Drug Discovery and Biomedical Research Training (DDBRT) Program for Underserved Minority Youth

针对服务不足的少数族裔青年的药物发现和生物医学研究培训 (DDBRT) 计划

• 批准号: 10407963
• 负责人: Yen Dang
• 金额: $ 26.67万
• 依托单位: UNIVERSITY OF MARYLAND EASTERN SHORE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-06-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10407963
• 关键词: 3D Print; Admission activity; Age; Animal Behavior; Antibiotics; Area; Attitude; Awareness; Behavior; Biomedical Research; Clinical Research; College Preparation; Community Pharmacy; County; Critical Thinking; Data; Doctor of Pharmacy; Dosage Forms; Drug Delivery Systems; Drug Design; Drug Targeting; Education; Educational Curriculum; Enrollment; Epilepsy; Faculty; Family; Fostering; Goals; Hand; Health; Healthcare; High Pressure Liquid Chromatography; High School Student; Hospitals; Institution; Instruction; Kinesiology; Learning; Link; Low income; Malignant neoplasm of prostate; Maryland; Mentors; Methodology; Methods; Minority Groups; Modeling; Nanotechnology; Outcome; Pharmacologic Substance; Pharmacy Schools; Pharmacy Students; Pharmacy facility; Poverty; Research; Research Methodology; Research Personnel; Research Training; Rotation; Rural; STEM career; Schools; Science; Science, Technology, Engineering and Mathematics Education; Scientist; Series; Specialist; Structure; Students; Support System; Talents; Training; Training Activity; Training Programs; Training and Education; Universities; Virus Diseases; Youth; career; cohort; college; design; disorder prevention; drug discovery; drug synthesis; experience; faculty mentor; follow-up; graduate student; hands on research; high school; high school program; improved; indexing; interest; invention; laboratory experience; low socioeconomic status; malignant breast neoplasm; minority children; minority communities; minority student; opioid abuse; outreach; peer; peer coaching; programs; role model; rural area; science teacher; skills; student training; supportive environment; targeted biomarker; teacher; tool; twelfth grade; underserved area; underserved minority; underserved students

Project Summary/Abstract: The Drug Discovery and Biomedical Research Training (DDBRT) Program is a partnership between the University of Maryland Eastern Shore (UMES) School of Pharmacy and High Schools in Somerset County ,MD, one of the most rural and underserved areas in the State of Maryland. Minority youth residing in rural areas and coming from families from a low socioeconomic status have practically no chance of experiencing the research methodology and tools used in drug discovery and biomedical research. Studies continue to show that students who demonstrate a strong talent and interest in STEM are most influenced by extracurricular and hands-on laboratory experiences. The primary goal of this program is to train and provide mentoring to minority youth in research methods of drug discovery and biomedical research to motivate their interest to pursue education and careers in the applied healthcare fields and biomedical research. Partnering with science teachers from Somerset County, MD an integrated curriculum was developed that builds on the high school biomedical program (4 courses in 10th-12th grades) and links it to drug discovery and biomedical research hands-on training modules led by an experienced pharmaceutical researchers using state-of-the-art biomedical methodology on the UMES campus. Over the course of the 2-year program, the students will experience hand-on modules designed with teacher input that span the following topics: Drug design and synthesis: hitting the epilepsy target, biomarkers: what are they?, pharmaceutical compounding, opioid abuse, community pharmacy rotation, kinesiology, promoting healthy behaviors & disease prevention, hospital pharmacy rotation, animal behavior, viral infection, prostate cancer, breast cancer, nanotechnology for targeted drug delivery, dosage form design by 3D-printing, analysis by high performance liquid chromatography and antibiotic discovery research. A mentoring program that includes faculty as well as Pharm D/graduate students who are mostly minority students aims to provide a support system to the high school students. In addition to facilitating the training, the pharmacy students will each be assigned a group of 2-4 high school students to follow up during and after the end of the program. The expected outcome is to provide continuing support after the end of the program to all our high school student cohorts with a near-peer role models thereby encouraging them to keep focused on moving forward with the STEM career plans and to provide guidance on college readiness. Overall, the expected outcome of DDBRT is a participatory research program with mentoring support designed to stimulate the student’s interest in and pursuit of pharmaceutical, health-related and biomedical research careers and ultimately enhancing the diversity of the biomedical research workforce.

项目概要/摘要： 药物发现和生物医学研究培训（DDBRT）计划是一个合作伙伴关系， 位于马里兰州萨默塞特县的马里兰州东海岸大学（UMES）药学院和高中， 是马里兰州最偏远、服务最差的地区之一。居住在农村地区的少数民族青年， 来自低社会经济地位的家庭几乎没有机会体验这项研究 用于药物发现和生物医学研究的方法和工具。研究表明，学生 那些在STEM方面表现出强大天赋和兴趣的人最受课外和实践的影响 实验室经验该计划的主要目标是培训和指导少数民族青年， 药物发现和生物医学研究的研究方法，以激发他们追求教育的兴趣， 应用医疗保健领域和生物医学研究的职业。与科学教师合作， 医学博士萨默塞特县在高中生物医学课程的基础上开发了一套综合课程 （10 - 12年级的4门课程），并将其与药物发现和生物医学研究实践培训模块联系起来 由经验丰富的制药研究人员领导，在UMES上使用最先进的生物医学方法 校园在为期2年的课程中，学生将体验设计的动手模块， 教师意见涵盖以下主题：药物设计和合成：击中癫痫目标，生物标志物： 它们是什么？药物合成，阿片类药物滥用，社区药房轮换，运动机能学， 促进健康行为和疾病预防，医院药房轮换，动物行为，病毒感染， 前列腺癌、乳腺癌、用于靶向药物递送的纳米技术、通过3D打印的剂型设计、 通过高效液相色谱分析和抗生素发现研究。辅导计划 包括教师以及Pharm D/研究生，他们大多是少数民族学生，旨在提供一个 对高中生的支持系统。除了促进培训，药学专业的学生将 每名学生被分配一组2-4名高中生，在项目期间和项目结束后进行跟踪。的 预期的结果是在项目结束后为所有高中生提供持续的支持 同龄人的榜样，从而鼓励他们继续专注于向前迈进， STEM职业计划，并提供大学准备指导。 总的来说，DDBRT的预期成果是一个参与性研究计划， 激发学生对制药，健康相关和生物医学研究的兴趣和追求 职业生涯，并最终提高生物医学研究队伍的多样性。