Building research capacity for cancer disparities research with community-clinic partnerships in rural African American impoverished counties

与非洲裔美国农村贫困县的社区诊所合作伙伴关系建设癌症差异研究的研究能力

• 批准号: 10407810
• 负责人: CANDACE S JOHNSON
• 金额: $ 20万
• 依托单位: ROSWELL PARK CANCER INSTITUTE CORP
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10407810
• 关键词: Address; Administrator; Advanced Malignant Neoplasm; Adverse effects; African American; Area; Arkansas; Cancer Burden; Cancer Center; Cancer Center Support Grant; Cancer Control; Cancer Control Research; Cancer Research Project; Characteristics; Clinic; Collaborations; Communities; Community Healthcare; Community Outreach; Comprehensive Cancer Center; Computerized Medical Record; County; Data; Discrimination; Division of Cancer Control and Population Sciences; Documentation; Economics; Evidence based intervention; Evidence based program; Funding; Goals; Health; Healthcare; Healthcare Systems; Incidence; Individual; Infrastructure; Institutes; Institution; Interview; Malignant Neoplasms; Medical; Methodology; NCI-Designated Cancer Center; Needs Assessment; Outcome; PF4 Gene; Participant; Poverty; Poverty Areas; Process; Research; Rural; Science; Services; Standardization; Strategic Planning; Surveys; United States; Universities; Ursidae Family; anticancer research; cancer health disparity; cancer prevention; care delivery; community clinic; community engaged research; community engagement; community organizations; evidence base; experience; healthcare community; high risk population; implementation strategy; innovation; medical information system; member; mortality; racial and ethnic disparities; racism; ranpirnase; rural African American; rural area; rural poverty; social; underserved community

Arkansas is one of the most rural and impoverished states in the U.S., with rural, African Americans (AA) bearing a disproportionate burden of cancer and related outcomes. Due to the fact that rural AA are more likely to live in persistent poverty and experience poverty's adverse effects, the mortality and incidence rates for the four major cancers and all cancers combined in Arkansan AA are among the highest in the nation. These disparities in cancer-relevant outcomes are further compounded by decades of discrimination and racism. Despite the state's obvious need to advance cancer prevention and control efforts, there are no NCI- designated cancer centers that serve the state, nor a strategic plan to address cancer disparities among communities in rural persistent poverty counties. Without a formal, systematic plan for cancer research engaging communities in this high-need area of Arkansas, cancer prevention and control efforts will continue to be stymied in communities who desperately need treatment now. Our goal through this P30 supplement is to form a cross-cancer center partnership that leverages the infrastructure of Roswell Park Comprehensive Cancer Center (Roswell Park) and the University of Arkansas for Medical Sciences Winthrop P. Rockefeller Cancer Institute (UAMS/WPRCI) to programmatically advance a cancer control agenda to reduce cancer disparities experienced by rural AA communities in the highest need areas of the U.S. This study will simultaneously 1) gather clinic-, community-, and participant-level data to inform a strategic plan for cancer prevention and control; and 2) build sufficient capacity within institutions currently serving Arkansas rural persistent poverty areas to implement a systematic program of cancer research. We will use mixed methodology to characterize cancer-related factors in rural AA communities, ascertain the current cancer research capacity of healthcare clinics that serve the target area, and determine assets and gaps within institutions who serve these communities to implement cancer research. We will collect standardized survey data from 240 AA residing in rural persistent poverty counties, electronic medical records (EMR) data from three clinics that serve all 12 rural poverty persistent counties, and qualitative data from 12 in-depth interviews with clinic leaders and administrators. To build the area's capacity for cancer research in the target area, we will construct a Community Advisory Board (CAB) consisting of healthcare clinic and community leaders. Through engaging the CAB in all aspects of the study, we will build relationships between healthcare, community, and academic stakeholders to conduct rigorous cancer prevention and control research. This collaboration will be developed from already long-standing relationships with the healthcare system and rural AA community within our team, in addition to Roswell Park's innovative partnership with WPRCI/UAMS. This study will provide the necessary evidence base and partnership capacity to develop organized efforts (that have not yet been implemented) for cancer prevention and control in a high-risk population.

阿肯色州是美国最贫穷的农村州之一，非洲裔美国人（AA） 承担着不成比例的癌症和相关后果的负担。由于农村AA更有可能 生活在持续贫困中并经历贫困的不利影响， 阿肯色州AA的四种主要癌症和所有癌症的总和都是全国最高的。这些 几十年的歧视和种族主义进一步加剧了癌症相关结果的差异。 尽管国家显然需要推进癌症预防和控制工作，但没有NCI- 指定的癌症中心，服务于国家，也没有一个战略计划，以解决癌症之间的差距 农村持续贫困县社区。如果没有一个正式的、系统的癌症研究计划 在阿肯色州这个高需求地区的社区参与，癌症预防和控制工作将继续， 在那些急需治疗的社区中受到阻碍。我们的目标是通过这个P30补充， 形成跨癌症中心合作伙伴关系，利用罗斯韦尔公园综合医院的基础设施， 癌症中心（罗斯威尔公园）和阿肯色州大学医学科学温斯洛普P.洛克菲勒 癌症研究所（UAMS/WPRCI）以计划方式推进癌症控制议程，以减少癌症 美国需求最高地区的农村AA社区经历的差异 这项研究将同时1）收集诊所，社区和参与者层面的数据，以告知战略 癌症预防和控制计划; 2）在目前提供服务的机构内建立足够的能力 对阿肯色州农村持续贫困地区实施系统的癌症研究计划。我们将使用 混合方法来描述农村AA社区的癌症相关因素，确定目前的 为目标区域服务的医疗保健诊所的癌症研究能力，并确定资产和差距 为这些社区提供服务的机构开展癌症研究。我们将收集标准化调查 数据来自240个居住在农村持续贫困县的AA，电子病历（EMR）数据来自 为所有12个农村贫困县服务的三个诊所，以及来自12个深度访谈的定性数据 与诊所领导和管理人员进行沟通。为了建立该地区在目标地区进行癌症研究的能力，我们 将建立一个由医疗诊所和社区领导人组成的社区咨询委员会（CAB）。 通过让CAB参与研究的各个方面，我们将在医疗保健、 社区和学术界的利益相关者进行严格的癌症预防和控制研究。这 合作将从与医疗保健系统和农村地区已经建立的长期关系中发展出来。 除了罗斯威尔公园与WPRCI/UAMS的创新合作伙伴关系外，我们团队中的AA社区。 这项研究将为开展有组织的努力提供必要的证据基础和伙伴关系能力 (that尚未实施），用于高危人群的癌症预防和控制。