Molecular, Cellular, and Developmental Mechanisms

分子、细胞和发育机制

• 批准号: 10409972
• 负责人: David L. Van Vactor
• 金额: $ 104.07万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10409972
• 关键词: Development; Molecular

Project Summary/Abstract In the 21st century, advances in knowledge, research technologies, and analytical tools have created unprecedented opportunities for major breakthroughs in our understanding of fundamental biological principles and their underlying mechanisms. We propose here a new interdisciplinary program in Molecular, Cellular, and Developmental Mechanisms (MCDM) at Harvard Medical School (HMS) that will build on our recent investments in science infrastructure, education, and training. Our goal is to educate a diverse, rigorous, and independent group of scientists who will identify novel essential questions in mechanistic biology and develop incisive tools for addressing them. Based on our successful predecessor T32 program, we plan to recruit a group of 20 trainees per year beginning in their second year of graduate study from the Biological and Biomedical Sciences umbrella program. These 20 trainees will distribute across a group of 80 MCDM preceptor laboratories. Our approach to cultivating a resilient and creative group of scholars will be both evidence-based and student-centered. We will bring innovative programming to an exceptionally talented pool of trainees. Through continuous improvements in mentorship practice, community engagement and inclusion, we will foster a collaborative community of scholars who are well-prepared to make confident and transformative contributions to life science research and the many research-related careers needed to convert new discoveries about fundamental biological mechanisms into biomedical and life-sciences applications.

项目总结/摘要 在21世纪，知识、研究技术和分析工具的进步创造了 在我们对基本生物学原理的理解上取得重大突破的前所未有的机会 及其潜在机制。我们在这里提出了一个新的跨学科计划，在分子，细胞， 发展机制（MCDM）在哈佛医学院（HMS），将建立在我们最近的投资 在科学基础设施、教育和培训方面。我们的目标是培养一个多元化，严谨，独立的 一组科学家，他们将确定机械生物学中的新的基本问题，并开发出精辟的工具 来解决这些问题。基于我们成功的前身T32计划，我们计划招募一批20名学员 从生物和生物医学科学研究生学习的第二年开始， 程序.这20名受训人员将分布在80个MCDM指导实验室中。我们的方法来 培养一批有活力和创造力的学者将既以证据为基础，又以学生为中心。我们将 将创新的节目制作带给一群才华横溢的学员。通过不断改进 在师友实践、社区参与和共融方面，我们将培养一个协作的社区， 学者谁是做好准备，使自信和变革性的贡献，生命科学研究和 许多与研究相关的职业需要转化有关基本生物机制的新发现， 生物医学和生命科学的应用。