Tissue Acquisition and Cellular/Molecular Analysis

项目摘要/摘要：组织采集和细胞/分子分析共享资源 (美国汽车制造商协会) 组织获取与细胞/分子分析共享资源(TACMASR)的目标是 为亚利桑那大学癌症中心(UACC)研究人员提供访问临床注释HIGH的途径 通过精心维护的生物存储库与先进的人类和 使用最先进的仪器和专家分析和解释结果的动物组织分析 训练有素的员工。普遍同意使TACMASR能够采购、管理、注释和分发组织， 同意患者的血液和尿液样本。UACC生物资源库由一个中央集合组成 这包括来自多个器官部位的手术标本和几个特殊的收藏品 几笔大笔赠款的结果。一个监督委员会优先考虑样本的使用。TACMASR提供了 以下服务：1)生物信息库服务，用于高质量的样本收集、储存、制备和 加工和咨询，2)组织学和免疫组织化学，3)细胞和分子 病理学，4)显微镜(明场、相位对比度和广场荧光)，以及5)关于 相关技术和数据分析。TACMASR还提供咨询和援助 关于实验设计、样品制备、探头选择和参考数据资源 分析。TACMASR为主要的国家生物库工作做出了贡献，包括国际 基因组联盟，通过提供被录入癌症基因组图谱和 肿瘤学表达计划。

Project Summary / Abstract: Tissue Acquisition and Cellular / Molecular Analysis Shared Resource (TACMASR) The goal of the Tissue Acquisition and Cellular / Molecular Analysis Shared Resource (TACMASR) is to provide University of Arizona Cancer Center (UACC) investigators with access to clinically annotated high quality human specimens through a meticulously maintained biorepository coupled with advanced human and animal tissue analysis using state-of-the art instrumentation and expert analysis and interpretation of results by well trained staff. A universal consent enables TACMASR to procure, manage, annotate, and distribute tissue, blood and urine specimens from consented patients. The UACC biorepository consists of a central collection that includes surgical specimens from multiple organ sites and several special collections developed as the result of several large grants. An oversight committee prioritizes specimen use. The TACMASR provides the following services: 1) biorepository services for high quality sample collection, storage, preparation, and processing as well as consultation, 2) histology and immunohistochemistry, 3) cellular and molecular pathology, 4) microscopy (brightfield, phase contrast, and widefield fluorescence), and 5) education about associated techniques and data analysis. The TACMASR also provides consultation and assistance concerning experimental design, sample preparation, probe selection, and referrals to resources for data analysis. The TACMASR has contributed to major national biorepository efforts, including the International Genome Consortium, by contributing specimens that were entered into the Cancer Genome Atlas and the Expression Project for Oncology.