Biostatistics, Epidemiology, and Research Design Core

生物统计学、流行病学和研究设计核心

• 批准号: 10417255
• 负责人: Sona Rivas-Tumanyan
• 金额: $ 33.24万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10417255
• 关键词: Address; Award; Awareness; Big Data; Biometry; Cardiometabolic Disease; Center for Translational Science Activities; Clinical; Clinical Investigator; Clinical Research; Collaborations; Communicable Diseases; Communities; Community Health; Data Analyses; Development; Disasters; Discipline; Disease; Educational Curriculum; Emerging Communicable Diseases; Ensure; Epidemiology; Funding; Funding Mechanisms; Genomics; Goals; Grant; Health; Health Benefit; Healthcare; Hispanic; Hispanic Populations; Information Dissemination; Infrastructure; Institution; Journals; Knowledge; Malignant Neoplasms; Methodology; Methods; Paper; Phase; Play; Positioning Attribute; Proteomics; Publications; Publishing; Puerto Rico; Qualitative Research; Research; Research Design; Research Methodology; Research Personnel; Research Project Grants; Resources; Role; Services; Statistical Data Interpretation; Statistical Methods; Training; Training Programs; Translational Research; United States; analytical method; career; data management; design; epidemiology study; hispanic community; improved; innovation; medically underserved; member; new technology; population health; prevent; recruit; research study; skills; sound; tool; training opportunity

Abstract/Summary The Biostatistics, Epidemiology and Research Design (BERD) Core of the Hispanic Alliance for Translational and Clinical Research (Alliance) aims to provide expertise and support in the design, implementation, and statistical analysis of research projects, as well as research methods training opportunities to Alliance investigators, BERD staff, and the community, which will ultimately improve the health of Hispanic communities in Puerto Rico (PR) and the United States. Our long-term goal is to improve the overall quality of clinical and translational research studies conducted by Alliance investigators. Appropriate methods and analysis will promote the advancement of research through further funding, and underpin the development of strategies to prevent and treat diseases and conditions prevalent in Hispanic populations. Properly designed and conducted (i.e., epidemiologically and statistically sound) studies will help ensure dissemination of results in high -impact journals. Through a centralized unit with available expertise, we will address the increasing demand for epidemiology and biostatistics services and contribute to the professional development of statisticians working in Alliance institutions, especially in new and advanced methods. BERD Core has recruited and established collaborations with experts with specialized knowledge from Alliance and other institutions, who would otherwise not be available for Alliance investigators. Development and expansion of alternative funding mechanisms will ensure long-term feasibility of these services. BERD will address the long-term goal with a combination of proven and new mechanisms in the following aims: Specific Aim 1. Provide epidemiological and biostatistical expertise and support for design, implementation, and analysis of clinical and translational research projects focused on health conditions prevalent in Hispanic communities in Puerto Rico and across the United States. Specific Aim 2. Develop and implement training programs to increase knowledge and skills in research design, data management, and statistical methods, for Alliance investigators, BERD staff, and community leaders and members. Specific Aim 3. Establish and strengthen working relationships of BERD with other IDeA institutions and Clinical and Translational Research Centers (CTRCs), and other external consultants. BERD expects that increased knowledge and improved support for researchers in biostatistics and epidemiology will lead to improved quality of research and therefore more grants awarded and papers in high-impact journals. Established, as well as innovative tools and methods, such as advanced user forums and new statistical tools and macros, will strengthen BERD as a hub for epidemiology and biostatistics expertise.

摘要/摘要 拉美裔翻译联盟的生物统计学、流行病学和研究设计(BERD)核心 和临床研究(联盟)的目标是在设计、实施和 研究项目统计分析，以及对联盟的研究方法培训机会 调查人员、BERD工作人员和社区，这最终将改善拉美裔社区的健康 在波多黎各(PR)和美国。我们的长期目标是提高临床和医疗服务的整体质量 由联盟调查人员进行的翻译研究。适当的方法和分析将 通过进一步的资助促进研究的进展，并支持制定战略以 预防和治疗拉美裔人群中流行的疾病和状况。适当地设计和实施 (即流行病学和统计学上合理的)研究将有助于确保在高影响地区传播结果 日记。通过一个拥有现有专业知识的中央单位，我们将满足日益增长的对 流行病学和生物统计服务，并有助于统计人员的职业发展 在联盟机构中，特别是在新的和先进的方法方面。Berd Core已经招募并建立了 与来自联盟和其他机构的具有专业知识的专家合作，他们将 否则，联盟调查人员将无法获得。发展和扩大替代筹资 这些机制将确保这些服务的长期可行性。Berd将通过一项 在以下目标中结合已证实的机制和新机制：具体目标1.提供流行病学和 生物统计学专业知识和对临床和翻译的设计、实施和分析的支持 研究项目侧重于波多黎各和其他地区拉美裔社区普遍存在的健康状况 美国。具体目标2.制定和实施培训方案，以增加知识和技能 在研究设计、数据管理和统计方法方面，为联盟调查人员、BERD工作人员和 社区领袖和成员。具体目标3.建立和加强BERD与 其他创意机构、临床和转化研究中心(CTRC)以及其他外部机构 顾问。Berd希望增加对生物统计学研究人员的知识和支持 和流行病学将导致研究质量的提高，从而获得更多的拨款和论文 影响力很大的期刊。建立以及创新的工具和方法，如高级用户论坛 以及新的统计工具和宏，将加强BERD作为流行病学和生物统计中心的地位 专业知识。