Comparing a recommendation for self-paced versus moderate intensity physical activity for midlife adults: an RCT

比较中年成年人自定进度体育活动与中等强度体育活动的建议：随机对照试验

• 批准号: 10410549
• 负责人: David M Williams
• 金额: $ 46.48万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-15 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10410549
• 关键词: Accelerometer; Adherence; Adult; Affective; Age; Alzheimer' s Disease; Behavior; Body Weight Changes; Body Weight decreased; Cardiovascular Diseases; Cessation of life; Chronic Disease; Colon Carcinoma; Data; Dementia; Energy Metabolism; Exercise; Exertion; Feeling; Frequencies; Guidelines; Health Benefit; Heart Rate; Laboratory Study; Lead; Malignant Neoplasms; Maximum Heart Rate; Measurement; Measures; Mediation; Mediator of activation protein; Methods; Modeling; Morbidity - disease rate; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Osteoporosis; Overweight; Participant; Patient Self-Report; Persons; Physical activity; Physical assessment; Pilot Projects; Play; Population; Procedures; Protocols documentation; Public Health; Randomized; Recommendation; Research; Risk; Role; Secondary to; Self Determination; Testing; Walking; Weight; Weight Gain; Weight maintenance regimen; World Health Organization; adult obesity; age related; base; displeasure; exercise adherence; exercise prescription; experience; fitness; follow-up; heart disease risk; hedonic; improved; malignant breast neoplasm; middle age; novel strategies; overweight adults; pleasure; premature; prevent; primary outcome; programs; protective effect; recruit; response; sarcopenia; secondary analysis; secondary outcome; theories; therapy design; treatment effect; trend; vigorous intensity; weight maintenance

The current USDHHS guidelines recommend that adults expend at least 1000 kcal per week in PA,12 which can be obtained through 150 minutes per week of moderate intensity PA, 75 minutes of vigorous intensity PA, or some combination. However, current estimates suggest that only 3.5% to 43.5% of US adults, and 28% of overweight or obese adults adhere to these recommendations.13-16 Moreover, people across all World Health Organization regions become less active as they age.17 A more progressive decline in PA is seen after age 45- 50.15,18 In essence, PA rates tend to decrease as people age and gain weight while the health benefits of PA become more pronounced. A growing body of research19-36 suggests that a shift in national guidelines to emphasize PA of a self-selected intensity (i.e., self-paced) instead of prescribed moderate intensity PA may result in better adherence to PA programs, particularly among overweight and obese midlife adults.37,38 In the proposed RCT we will conduct a field-based experimental test of the hypothesis that, among overweight and obese midlife (ages 50-64) adults, adherence to PA programs will be improved when PA is explicitly recommended to be self-paced rather than prescribed at moderate intensity. This approach represents an important shift in mindset for those beginning a new program of PA: That is, PA need not be of a certain intensity in order to “count”. If a self-paced recommendation is found to lead to better PA adherence among overweight and obese midlife adults, this could have implications for PA recommendations for that population. Aim 1: We will conduct an RCT comparing the effects of self-paced versus prescribed moderate intensity PA on PA behavior among low-active overweight and obese midlife (ages 50-64) adults (N=240). Based on procedures developed in our pilot, all participants will receive a 12-month intervention designed to help them overcome barriers to regular PA.53 The independent variable will be random assignment to either self-paced or prescribed moderate intensity PA. The primary outcome will be total volume of PA (frequency x duration x intensity) as measured by accelerometry at months 3, 6, 9, and 12. H1: A recommendation for self-paced PA will result in more PA (primary outcome) relative to prescribing moderate intensity PA based on current public health guidelines.12,54-56 Secondary outcomes include: (a) self-reported min/week of PA over the 12-month program, (b) fitness changes, and (c) weight changes at months 6 and 12. Aim 2: Using EMA, we will examine putative mediators of treatment effects based on our conceptual model (see Figure 1). H2: Self-paced PA will lead to a more positive affective response (primary mediator) and thus greater increases in PA behavior.37 Secondary mediators (analogous to secondary outcomes) will include: (a) perceived autonomy, and (b) perceived exertion (RPE).37 Other predictors of PA behavior will also be explored.

目前美国国土安全部的指导方针建议成年人每周至少摄入1000千卡的PA