a rotating co-director. The DC also navigates CFAR members to resources that enhance proposal and project development, including mentoring before and after DC submissions and mock study section reviews prior to NIH submissions. The aims of this renewal are: (1) to provide seed funding to TC CFAR members, emphasizing early stage investigators (ESI) and established faculty new to HIV research, to further enhance high priority HIV research; (2) to inform and fund current and new community partners providing public health, prevention, and care services, including those countering structural inequities driving the HIV epidemic; (3) to enhance career development, and improve navigation to proposal-enhancing expertise for new entrants to HIV research and our scientific priorities.