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Structural and functional characterization of phosphoglycosyl transferases from human pathogens

Structural and functional characterization of phosphoglycosyl transferases from human pathogens
人类病原体磷酸糖基转移酶的结构和功能表征
批准号：
10413360
负责人：
Gregory J Dodge
金额：
$3.43万
依托单位：
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
项目状态：
已结题
起止时间：
2019-09-01 至 2022-02-28
来源：
https://reporter.nih.gov/project-details/10413360
关键词：
Active SitesAddressAnabolismAntibioticsBiochemicalBiologicalBiological AssayBiological ProcessCampylobacterCampylobacter jejuniCrystallizationDetergentsDevelopmentDiffusionEnvironmentEnzymesEscherichia coliExhibitsFamily memberFucoseGlycoconjugatesGlycoproteinsIn VitroIntegral Membrane ProteinLeftLibrariesLinkLipid BilayersLipidsLipopolysaccharidesMembraneMethodsMolecularNucleosidesOryctolagus cuniculusPhasePhospholipidsPhosphorylcholinePlayPolymersPolysaccharidesProteinsReportingSpecificityStaphylococcus aureusStructureStyrenesSubstrate InteractionSubstrate SpecificityTechniquesTransferaseUridine Diphosphate SugarsVirulenceX-Ray Crystallographybasecolanic acidcopolymerdesignenzyme substrate complexexperimental studyextracellularhuman pathogenimmunogenicityin vivoinhibitor/antagonistinorganic phosphateinsightlipooligosaccharideluminescencemacromoleculemaleic acidnanoparticlepathogenpathogenic bacteriapreventprotein data bankscreeningsugarvaporvector

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Structural and functional characterization of phosphoglycosyl transferases from human pathogens
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