Enhancing Exercise Intensity, Motivation and Enjoyment for Persons with PD: Comparing Visual Feedback and Competition in A Virtual Cycling Environment (VCYCLE)

提高帕金森病患者的运动强度、动力和乐趣：在虚拟自行车环境 (VCYCLE) 中比较视觉反馈和竞争

• 批准号: 10418641
• 负责人: John Palmieri
• 金额: $ 4.11万
• 依托单位: RBHS-SCHOOL/ HEALTH RELATED PROFESSIONS
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-07 至 2023-04-06
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10418641
• 关键词: Address; Adherence; Adult; Affect; Animal Model; Applied Research; Area; Attention; Autonomic Dysfunction; Behavior; Bicycling; Bradykinesia; Cardiovascular system; Clinical; Clinical assessments; Cognitive deficits; Coupled; Data; Disease; Dopamine; Dopamine Receptor; Educational process of instructing; Elderly; Elements; Emotional; Engineering; Environment; Equilibrium; Equipment; Equipment and supply inventories; Exercise; Exertion; Fatigue; Feedback; Gait; Gait abnormality; Goals; Health; Heart Rate; Human Resources; Knowledge; Laboratories; Measures; Mental Depression; Mentors; Mentorship; Modeling; Motivation; Motor; Movement Disorder Society Unified Parkinson' s Disease Rating Scale; Nerve Degeneration; Neuraxis; Neurologic; Neuronal Plasticity; Parkinson Disease; Participant; Patients; Perception; Personal Satisfaction; Persons; Pharmacotherapy; Population; Posture; Program Accessibility; Quality of life; Rehabilitation therapy; Reporting; Research; Risk; Role; Scientist; Services; Severity of illness; Sleep disturbances; Speed; Stimulus; Strenuous Exercise; System; Therapeutic Effect; Time; Training; Virtual and Augmented reality; Visual attention; Work; base; comorbidity; design; efficacy testing; exercise intensity; exercise program; exercise regimen; exercise training; experience; fitness; graduate student; head mounted display; improved; improved mobility; insight; interest; intrinsic motivation; mentoring community; motor control; motor rehabilitation; neuromuscular; neuromusculoskeletal; non-motor symptom; parent grant; patient population; post stroke; posture instability; programs; side effect; skills; student training; tool; virtual; virtual environment; virtual reality; visual feedback

Project Summary In this single group study of 33 persons with Parkinson's Disease (PD, Hoehn and Yahr Stages II-III) will exercise in two virtual reality augmented bicycling conditions: visual feedback and competition. The primary purpose of the study is to determine which condition of bicycling (visual feedback or competitive) promotes a higher exercise intensity in the neuromusculoskeletal domain (measured by revolutions per minutes on the bicycle) and in the cardiovascular domain (measure by % of max. heart rate) as well as which promotes higher motivation and enjoyment (measured with the Intrinsic Motivation Inventory) and reduced perception of effort (measured with the Borg Scale). The secondary aims are to explore how personal factors (competitiveness) influence the exercise intensity, and whether visual attention can differentiate between the cycling conditions. Data will be collected in a single session consisting of clinical assessments and bicycling for ten minutes for each condition while wearing a head mounted display to interact with the virtual environment. Results from this study will inform the design of optimal exercise programs to make exercise accessible, enjoyable for persons with PD. Those programs will be tested for efficacy at improving mobility and fitness leading to well-being for persons with PD. The proposed project will be undertaken in a well-equipped laboratory under the mentorship of a sponsor with a long track record of designing virtual reality tools for persons with neurologic health conditions. The sponsor has successfully mentored dozens of graduate students including dual-degree students, training to be clinician scientists. Collaborators and contributors from diverse training backgrounds and areas of expertise will work with the sponsor and PI on this project. The PI will couple his previous training in engineering with new skills developed in applied science. The PI's training plan includes goals related to research execution and dissemination, clinical experience, teaching/mentoring, and community/professional service all of which can be realistically achieved.

项目总结