Deprescribing for Older Dialysis Patients

取消老年透析患者的处方

基本信息

  • 批准号:
    10408111
  • 负责人:
  • 金额:
    $ 22.28万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2018
  • 资助国家:
    美国
  • 起止时间:
    2018-08-01 至 2024-05-31
  • 项目状态:
    已结题

项目摘要

ABSTRACT This is a Beeson Emerging Leaders in Aging career development award (K76) for Dr. Rasheeda Hall, MD, MBA, MHS. Dr. Hall is a nephrologist who conducts aging research at Duke University, and her long-term goal is to become a leader in geriatric nephrology and develop effective interventions targeting geriatric conditions in older dialysis patients. Compared to older adults without kidney disease, older dialysis patients are more likely develop severe cognitive impairment, experience more falls, and have more frequent hospitalizations. These adverse outcomes are also known to be associated with potentially inappropriate medications, and older dialysis patients are highly susceptible to adverse effects of potentially inappropriate medications because of altered medication clearance due to absent kidney function and common occurrences of hypotension and mini- strokes. Given this susceptibility, reduction of potentially inappropriate medications is a logical goal for improving quality of care for these vulnerable patients. The objective of Dr. Hall’s proposed research is to develop an evidence-based strategy to reduce inappropriate prescribing in older dialysis patients. The research aims are to: 1) identify the prevalence of specific potentially inappropriate medications and the extent to which there is an association with hospitalization risk in prevalent older dialysis patients, 2) identify elements of a deprescribing intervention that are acceptable to nephrologists, primary care providers, and patients, and 3) determine the feasibility of a deprescribing intervention tailored for older dialysis patients. This work will provide evidence to support a definitive clinical trial of deprescribing in dialysis units. Effective deprescribing interventions have the potential to reduce hospitalizations and ameliorate geriatric syndromes in dialysis patients which is consistent with NIA’s mission. Complementary to this research, this career development award will solidify Dr. Hall’s transition to research independence through coursework and mentoring to: a) fill knowledge gaps in directing a team of statisticians, interpretation of pharmacoepidemiologic data, advanced methods in handling bias in observational data, timely qualitative analyses, execution of a pilot study, and clinical trial design; b) enhance her leadership skills; and c) successfully compete for a R01. Duke University is the ideal environment for Dr. Hall to pursue this research career development because of the strong aging research expertise housed in its Center for Aging and affiliated Pepper Center, as well as, rich resources available through Duke’s Clinical and Translational Institute.
摘要

项目成果

期刊论文数量(8)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Drawing Attention to Potentially Inappropriate Medications for Older Adults Receiving Dialysis.
提请注意对于接受透析的老年人可能不合适的药物。
Psychosocial determinants of cardiovascular events among black Americans with chronic kidney disease or associated risk factors in the Jackson heart study.
  • DOI:
    10.1186/s12882-021-02594-6
  • 发表时间:
    2021-11-11
  • 期刊:
  • 影响因子:
    2.3
  • 作者:
    Bhavsar NA;Davenport CA;Yang LZ;Peskoe S;Scialla JJ;Hall RK;Tyson CC;Strigo T;Sims M;Pendergast J;Curtis LH;Boulware LE;Diamantidis CJ
  • 通讯作者:
    Diamantidis CJ
Medication Reconciliation: The Foundation of Medication Safety for Patients Requiring Dialysis.
Clin-Star corner: What is new at the interface of geriatrics and nephrology?
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Rasheeda K Hall其他文献

Rasheeda K Hall的其他文献

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{{ truncateString('Rasheeda K Hall', 18)}}的其他基金

Integration of Geriatric Care into Dialysis Clinics
将老年护理纳入透析诊所
  • 批准号:
    10655156
  • 财政年份:
    2023
  • 资助金额:
    $ 22.28万
  • 项目类别:
Deprescribing for Older Dialysis Patients
取消老年透析患者的处方
  • 批准号:
    9925719
  • 财政年份:
    2018
  • 资助金额:
    $ 22.28万
  • 项目类别:
Deprescribing for Older Dialysis Patients
取消老年透析患者的处方
  • 批准号:
    10161708
  • 财政年份:
    2018
  • 资助金额:
    $ 22.28万
  • 项目类别:
Improving Quality of Life Measurement in Older Dialysis Patients
改善老年透析患者的生活质量测量
  • 批准号:
    8956917
  • 财政年份:
    2015
  • 资助金额:
    $ 22.28万
  • 项目类别:
Improving Quality of Life Measurement in Older Dialysis Patients
改善老年透析患者的生活质量测量
  • 批准号:
    9123490
  • 财政年份:
    2015
  • 资助金额:
    $ 22.28万
  • 项目类别:
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